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Inhibition of Class I Histone Deacetylase Enhances Self-Reprogramming of Spermatogonial Stem Cells into Pluripotent Stem Cells

Lee Y, Lee SW, Jeong D, Lee HJ, Choi NY, Bang JS, Ham S, Ko K

Background and Objectives: Spermatogonial stem cells (SSCs) are the most primitive cells in spermatogenesis and are the only adult stem cells capable of passing on the genome of a given...
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COVID-19 Sequelae and Their Implications on Social Services

Kim SG, Kwon HC, Kang TK, Kwak MY, Lee S, Lee K, Ko K

Background: The impact of persistent coronavirus disease 2019 (COVID-19) symptoms on quality of life remains unclear. This study aimed to describe such persistent symptoms and their relationships with quality of...
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Urinary beta-2-microglobulin is associated with allograft function and rapid renal function decline in kidney transplant recipients

Jeon HJ, Shin DH, Oh J, Kee YK, Park JY, Ko K, Lee S

Background: Urinary beta-2-microglobulin (B2MG) has been known as a biomarker for chronic kidney disease. The aim of this study was to investigate the association of urinary B2MG with allograft function...
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DNA test to distinguish de novo transitional cell carcinoma from donor-derived malignancy: a case report

Ko K, Kim D, Jeon HJ, Jeong HC, Ko K

Background: Transitional cell carcinoma (TCC) of urinary tract appears more common in kidney transplantation recipients than in general population. De novo TCC after renal transplantation was treated with transurethral resection...
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Immune Responses to Plant-Derived Recombinant Colorectal Cancer Glycoprotein EpCAM-FcK Fusion Protein in Mice

Lim CY, Kim DS, Kang Y, Lee YR, Kim K, Kim DS, Kim MS, Ko K

Epidermal cell adhesion molecule (EpCAM) is a tumor-associated antigen (TAA), which has been considered as a cancer vaccine candidate. The EpCAM protein fused to the fragment crystallizable region of immunoglobulin...
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Inequalities in External-Cause Mortality in 2018 across Industries in Republic of Korea

Lim J, Ko K, Lee KE, Park JB, Lee S, Jeong I

Background External-cause mortality is an important public health issue worldwide. Considering its significance to workers’ health and inequalities across industries, we aimed to describe the state of external-cause mortality and investigate...
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Validation of the Korean Version of the Anosognosia Questionnaire for Dementia

Byeon GH, Kim WJ, Byun MS, Lee JH, Jeon SY, Ko K, Sung K, Han D, Joung H, Lee Y, Jung G, Lee HN, Yi D, Lee DY, KBASE Research Group

Objective Anosognosia is a common phenomenon in individuals with dementia. Anosognosia Questionnaire for dementia (AQ-D) is a well-known scale for evaluating anosognosia. This study aimed to establish a Korean version...
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Peanut Sprout Extracts Cultivated with Fermented Sawdust Medium Inhibits Benign Prostatic Hyperplasia In Vitro and In Vivo

Song JH, Hwang B, Chung HJ, Moon B, Kim JW, Ko K, Kim BW, Kim WR, Kim WJ, Myung SC, Moon SK

Purpose: In this study, we tested whether the resveratrol-enriched peanut sprout extracts cultivated with fermented sawdust medium (PSEFS) could suppress benign prostatic hyperplasia (BPH) in vitro and in vivo. Materials and...
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Reprogramming of Cancer Cells into Induced Pluripotent Stem Cells Questioned

Bang JS, Choi NY, Lee M, Ko K, Park YS, Ko K

BACKGROUND AND OBJECTIVES: Several recent studies have claimed that cancer cells can be reprogrammed into induced pluripotent stem cells (iPSCs). However, in most cases, cancer cells seem to be resistant...
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Prevalence of Women with Dense Breasts in Korea: Results from a Nationwide Cross-sectional Study

Jo HM, Lee EH, Ko K, Kang BJ, Cha JH, Yi A, Jung HK, Jun JK, On behalf of the Alliance for Breast Cancer Screening in Korea (ABCS-K)

PURPOSE: Women with dense breast are known to be at high risk for breast cancer, but their prevalence and number of Korean women are unknown. The current study was to...
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Alteration of Genomic Imprinting Status of Human Parthenogenetic Induced Pluripotent Stem Cells during Neural Lineage Differentiation

Lee HJ, Choi NY, Lee SW, Lee Y, Ko K, Kim GJ, Hwang HS, Ko K

BACKGROUND AND OBJECTIVES: Genomic imprinting modulates growth and development in mammals and is associated with genetic disorders. Although uniparental embryonic stem cells have been used to study genomic imprinting, there...
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Clinical Characteristics of Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Patients with R544C Mutation Aged 90 or Older

Ko K, Lee J

Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy is an inherited small vessel diseases caused by mutations in the Notch3 gene. In Caucasian patients, the average life expectancy was 65...
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Postmicturition Dribble Is Associated with Erectile Dysfunction in Middle-Aged and Older Men with Lower Urinary Tract Symptoms

Yang DY, Ko K, Lee SH, Cho JS, Lee SK, Shin TY, Lee WK

PURPOSE: Lower urinary tract symptoms (LUTS) are correlated with erectile dysfunction (ED), but research on whether postmicturition dribble (PMD) is related to ED is limited. We assessed the correlation between...
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Simultaneous Determination of Four Compounds from Artemisia capillaris using High Performance Liquid Chromatography-Ultraviolet Detector (HPLC-UVD) and Their Quantitative Study in Artemisia Genus

Ko K, Hong IK, Cho HJ, Kim YH, Yang H

Artemisia capillaris Thunb. (Compositae) is a native herb of East Asian countries and has used for the treatment of jaundice, high liver fever, and digestive diseases for a long time,...
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Let Archived Paraffin Blocks Be Utilized for Research with Waiver of Informed Consent

Kim YJ, Park JS, Ko K, Jeong CR

Advances in biomedical and genetic research have contributed to more effective public health improvement via bench-to-bed research and the emergence of personalized medicine. This has certainly showcased the importance of...
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Subarachnoid Hemorrhage with Subdural Hematoma due to Ruptured De Novo Aneurysm after Aneurysmal Clipping via Pterional Approach: An Autopsy Case

Choi J, Kim JY, Jang H, Ko K, Park SH

Subdural hematoma (SDH) due to spontaneous rupture of intracranial aneurysm rarely occurs. The prevalence of subarachnoid hemorrhage (SAH) with SDH is approximately 0.5%–10.3% of all aneurysmal SAH. We report a...
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Erratum: Follow-up Outcomes of Benign Pathology Initially Assigned as Breast Imaging Reporting and Data System Category 4A and 3

You JY, Suh HJ, Kim Y, Jun JK, Ojeda-Fournier H, Ko K

This article was initially published on the Journal of Breast Cancer with a misspelled the Institutional Review Board (IRB) approval number. The IRB number should be corrected as “NCC2014-0031”.
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Follow-up Outcomes of Benign Pathology Initially Assigned as Breast Imaging Reporting and Data System Category 4A and 3

You JY, Suh HJ, Kim Y, Jun JK, Ojeda-Fournier H, Ko K

PURPOSE: This retrospective study investigated if the initially assigned category 4A or 3 in concordant benign lesions, after ultrasound (US)-guided core needle biopsy, could affect follow-up compliance. METHODS: Eight hundred thirty-eight...
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Effect of Fenofibrate Medication on Renal Function

Kim S, Ko K, Park S, Lee DR, Lee J

BACKGROUND: Fibrates are widely used to treat hypertriglyceridemia, a risk factor for arteriosclerosis, but these compounds have been associated with renal dysfunction. This study aimed to investigate the effects of...
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Production of Recombinant Anti-Cancer Vaccines in Plants

Lee JH, Ko K

Plant expression systems have been developed to produce anti-cancer vaccines. Plants have several advantages as bioreactors for the production of subunit vaccines: they are considered safe, and may be used...
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