J Bacteriol Virol.  2011 Dec;41(4):309-311. 10.4167/jbv.2011.41.4.309.

Cell Death and Immunity

• Lee EJ
• Cho JA
• Seong SY

• KMID: 2168659
• DOI: http://doi.org/10.4167/jbv.2011.41.4.309

Abstract

Dying cells interact with living cells and release molecules that can signal to immune system. Based on the morphology of the dying cells, there are three types of cell death, which are apoptotic cell death (Type I), autophagic cell death (Type II) and necrotic cell death (Type III). The immune response is different according to the pathway of cell death as apoptosis or necrosis regulates immune response via caspase activation or cytokine secretion, respectively. Here, we discuss the different modes of cell death and the nature of the immune response elicited by the released molecules from the cell death.

Keyword

Cell death; Apoptosis; Necrosis; Authophagy; Immunity

MeSH Terms

Apoptosis
Autophagy
Cell Death
Immune System
Necrosis

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