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Succinate-treated macrophages attenuate dextran sodium sulfate colitis in mice

Park IS, Son M, Ma HW, Kim J, Kim DH, Kim SW, Cheon JH

Background/Aims: The safety and effectiveness of adalimumab was demonstrated in a phase 3 trial in Japanese patients with intestinal Behçet’s disease. The aim of this study was to evaluate the...
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Is adalimumab safe and effective in patients with intestinal Behcet’s disease in real-world practice?

Suzuki Y, Hagiwara T, Kobayashi M, Morita K, Shimamoto T, Hibi T

Background/Aims: The safety and effectiveness of adalimumab was demonstrated in a phase 3 trial in Japanese patients with intestinal Behçet’s disease. The aim of this study was to evaluate the...
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Effect of resistance exercise training on Crohn’s disease patients

Papadimitriou K

Crohn’s disease (CD) is observed with increased levels of cytokines which cause inflammation in many parts of the digestive tract. Aerobic exercise contributes to the reduction of the intestine’s inflammation...
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Gastrointestinal tract diseases as a risk factor for SARSCoV2 rectal shedding? An Italian report on 10 COVID-19 patients

Patrì A, Pinchera B, Spirito L, Delfino M, Imbimbo C, Salvatore P, Gentile I, Fabbrocini G

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Management of Clostridioides difficile infection in patients with inflammatory bowel disease

Khanna S

Inflammatory bowel disease (IBD) is a common diarrheal illness with gastrointestinal and extraintestinal manifestations and complications. The most common infectious complication associated with IBD is Clostridioides difficile infection (CDI). Active...
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Effect of gut microbiome on minor complications after a colonoscopy

Kim JH, Choi YJ, Kwon HJ, Jung K, Kim SE, Moon W, Park MI, Park SJ

Background/Aims: Minor complications that might occur after colonoscopy, including abdominal discomfort, bloating, diarrhea, and constipation, could a barrier for patients to undergo a screening colonoscopy. In this study, we aimed...
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Correlation of serum levels of anti-tumor necrosis factor agents with perianal fistula healing in Crohn’s disease: a narrative review

Miranda EF, Nones RB, Kotze PG

With the overspread use of measurement of serum levels of anti-tumor necrosis factor (TNF) agents (therapeutic drug monitoring, TDM), new therapeutic strategies have been used in the management of Crohn’s...
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Trends of inflammatory bowel disease at a tertiary care center in northern India

Sood A, Kaur K, Singh A, Midha V, Mahajan R, Bansal N, Mehta V, Singh D

Background/Aims: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), is increasingly being reported from India and other Asian countries. This study looks into the changing trends...
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Long-term outcomes of infliximab in a real-world multicenter cohort of patients with acute severe ulcerative colitis

Oh SJ, Shin GY, Soh H, Lee JG, Im JP, Eun CS, Lee KM, Park DI, Han DS, Kim HJ, Lee CK

Background/Aims: Infliximab (IFX) has proven effective as rescue therapy in steroid-refractory acute severe ulcerative colitis (ASUC), however, the long-term real-world data are scarce. Our study aimed to assess the long-term...
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Efficacy and tolerability of exclusive enteral nutrition in adult patients with complicated Crohn’s disease

Sharma S, Gupta A, Kedia S, Agarwal S, Singh N, Goyal S, Jain S, Gupta V, Sahu P, Vuyyuru SK, Kante B, Sharma R, Panwar R, Sahni P, Makharia G, Ahuja V

Background/Aims: Exclusive enteral nutrition (EEN), an established modality for pediatric Crohn’s disease (CD) is seldomly utilized in adults. The present study reports the outcome of EEN in adult CD patients...
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Incidence and risk factors for venous thrombosis among patients with inflammatory bowel disease in China: a multicenter retrospective study

Liu J, Gao X, Chen Y, Mei Q, Zhu L, Qian J, Hu P, Cao Q

Background/Aims: Risk of venous thrombosis is increased in patients with inflammatory bowel disease (IBD); data on Asian IBD patients is limited and status quo of thrombosis screening and prophylaxis are...
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Patterns of endoscopy during COVID-19 pandemic: a global survey of interventional inflammatory bowel disease practice

Chen Y, Yu Q, Farraye FA, Kochhar GS, Bernstein CN, Navaneethan U, Wu K, Zhong J, Schwartz DA, Wu H, Zheng JJ, Iacucci M, Kiran RP, Shen B

Background/Aims: Performance of diagnostic or therapeutic endoscopic procedures in inflammatory bowel disease (IBD) patients can be challenging during a viral pandemic; the main concerns being the safety and protection of...
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