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Recurrent Cerebral Venous Thrombosis Associated with Elevated Factor VIII

Kim MJ, Cho AH, No YJ, Kim HY, Kim JS

Cerebral venous thrombosis (CVT) rarely recurs, and the factors associated with a recurrence remain unclear. Recently, however, elevated plasma coagulation factor VIII has been considered a factor related to recurrent...
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Downbeat, Positional, and Perverted Head-Shaking Nystagmus Associated with Lamotrigine Toxicity

Oh SY, Kim JS, Lee YH, Lee AY, Kim J, Kim JM

Lamotrigine is an effective antiepileptic drug with few adverse effects. Nystagmus is one of the commonly observable signs of lamotrigine overdose, which may result from central nervous system involvement. However,...
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Ergotism With Ischemia In All Four Extremities: A Case Report

Jeong SY, Lim ES, Shin BS, Seo MW, Kim YH, Kwak HS, Chung GH, Jeong SK

Here we describe a case of ergotism that presented with ischemia in all four extremities. A 48-year-old man was admitted for pain and weakness in both upper extremities. He had...
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Opalski's Syndrome with Cerebellar Infarction

Kim HY, Koh SH, Lee KY, Lee YJ, Kim SH, Kim J, Kim HT

A 64-year-old man presented with sudden onset of right-sided hemiparesis, headache, gait disturbance, and recurrent vomiting. A physical examination revealed right-sided hemiparesis, right Horner syndrome, ataxia of the right limbs,...
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Unilateral Epileptic Negative Myoclonus Following Focal Lesion of the Postcentral Cerebral Cortex Due to Acute Middle Cerebral Infarction

Song IU, Lee DG, Kim JS, An JY, Lee SB, Kim YI, Lee KS

Here we report a patient who suffered an acute infarction of the contralateral postcentral cerebral cortex and subsequently developed unilateral partial epilepsy with negative myoclonus. The findings of brain magnetic...
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Episodic Ataxia Type 2 due to a Deletion Mutation in the CACNA1A Gene in a Korean Family

Kim JM, Kim JS, Ki CS, Jeon BS

Episodic ataxia type 2 (EA-2) is an inherited disorder that is characterized by intermittent vertigo, ataxia, and interictal gaze-evoked nystagmus. Although abnormalities associated with this disorder have been found in...
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Reflex Epilepsy Induced by Playing Oriental Card or Board Games

Lee SA, Choi EJ, Kang JK

BACKGROUND AND PURPOSE: There are currently few studies on clinical profiles of reflex epilepsy induced by thinking and spatial tasks. We studied the clinical characteristics of reflex epilepsy induced by...
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Optic Aphasia: A Case Study

Kwon M, Lee JH

Optic aphasia is a rare syndrome in which patients are unable to name visually presented objects but have no difficulty in naming those objects on tactile or verbal presentation. We...
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1alpha,25-Dihydroxyvitamin D3 Protects Dopaminergic Neurons in Rodent Models of Parkinson's Disease through Inhibition of Microglial Activation

Kim JS, Ryu SY, Yun I, Kim WJ, Lee KS, Park JW, Kim YI

BACKGROUND: Recent studies have demonstrated the molecular basis of the immunomodulatory and anti-inflammatory activities of 1,25-dihydroxyvitamin D3(1,25-(OH)2D3). This hormone improves behavioral deficits and normalizes the nigral dopamine levels in animal...
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The Effect of Paroxetine on the Reduction of Migraine Frequency is Independent of Its Anxiolytic Effect

Park HJ, Lee ST, Shim JY, Kim B, Hwang SH, Kim SH, Park JE, Park JH, Jung SH, Ahn JY, Chu K, Kim M

BACKGROUND AND PURPOSE: Anxiety is the most important precipitating factor of migraine attacks, and more than half of migraineurs have coexisting anxiety disorders. Paroxetine, an antidepressant, is one of the...
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Reliability and Validity of the Korean Version of QOLIE-10 in Epilepsy

Lee SA, Yun SC, Lee BI, Korean QoL in Epilepsy Study Group

BACKGROUND AND PURPOSE: It is necessary in clinical practice to screen patients with epilepsy for quality-of-life factors. The purpose of this study was to develop a Korean version of the...
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Preliminary Studies on the Clinical Features of Multiple Sclerosis in Korea

Lee SS, Sohn EH, Nam SW

BACKGROUND AND PURPOSE: Multiple sclerosis (MS) in Asians is characterized by frequent involvement of the spinal cord and optic nerve and low prevalence rates, but even the most fundamental epidemiologic...
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Subtyping of Ischemic Stroke Based on Vascular Imaging: Analysis of 1,167 Acute, Consecutive Patients

Kim JT, Yoo SH, Kwon JH, Kwon SU, Kim JS

BACKGROUND AND PURPOSE: Knowledge of a patient's cerebral vascular status is essential for accurately classifying stroke. However, vascular evaluations have been incomplete in previous studies, and a stroke registry based...
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Therapeutic Strategies in Huntington's Disease

Kanazawa I

This article provides an overview of the therapeutic strategies, from ordinary classical drugs to the modern molecular strategy at experimental level, for Huntington's disease. The disease is characterized by choreic...
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