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Cell Death and Immunity

Lee EJ, Cho JA, Seong SY

Dying cells interact with living cells and release molecules that can signal to immune system. Based on the morphology of the dying cells, there are three types of cell death,...
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Cell Death and Bacterial Infection

Song CH

Cells can die through various biochemical pathways related to complex pathophysiological process. Different types of cell death are closely associated with microbial infection. Several regulatory mechanisms of cell death during...
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The Protective Role of Estrogen by Down -regulation of Bax in Ceramide Induced Neuronal Cell Death

Chae HS, Kim SS, Kim KY, Lee WB

  • KMID: 2092798
  • Korean J Anat.
  • 2002 Dec;35(6):509-516.
In the present study, we investigated effects of estrogen on cell death induced by ceramide in human neuroblastoma SK -N -SH. Estrogen, attenuated ceramide -induced cell death. To determine the...
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Epilepsy and Programmed Cell Death

Seo DW

  • KMID: 2053701
  • Hanyang Med Rev.
  • 2006 Feb;26(1):52-60.
Epilepsy is one of the most common episodic neurological diseases characterized by recurrent epileptic seizures. The seizures occur by synchronization of a neuronal network, which may cause disturbances in intracellular...
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Cell Beath Induced by Ethanol : Prevention of Cell Death by the bcl-2 Proto-Oncogene

Lim EJ, Hong KJ, Yang BH, Chai YG

  • KMID: 2202982
  • J Korean Soc Biol Psychiatry.
  • 1997 Nov;4(2):211-218.
The Bcl-2 protein has been shown to block apoptosis induced by a variety of stimuli. We have performed the experiments which cell death can be blocked by the bcl-2 proto-oncogene...
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Sonication Induces Apoptosis in HL-60 Cells

Choi M, Seo I, Suh SI, Suh MH, Baek WK

To investigate a specific mechanism of apoptosis induced by sonication, we applied 20 kHz ultrasound to leukemia cell line HL-60 with different intensities (0-60 W/cm2) and time durations (0-100 sec)....
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Chrysophanic Acid Induces Necrosis but not Necroptosis in Human Renal Cell Carcinoma Caki-2 Cells

Choi JS

BACKGROUND: Chrysophanic acid, also known as chrysophanol, has a number of biological activities. It enhances memory and learning abilities, raises superoxide dismutase activity, and has anti-cancer effects in several model...
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Neuronal Change in the Dentate and Hippocampus of Adrenalectomized and Adrenal Corticosteroid Injected Neonatal Rats

Kim KY, Choi KA, Lee WB

The influences of adrenal corticosteroid on the development and regression of neurons of dentate and hippocampus were studied by adrenalectomy and steroid overload in neonatal rats. The results obtained were...
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Caspase is Regulated by ROS in CT Induced Neuronal Cell Death

Chae HS, Suh YH, Kim KY, Lee WB, Kim SS

  • KMID: 1514935
  • Korean J Anat.
  • 2003 Apr;36(2):133-140.
Carboxy-terminal fragment of amyloid precusor protein (CT) is a candidate of causal molecule in the pathogenesis of Alzheimer's disease. Although it has been identified that CT shows cytotoxicity in various...
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Death and Survival of Cardiomyocytes in Acute Ischemia

Lee SH, Kim YD

Ischemia is the most common and important cause of injury to cardiomyocytes. Acute ischemia causes profound derangement of the cellular energetics and metabolism, and this ultimately leads to cell death....
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Curcumin-Induced Autophagy Augments Its Antitumor Effect against A172 Human Glioblastoma Cells

Lee JE, Yoon SS, Moon EY

Glioblastoma is the most aggressive common brain tumor in adults. Curcumin, from Curcuma longa, is an effective antitumor agent. Although the same proteins control both autophagy and cell death, the...
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Effect of MK801 and CNQX on Retinal Injury Induced by Ischemia, NMDA, or Kainate

Choi JS, Gwag BJ, Yoon SK, Joo CK

  • KMID: 2108525
  • J Korean Ophthalmol Soc.
  • 1998 Aug;39(8):1794-1800.
To examine the protection of retinal cell death by glutamate antagonists in vivo, this study was carried out in pressure-induced ischemia model. Firstly, we observed that ischemia resulted in the...
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Cell Death Induction Mechanism of Non-small Cell Lung Cancer Cell Line, NCI-H1703 by Docetaxel

Ha HC, Kim YD, Song SH, Park CS, Kim JW

  • KMID: 1878599
  • Korean J Thorac Cardiovasc Surg.
  • 2006 Sep;39(9):668-673.
BACKGROUND: Docetaxel has been effectively used as an anti-cancer chemotherapuetic agent for various tumor treatments including lung cancer. However, the cell death induction mechanism(s) involved with docetaxel treatment in lung...
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Modulation of irradiation-induced cell death by insulin-like growth factor-ii in MC3T3 osteoblasts

Park KL

  • KMID: 1814526
  • J Korean Assoc Oral Maxillofac Surg.
  • 2007 Dec;33(6):617-624.
Insulin-like growth factor (IGF) is the most abundant growth factor in bone matrix. Recent studies have shown that it can sensitize apoptotic cell death of osteoblasts. Thus, this study investigated...
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Effects of Cycloheximide and Dexamethasone on Fas - Mediated Apopthsis in Primary Human Astrocytes

Choi C, Choi IH, Huh K

  • KMID: 1550755
  • Korean J Immunol.
  • 1999 Dec;21(4):361-368.
Astrocytes are major glial cells in central nervous system (CNS) and are known to express death receptors or ligands that can induce apoptosis of astrocytes or other brain cells. We...
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mechanism of Cell Death induced by ZnCl2 and Calmodulin Antagonist in Human Retinoblastoma Cells

Joung HJ, Eum YH, Park HT, Yun IH

  • KMID: 2124592
  • J Korean Ophthalmol Soc.
  • 2000 Dec;41(12):2686-2698.
No Abstract Available.
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Cell-in-Cell Death Is Not Restricted by Caspase-3 Deficiency in MCF-7 Cells

Wang S, He M, Li L, Liang Z, Zou Z, Tao A

PURPOSE: Cell-in-cell structures are created by one living cell entering another homotypic or heterotypic living cell, which usually leads to the death of the internalized cell, specifically through caspase-dependent cell...
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TRAIL-induced cell death and caspase-8 activation are inhibited by cisplatin but not carboplatin

Han SJ, Ahn TK, Choi HS, Shin JN, Piya S, Kim TH

OBJECTIVE: Platinum (Pt) based drugs including cisplatin and carboplatin are widely used as anticancer drugs in various human cancers. Many studies have shown that chemotherapeutic agents synergistically enhance cell death...
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Eosinophil Apoptosis

Park YM

  • KMID: 2315030
  • Pediatr Allergy Respir Dis.
  • 2010 Dec;20(4):219-225.
Eosinophilia is common feature in many diseases, including allergic diseases. There are many factors involved in the survival and the death of eosinophil. Apoptosis is the most common form of...
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Molecular Aspects of Radiotherapy

Park HJ

  • KMID: 2200190
  • J Lung Cancer.
  • 2003 Mar;2(1):10-15.
When tumor cells are exposed to ionizing radiation, various and complicated molecular biological changes take place leading to cell death, mutation, and recovery from sublethal damage. It has been known...
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