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Kinesin Spindle Protein Inhibition in Translational Research

Nyamaa B, Kim HK, Jeong YJ, Song IS, Han J

The kinesin superfamily is a class of motor proteins moving along microtubule filaments and playing essential roles in mitosis of eukaryotic cells. In the cancer biology, mitotic activity is an...
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Molecular Motor Proteins of the Kinesin Superfamily Proteins (KIFs): Structure, Cargo and Disease

Seog DH, Lee DH, Lee SK

Intracellular organelle transport is essential for morphogenesis and functioning of the cell. Kinesins and kinesin-related proteins make up a large superfamily of molecular motors that transport cargoes such as vesicles,...
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Kinesin superfamily protein member 4 (KIF4) is localized to midzone and midbody in dividing cells

Lee YM, Kim W

  • KMID: 755671
  • Exp Mol Med.
  • 2004 Feb;36(1):93-97.
In association with microtubules, a variety of kinesins play important roles in cellular functions such as intracellular transport of organelles or vesicles, signal transduction, and cell division. In a previous...
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Sorting Nexin 17 Interacts Directly with Kinesin Superfamily KIF1B beta Protein

Seog DH, Han J

KIF1B beta is a member of the Kinesin superfamily proteins (KIFs), which are microtubule-dependent molecular motors that are involved in various intracellular organellar transport processes. KIF1B beta is not restricted...
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Kinesin Superfamily KIF1Balpha Protein Binds to the PDZ Domain of MALS-3

Kim SJ, Lee CH, Park HY, Yea SS, Jang WH, Lee SK, Park YH, Jung Y, Seog DH

  • KMID: 2092879
  • Korean J Anat.
  • 2006 Oct;39(5):375-382.
The Kinesin superfamily proteins (KIFs) make up a large superfamily of molecular motors that transport cargo such as vesicles, protein complexes, and organelles. KIF1Balpha is a monomeric motor that conveys mitochondria and...
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Kinesin Superfamily KIF5 Proteins Bind to betaIII Spectrin

Paik JE, Kim N, Yea SS, Jang WH, Chung JY, Lee SK, Park YH, Han J, Seog DH

  • KMID: 2285302
  • Korean J Physiol Pharmacol.
  • 2004 Jun;8(3):167-172.
The kinesin proteins (KIFs) make up a large superfamily of molecular motors that transport cargo such as vesicles, protein complexes, and organelles. KIF5 is a heterotetrameric motor that conveys vesicles...
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Kinesin Superfamily KIF1A Protein Binds to Synaptotagmin XI

Park HY, Yea SS, Jang WH, Chung JY, Lee SK, Kim SJ, Yang YI, Kim JY, Park YH, Seog DH

  • KMID: 2092858
  • Korean J Anat.
  • 2005 Oct;38(5):403-411.
The kinesin proteins (KIFs) make up a large superfamily of molecular motors that transport cargo such as vesicles, protein complexes, and organelles. KIF1A is a monomeric motor that conveys synaptic vesicle...
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The Motile Properties of Vimentin Intermediate Filament in B16 Melanoma Cells

Yoon KH, Ha SW, Kang HY, Lee ES, Kang WH

  • KMID: 1619872
  • Korean J Dermatol.
  • 2003 Mar;41(3):293-301.
BACKGROUND: Intermediate filaments as well as microtubule and microfilament are major components of cytoskeleton of human cells. Melanocytes have vimentin intermediate filament, which have not been well investigated as other...
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Meta-analysis of the correlation between the rs17401966 polymorphism in kinesin family member 1B and susceptibility to hepatitis B virus related hepatocellular carcinoma

Su M, Guo J, Huang J

BACKGROUND/AIMS: The association between the kinesin family member 1B (KIF1B) gene polymorphism and the risk of hepatitis B virus-related hepatocellular carcinoma (HCC) has been investigated in many peer-reviewed studies. However,...
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Kinesin Family Member 11 Enhances the Self-Renewal Ability of Breast Cancer Cells by Participating in the Wnt/β-Catenin Pathway

Pei YY, Li GC, Ran J, Wan XH, Wei FX, Wang L

PURPOSE: Our previous studies have shown that kinesin family member 11 (KIF11) is markedly overexpressed in human breast cancer cells or tissues and positively correlated with distant metastasis and prognosis...
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RNA Granules and Stress Granules in Virus Systems

Kim K

Viruses initiate a number of cellular stress responses and modulate gene regulation and compartmentalization of RNA upon infection to be successful parasites. Virus infections may induce or impair stress granule...
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Differential gene expression pattern in brains of acrylamide-administered mice

Han CH

  • KMID: 1435820
  • Korean J Vet Res.
  • 2012 Jun;52(2):99-104.
The present study was performed to evaluate the relationship between the neurotoxicity of acrylamide and the differential gene expression pattern in mice. Both locomotor test and rota-rod test showed that...
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RET Fusion Genes in Korean Non-Small Cell Lung Cancer

Yoo SS, Jin G, Jung HJ, Hong MJ, Choi JE, Jeon HS, Lee SY, Lim JO, Park JY

Recently, rearranged during transfection (RET) fusions have been identified in approximately 1% of non-small cell lung cancer (NSCLC). To know the prevalence of RET fusion genes in Korean NSCLCs, we...
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Silencing of KIF14 interferes with cell cycle progression and cytokinesis by blocking the p27(Kip1) ubiquitination pathway in hepatocellular carcinoma

Xu H, Choe C, Shin SH, Park SW, Kim HS, Jung SH, Yim SH, Kim TM, Chung YJ

Although it has been suggested that kinesin family member 14 (KIF14) has oncogenic potential in various cancers, including hepatocellular carcinoma (HCC), the molecular mechanism of this potential remains unknown. We...
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AKAP12 regulates vascular integrity in zebrafish

Kwon HB, Choi YK, Lim JJ, Kwon SH, Her S, Kim HJ, Lim KJ, Ahn JC, Kim YM, Bae MK, Park JA, Jeong CH, Mochizuki , Kim KW

The integrity of blood vessels controls vascular permeability and extravasation of blood cells, across the endothelium. Thus, the impairment of endothelial integrity leads to hemorrhage, edema, and inflammatory infiltration. However,...
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