Korean J Radiol.  2009 Aug;10(4):407-410. 10.3348/kjr.2009.10.4.407.

Primary Primitive Neuroectodermal Tumor of the Breast: a Case Report

• Ko K
• Kim EA
• Lee ES
• Kwon Y

• KMID: 1777271
• DOI: http://doi.org/10.3348/kjr.2009.10.4.407

Abstract

Primary primitive neuroectodermal tumors (PNET) are rare malignant tumors, affecting mostly children and adolescents. Only three cases of primary breast PNETs have been reported in the medical literature, with none in Korea. We present a case of a primary PNET of the breast in a 33-year-old woman, with imaging and immunohistopathology findings.

Keyword

Primitive neuroectodermal tumor (PNET); Breast; Sarcoma

MeSH Terms

Adult
Breast Neoplasms/*diagnosis/pathology
Female
Humans
Immunohistochemistry
Mammography
Neuroectodermal Tumors/*diagnosis/pathology
Positron-Emission Tomography

Figure

• 

  Fig. 1 Primary primitive neuroectodermal tumors in 33-year-old woman with palpable mass in left breast. A. Mediolateral oblique mammogram of left breast shows ill-defined, isodense mass deep in upper inner quadrant (arrows). B. Sonography reveals two adjacent, circumscribed, oval, homogeneously hypoechoic masses with posterior acoustic enhancement. C. On breast MRI, mass showed intermediate signal intensity on T1-weighted image (T1) and high signal intensity on T2-weighted image (T2). Intense enhancement was seen during contrast enhancement (CE) (arrows). D. Grossly, tumor is well-circumscribed, grayish tan, fish flesh, and slightly friable (black arrows). E. Microscopically, tumor is composed of small, round cells with inconspicuous nucleoli and scanty cytoplasm, which are arranged in sheets or solid nests (Hematoxylin & Eosin staining, ×200). F. On immunohistochemical staining, tumor cells show strong membranous immunoreactivity for CD99.

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