J Korean Med Sci.  2005 Jun;20(3):509-511. 10.3346/jkms.2005.20.3.509.

Giant Cystic Chondroid Hamartoma

• Kim GY
• Han J
• Kim DH
• Kim J
• Lee KS

• KMID: 1778517
• DOI: http://doi.org/10.3346/jkms.2005.20.3.509

Abstract

We report a case of huge pulmonary chondroid hamartoma with multilocular cysts in a 38-yr-old male patient. The lobectomy specimen of the left lower lobe showed a large multilocular cystic mass, 11.5 x 10 cm in size. The mass had thin-walled, variable-sized cysts and areas of solid cartilaginous small nodules in the interstitium, which occupied the superior segment and the upper portion of the basal segment. There was no connection with bronchus or vessel. Microscopically, the cysts and cleft-like spaces were lined by ciliated columnar epithelium and the solid components were composed of cartilage, myxohyalinized connective tissue, and adipose tissue. Also seen were foci of calcification within the sclerotic stroma.

Keyword

Hamartoma; Lung Neoplasms; Cysts

MeSH Terms

Adult
Cysts/*pathology
Hamartoma/*pathology
Humans
Lung/radiography
Lung Diseases/*pathology
Male
Tomography, X-Ray Computed

Figure

• 

  Fig. 1 Chest computed tomography reveals a huge multiseptated cystic and solid mass containing foci of intralesional calcifications in the left lower lobe of the lung.

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  Fig. 2 (A) Gross photograph of the lower lobe of left lung shows a large cystic and solid mass containing variable size of multilocular cysts and solid component with numerous interstitial cartilaginous small nodules. (B) Multilocular cystic spaces with intervening lobulated fragments of cartilaginous tissue and hyalinized stroma (H&E stain, original magnification ×1). (C) There are islands of mature cartilage, adipose tissues and immature mesenchymal tissue containing spindle cells within the intervening stroma (H&E stain, original magnification ×100).

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