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Herpesviral Interaction with Autophagy

Liang C

Autophagy constitutes a major catabolic hub for the quality control of intracellular entities of eukaryotic cells, and is emerging as an essential part of the host antiviral defense mechanism. However,...
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Cell Death and Immunity

Lee EJ, Cho JA, Seong SY

Dying cells interact with living cells and release molecules that can signal to immune system. Based on the morphology of the dying cells, there are three types of cell death,...
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Systemic Review for Efficacy of Human Papillomavirus Vaccines

Park HS

Two human papillomavirus (HPV) vaccines (Gardasil(R) and Cevarix(TM)) were launched between 2006~2007. Clinical trials have been performed in several countries. However, it takes few decades to measure HPV vaccine efficacy...
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Genetic Characterization of Norovirus GII.3 Circulating in Korea

Kim J, Park K

Noroviruses (NoV) are the major viral pathogen that causes epidemic acute gastroenteritis and outbreaks of food-borne illness. The major genotypes responsible for the epidemics of NoV are GII.4 and GII.3....
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Toll-like Receptors and Innate Immunity

Yuk JM, Jo EK

Toll-like receptors (TLRs) are the best-characterized membrane-bound receptors in innate immune cells, including macrophages and dendritic cells. Upon recognition of specific ligands originating from pathogen- and modified self-derived molecules, TLRs...
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Molecular Epidemiology of Legionella pneumophila Isolated from Bath Facilities of Public Establishments in Seoul

Jeon SJ, Jung JH, Jin YH, Lee JK, Oh YH, Choi SM

The genus Legionella is common in aquatic environments. Some species of Legionella are recognized as potential opportunistic pathogens for human, notably Legionella pneumophila that causes Legionellosis. During the summer season...
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Sequencing and Molecular Characterization of the Genome of Echovirus 30 Isolated from a Korean Aseptic Meningitis Patient

Kim J, Baek K

Echovirus 30 is one of the distinct serotypes of enteroviruses and commonly isolated agent causing sporadic to large outbreaks with aseptic meningitis in many regions over the world. Recently, an...
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Exploitation of Culture Medium for Mycobacterium tuberculosis

Kim H, Ryoo S

The culture media for Mycobacterium tuberculosis (MTB) were contrived from both egg-based and agar based ingredients. In 1903, Dorset introduced the first egg-based medium. It was followed by the invention...
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Isolation and Antimicrobial Susceptibility of Mupirocin-Resistant and Methicillin-Resistant Staphylococcus aureus from Clinical Samples

Kim SM, Park SY, Park SD

Resistance to mupirocin in methicillin-resistant Staphylococcus aureus (MRSA) have increased with wide use of mupirocin in many countries, but the prevalence in Korea is not well-known. The aim of this...
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Escherichia coli pap Genes as well as Adenovirus Type 11 and Type 21, and BK Virus were Involved with Severe Urinary Tract Infection in Infants

Park HK, Woo SY, Lee EO, Cha JE, Lee KE, Park H, Lee SJ

In infants, urinary tract infections (UTIs) are quite common and primarily caused by bacterial pathogens. However, little research has been conducted regarding the relationship between uropathogenic bacteria, virulent genes, and...
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Purification and Characterization of Helicobacter pylori gamma-Glutamyltranspeptidase

Song JY, Choi YJ, Kim JM, Kim YR, Jo JS, Park JS, Park HJ, Song YG, Lee KH, Kang HL, Baik SC, Youn HS, Cho MJ, Rhee KH, Lee WK

Gamma-glutamyltranspeptidase (GGT) was purified to electrophoretic homogeneity from the cell extract of H. pylori. The purified enzyme consisted of heavy and light subunits with molecular weights of 38 kDa and...
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Comparison of Proteome Components of Helicobacter pylori Before and After Mouse Passage

Lee KJ, Kim BR, Cho YA, Song YG, Song JY, Lee KH, Kang HL, Baik SC, Cho MJ, Rhee KH, Seo JH, Youn HS, Lee WK

The mouse model is alleged to be a useful tool for understanding of pathophysiological roles of Helicobacter pylori in the development of gastric disorders. However, it has been observed that...
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