- Effects of N-Acetylcysteine on Nicotinamide Dinucleotide Phosphate Oxidase Activation and Antioxidant Status in Heart, Lung, Liver and Kidney in Streptozotocin-Induced Diabetic Rats
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Lei S, Liu Y, Liu H, Yu H, Wang H, Xia Z
- KMID: 1120195
- Yonsei Med J.
- 2012 Mar;53(2):294-303.
- doi: 10.3349/ymj.2012.53.2.294
PURPOSE: Hyperglycemia increases reactive oxygen species (ROS) and the resulting oxidative stress plays a key role in the pathogenesis of diabetic complications. Nicotinamide dinucleotide phosphate (NADPH) oxidase is one of... -
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- Protective Effects of Curcumin on Renal Oxidative Stress and Lipid Metabolism in a Rat Model of Type 2 Diabetic Nephropathy
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Kim BH, Lee ES, Choi R, Nawaboot J, Lee MY, Lee EY, Kim HS, Chung CH
- KMID: 2374087
- Yonsei Med J.
- 2016 May;57(3):664-673.
- doi: 10.3349/ymj.2016.57.3.664
PURPOSE: Diabetic nephropathy is a serious complication of type 2 diabetes mellitus, and delaying the development of diabetic nephropathy in patients with diabetes mellitus is very important. In this study,... -
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- Repeated dose toxicity of alfa-cypermethrin in rats
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Manna S, Bhattacharyya D, Mandal TK, Das S
- KMID: 1099838
- J Vet Sci.
- 2004 Sep;5(3):241-245.
The present study was performed to investigate the subacute effect of alpha-cypermethrin (alpha-CP) in rats. Alfacypermethrin a synthetic pyrethroid insecticide, dissolved in dimethyl sulfoxide (DMSO) and oral LD50 was investigated... -
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- Increased Expression of Sodium Transporters in Rats Chronically Inhibited of Nitric Oxide Synthesis
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Kim JS, Choi KC, Jeong MH, Kim SW, Oh YW, Lee JU
- KMID: 2157772
- J Korean Med Sci.
- 2006 Feb;21(1):1-4.
- doi: 10.3346/jkms.2006.21.1.1
The present study was done to determine whether endogenous nitric oxide (NO) plays a role in the regulation of sodium transporters in the kidney. Male Sprague-Dawley rats were treated with... -
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- Hepatic Ischemic Preconditioning Provides Protection Against Distant Renal Ischemia and Reperfusion Injury in Mice
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Lee JA, Choi JW, In JH, Jung HS, Kim YS, Jeon YS, Kang YJ, Kim DW, Lim YG, Park JH, Joo JD
- KMID: 1372799
- J Korean Med Sci.
- 2012 May;27(5):547-552.
- doi: 10.3346/jkms.2012.27.5.547
We previously demonstrated that there are acute and delayed phases of renal protection against renal ischemia and reperfusion (IR) injury with renal ischemic preconditioning (IPC). This study assessed whether hepatic... -
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- Pirfenidone Suppressed the Development of Glomerulosclerosis in the FGS/Kist mouse
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Park HS, Bao L, Kim YJ, Cho IH, Lee CH, Hyun BH, Margolin S, Park YH
- KMID: 648904
- J Korean Med Sci.
- 2003 Aug;18(4):527-533.
- doi: 10.3346/jkms.2003.18.4.527
Pirfenidone(PFD) is a newly developed anti-fibrotic agent. We evaluated the effect of PFD for the prevention of renal fibrosis using a spontaneous progressive glomerulosclerosis animal model, FGS/Kist mice. Male and... -
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