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The Medical Science Research and Development Supported by the Korea Science and Engineering Foundation

Min TS, Han J, Kim SY, Rhee BD, Kim MS

This study examined ways of promoting research in the medical sciences by evaluating trends in research funding, and the present status of research funding by the Korea Science and Engineering...
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Giant Cystic Chondroid Hamartoma

Kim GY, Han J, Kim DH, Kim J, Lee KS

We report a case of huge pulmonary chondroid hamartoma with multilocular cysts in a 38-yr-old male patient. The lobectomy specimen of the left lower lobe showed a large multilocular cystic...
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Relationship between Dendritic Cells and Activated Eosinophils in Induced Sputum of Asthmatics

Koh YI, Lee JB, Lee SR, Ji SG, Choi IS

It has been suggested that dendritic cells (DCs) are critical antigen presenting cells for eosinophilic airway inflammation in a mouse model of asthma, and cysteinyl leukotrienes may play a role...
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Normal Gallbladder Visualization during Post-Ablative Iodine-131 Scan of Thyroid Cancer

Seok JW, Kim SJ, Kim IJ, Kim YS, Kim YK

Whole body iodine-131 scan is a well-established imaging method for the detection of metastatic or residual tumor sites in patients with well-differentiated thyroid cancer. Many false-positive iodine-131 scan findings mimicking...
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A Case of Femoral Compressive Neuropathy in AL Amyloidosis

Kang EH, Lee EB, Im CH, Kim JH, Park JJ, Lee JC, Kim SH, Song YW

We describe a case of a 54-yr-old AL amyloidosis patient who developed femoral compressive neuropathy due to iliopsoas pseudohypertrophy. The patient, who presented with end stage renal disease, was referred...
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Genetic and Environmental Influences on Birthweight in a Sample of Korean Twins

Hur YM

This study is the first report of genetic and environmental influences on birthweight using Korean twins. The sample consisted of 255 monozygotic (MZ) and 178 dizygotic (DZ) twin pairs drawn...
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A Case of Reactive Plasmacytosis Mimicking Multiple Myeloma in A Patient with Primary Sjogren's Syndrome

Lee J, Chang JE, Cho YJ, Han WS

Primary Sjogren's syndrome (pSS) is a chronic autoimmune disease with welldocumented association of lymphoid malignancies during the progress of the disease. Although several types of malignancy and pseudomalignancy have been...
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A Case of Hypothyroidism and Type 2 Diabetes Associated with Type V Hyperlipoproteinemia and Eruptive Xanthomas

Park JR, Jung TS, Jung JH, Lee GW, Kim MA, Park KJ, Kim DR, Chang SH, Chung SI, Hahm JR

Primary hypothyroidism and type 2 diabetes are both typically associated with the increased level of triglycerides. To date, there have been only a few case reports of type 2 diabetes...
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Identification of Proteins Differentially Expressed in the Conventional Renal Cell Carcinoma by Proteomic Analysis

Hwa JS, Park HJ, Jung JH, Kam SC, Park HC, Kim CW, Kang KR, Hyun JS, Chung KH

Renal cell carcinoma (RCC) is one of the most malignant tumors in urology, and due to its insidious onset patients frequently have advanced disease at the time of clinical presentation....
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A Novel Mutation (A148V) in the Glucose 6-phosphate Translocase (SLC37A4) Gene in a Korean Patient with Glycogen Storage Disease Type 1b

Han SH, Ki CS, Lee JE, Hong YJ, Son BK, Lee KH, Choe YH, Lee SY, Kim JW

We report a Korean patient with glycogen storage disease type 1b (GSD-1b) whose diagnosis was confirmed by liver biopsy and laboratory results. The patient presented with delay of puberty and...
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A Case of Osteoclast-like Giant Cell Tumor of the Pancreas with Ductal Adenocarcinoma: Histopathological, Immunohistochemical, Ultrastructural and Molecular Biological Studies

Joo YE, Heo T, Park CH, Lee WS, Kim HS, Kim JC, Koh YS, Choi SK, Cho CK, Rew JS, Kim SJ

Osteoclast-like giant cell tumor of the pancreas is a very rare neoplasm, of which the histiogenesis remains controversial. A 63-yr-old woman was hospitalized for evaluation of epigastric pain. An abdominal...
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Selected Adnexal Cystic Masses in Postmenopausal Women Can be Safely Managed by Laparoscopy

Lee JW, Kim CJ, Lee JE, Lee SJ, Kim BG, Lee JH, Bae DS, Park CS

The aim of this study was to assess the efficacy and safety of laparoscopic treatment for adnexal cystic masses that were predicted to be benign in postmenopausal women. Postmenopausal women...
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Clinical Significance of Ki-67 Labeling Index in Pituitary Macroadenoma

Paek KI, Kim SH, Song SH, Choi SW, Koh HS, Youm JY, Kim Y

The aim of our study was to investigate the correlation of the proliferative activity of pituitary neoplasms with clinical characteristics and recurrences. Tumor specimens were obtained from 44 consecutive patients...
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Lung Cancer Screening with Low-Dose Helical CT in Korea: Experiences at the Samsung Medical Center

Chong S, Lee KS, Chung MJ, Kim TS, Kim H, Kwon OJ, Choi YH, Rhee CH

To determine overall detection rates of lung cancer by low-dose CT (LDCT) screening and to compare histopathologic and imaging differences of detected cancers between high- and low-risk groups, this study...
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Concurrent Male Gynecomastia and Testicular Hydrocele after Imatinib Mesylate Treatment of a Gastrointestinal Stromal Tumor

Kim H, Chang HM, Ryu MH, Kim TW, Sohn HJ, Kim SE, Kang HJ, Park S, Lee JS, Kang YK

We report a gastrointestinal stromal tumor (GIST) patient with male gynecomastia and testicular hydrocele after treatment with imatinib mesylate. A 42 yr-old male patient presented for management of hepatic masses....
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Tissue Engineered Vascularized Bone Formation Using in vivo Implanted Osteoblast-Polyglycolic acid Scaffold

Kim WS, Kim HK

Repair of skeletal defects with vascularized bone grafts has many advantages over non-vascularized free grafts, but the availability of these grafts is extremely limited. This study was designed to determine...
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Development of Anthropometry-Based Equations for the Estimation of the Total Body Water in Koreans

Kim MJ, Lee SW, Kim GA, Lim HJ, Lee SY, Park GH, Song JH

For developing race-specific anthropometry-based total body water (TBW) equations, we measured TBW using bioelectrical impedance analysis (TBW(BIA)) in 2,943 healthy Korean adults. Among them, 2,223 were used as a reference...
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Association of Vitamin D Receptor Gene Polymorphism and Parkinson's Disease in Koreans

Kim JS, Kim YI, Song C, Yoon I, Park JW, Choi YB, Kim HT, Lee KS

1alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3), which is the biologically active form of vitamin D, has anti-inflammatory effects and can prevent experimental Parkinson's disease (PD). 1,25(OH)2D3 exerts most of its actions only after...
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An Experimental Animal Model of Fulminant Hepatic Failure in Pigs

Lee KU, Zheng LX, Cho YB, Kim KH, Ha J, Suh KS, Jung SE

The objective of this study was to develop an experimental animal model of fulminant hepatic failure to test the efficacy of the bioartificial liver system. The portal vein and the...
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Hypoadiponectinemia and Insulin Resistance are Associated with Nonalcoholic Fatty Liver Disease

Yoon D, Lee SH, Park HS, Lee JH, Park JS, Cho KH, Kim SM

We investigated the association between nonalcoholic fatty liver disease (NAFLD) and plasma adiponectin levels and insulin resistance. We recruited study subjects among one hundred and eighty one persons who were...
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