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Development of UPSR Primer Design Program for Efficient Detection of Viruses

Jang SY, Yoon HW, Oh SA, Lee KM, Lee CH

PCR is a rapid and sensitive method for detection of viruses from clinical samples and good primers are essential for successful PCR. However, high mutation rate of viral genomes often...
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Molecular Epidemiologic Investigation of Norovirus Infections in Incheon City, Korea, from 2005 to 2007

Gong YW, Oh BY, Kim HY, Lee MY, Kim YH, Go JM, Lee JM, Jeong HS, Cheon DS

Noroviruses (NoVs) cause major epidemic gastroenteritis in humans. To obtain the molecular epidemiological information on gastroenteritis sporadic cases in Incheon city, Korea, we analyzed the nucleotide sequences of NoV strains...
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Expression of Plus- and Minus-strand Viral RNA in Coxsackievirus B3-Infected A/J Mice

Hwang IS, Jun EJ, Ye JS, Joo CH, Lee H, Kim YK

In order to investigate the implication of viral replication in acute, subacute, and chronic infections of coxsackievirus B3 (CVB3), we examined the histopathological changes and plus- and minus-strand viral RNA...
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Purification of Protein Expressed from Three Different Regions of Norovirus (NoV)

Kim JY, Choi JW, Park SW, Lee SG, Kim JM, Jheong WH, Kim DW, Kim JM, Sohn YS, Paik SY

Norovirus (NoV), which belongs to the family Caliciviridae, is one of the major causes of nonbacterial acute gastroenteritis in the world. In this study, we purified proteins from the epitope...
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Expression of CCL18 (Dendritic Cell-Derived Chemokine) mRNA in Gastric Mucosa Infected with Helicobacter pylori

Park HY, Jo EK, Kim HJ, Park JK

Helicobacter pylori (H. pylori) is a major etiologic agent causing chronic gastritis, along with other features, including lymphoid follicles, surface epithelial degeneration with mucous depletion and intestinal metaplasia. To clarify...
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Rapid Identification of Rickettsiae using the Real-Time PCR

Park HS, Lee JH, Jin KH, Jang WJ, Park KH, Kook YH, Lee SH

In this study, new real-time PCR method based on the groEL gene was developed and investigated. Four spotted fever group (SFG) strains, four typhus group (TG) strains, and four scrub...
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Cytolethal Distending Toxin Production, Genotypes and Atimicrobial Susceptibility of Campylobacter jejuni Isolates from Diarrhea Patients and Chickens

Kim SM, Kim EC, Choi MR, So HA, Shim ES, Kim ES, Park SC, Seong CN, Chong Y

Campylobacter jejuni isolates from diarrhea patients and chickens in 2008 in Iksan, Korea were tested for biochemical characteristics, and for possession of genes hipO, mutated gyrA, and cdtB. Among the...
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Effects of Biofilm Formation on The Antimicrobial Susceptibility of Staphylococcus aureus

Cho KJ, Jin S, Cui J, Yoon TR, Ryu PY

Staphylococcus aureus induces chronic infection in form of biofilm that exists in the host cells and arthroplastic prosthesis surface. In this study, the biofilm formation ability of S. aureus clinically...
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Detection of Virulence Genes of Staphyloccus aureus and Staphylococcus epidermidis Isolated from Suprapubic Urine from Infants with Fever

Park HK, Woo SY, Jung YJ, Lee EO, Cha JE, Park HS, Lee SJ

While methicillin-resistant Staphylococcus aureus (MRSA) isolated from urinary tract infection (UTI) has recently increased in elderly adult urology patients, it has been only rarely reported in infants. Therefore, in this...
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Epidemiological Prevalence of Avian Pathogenic Escherichia coli Differentiated by Multiplex PCR from Commercial Chickens and Hatchery in Korea

Kwon SG, Cha SY, Choi EJ, Kim B, Song HJ, Jang HK

We examined 216 Escherichia coli (E. coli) isolated from chickens and environmental specimens from hatcheries between 2005 and 2006 in order to evaluate the epidemiological prevalence of avian pathogenic E....
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Patterns of Helicobacter pylori Resistance to Metronidazole, Clarithormycin and Amoxicillin in Saudi Arabia

Marie MA

There are no generally accepted regimens for the treatment of H. pylori infection in patients with gastritis or duodenal ulcers. However, metronidazole based regimens have been reported to be among...
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Production and Quality Control of Adenoviral Vectors for Clinical Trials

Park SW, Sohn YS, Paik SY

The importance of recombinant adenoviral vectors for the development of gene therapy and prophylactic and therapeutic vaccines has led to efforts for process development of large scale production of clinically...
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