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Updates of the current screening guidelines for the early detection of cervical cancer

Hong JH, Lee JK

No abstract available.
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Bevacizumab and oral metronomic cyclophosphamide in platinum-resistant ovarian cancer

Pujade-Lauraine E

No abstract available.
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The course of fatigue in patients with gynecologic and breast cancer

Vollrath M, Zenger M, Singer S, Einenkel J, Hinz A

OBJECTIVE: The objective of this study is to examine the course of fatigue in female cancer patients during the first months after treatment. METHODS: We examined a sample of 110 patients...
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Neoadjuvant chemotherapy followed by fertility-sparing surgery for women with stage IB1 cervical cancer

Wang D, Yang J, Shen K, Xiang Y

Fertility-sparing surgery was optimal to patients with tumor diameter smaller than 2 cm. For patients with larger tumors, neoadjuvant chemotherapy can debulk the tumor and offer the chance of surgery....
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Prognostic factors associated with local recurrence in squamous cell carcinoma of the vulva

Iacoponi S, Zapardiel , Diestro MD, Hernandez , De Santiago J

OBJECTIVE: To analyze the prognostic factors related to the recurrence rate of vulvar cancer. METHODS: Retrospective study of 87 patients diagnosed of vulvar squamous cell carcinoma diagnosed at a tertiary hospital...
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Thrombin promotes epithelial ovarian cancer cell invasion by inducing epithelial-mesenchymal transition

Zhong YC, Zhang T, Di W, Li WP

OBJECTIVE: Over-expression of thrombin in ovarian cancer cells is associated with poor prognosis. In this study, we investigated the role of thrombin in inducing epithelial-mesenchymal transition (EMT) in SKOV3 epithelial...
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The combination of intravenous bevacizumab and metronomic oral cyclophosphamide is an effective regimen for platinum-resistant recurrent ovarian cancer

Barber EL, Zsiros E, Lurain JR, Rademaker , Schink JC, Neubauer N

OBJECTIVE: To determine the efficacy, progression-free survival (PFS) and overall survival (OS) for the combination of intravenous bevacizumab and oral cyclophosphamide in heavily pretreated patients with recurrent ovarian carcinoma. METHODS: A...
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Prognostic factors and treatment outcome after radiotherapy in cervical cancer patients with isolated para-aortic lymph node metastases

Jang H, Chun M, Cho O, Heo JS, Ryu HS, Chang SJ

OBJECTIVE: The purpose of the present study was to evaluate treatment outcomes and prognostic factors in cervical cancer patients with isolated para-aortic lymph node (PALN) metastases. We especially tried to...
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Selective cyclooxygenase inhibitors increase paclitaxel sensitivity in taxane-resistant ovarian cancer by suppressing P-glycoprotein expression

Lee JP, Hahn HS, Hwang SJ, Choi JY, Park JS, Lee IH, Kim TJ

OBJECTIVE: The purpose of this study was to investigate whether selective cyclooxygenase (COX) inhibitors promote paclitaxel-induced apoptosis in taxane-resistant ovarian cancer cells by suppressing MDR1/P-glycoprotein (P-gp) expression. METHODS: Taxane-resistant ovarian cancer...
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p16INK4a immunohistochemistry is a promising biomarker to predict the outcome of low grade cervical intraepithelial neoplasia: comparison study with HPV genotyping

Nishio S, Fujii T, Nishio H, Kameyama K, Saito M, Iwata T, Kubushiro , Aoki D

OBJECTIVE: In cervical intraepithelial neoplasia (CIN), p16INK4a immunohistochemistry has been reported to be a useful diagnostic biomarker. However, limited information is available about the association between the p16INK4a immunohistochemistry and...
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Multivariate prognostic analysis of adenocarcinoma of the uterine cervix treated with radical hysterectomy and systematic lymphadenectomy

Kato T, Watari H, Takeda M, Hosaka M, Mitamura T, Kobayashi , Sudo S, Kaneuchi M, Kudo M, Sakuragi N

OBJECTIVE: The aim of this study was to investigate the prognostic factors and treatment outcome of patients with adenocarcinoma of the uterine cervix who underwent radical hysterectomy with systematic lymphadenectomy. METHODS:...
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Disease progression and recurrence in women treated for vulvovaginal intraepithelial neoplasia

Fehr MK, Baumann M, Mueller M, Fink D, Heinzl S, Imesch P, Dedes K

OBJECTIVE: The malignant potential of intraepithelial neoplasia of the vulva and vagina after treatment is not well defined. Our objective was to examine risk factors for recurrence and invasive disease. METHODS:...
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Ovarian cancer mortality among women aged 40-79 years in relation to reproductive factors and body mass index: latest evidence from the Japan Collaborative Cohort study

Khan MM, Khan A, Nojima M, Suzuki S, Fujino Y, Tokudome S, Tamakoshi , Mori M, Tamakoshi

OBJECTIVE: This study mainly aimed to investigate the association of ovarian cancer mortality with reproductive factors and body mass index among Japanese women aged 40-79 years. METHODS: The source of the...
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