- Crosstalk between Signaling Pathways and Energy Metabolism in Pluripotency
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Kim KT, Kim SM, Cha HJ
- KMID: 2565193
- Int J Stem Cells.
- 2025 Feb;18(1):12-20.
- doi: 10.15283/ijsc23173
The sequential change from totipotency to multipotency occurs during early mammalian embryo development. However, due to the lack of cellular models to recapitulate the distinct potency of stem cells at... -
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- Probiotic-Derived P8 Protein: Promoting Proliferation and Migration in Stem Cells and Keratinocytes
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Jang SB, Kim Y, Yeo HC, Kang GH, An BC, Ryu Y, Chung MJ, Cho SG
- KMID: 2565199
- Int J Stem Cells.
- 2025 Feb;18(1):87-98.
- doi: 10.15283/ijsc24107
Probiotics exert various effects on the body and provide different health benefits. Previous reports have demonstrated that the P8 protein (P8), isolated from Lactobacillus rhamnosus, has anticancer properties. However, its... -
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- The Differential Developmental Neurotoxicity of Valproic Acid on Anterior and Posterior Neural Induction of Human Pluripotent Stem Cells
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Kim J, Park SH, Sun W
- KMID: 2565196
- Int J Stem Cells.
- 2025 Feb;18(1):49-58.
- doi: 10.15283/ijsc24066
Valproic acid (VPA), widely used as an antiepileptic drug, exhibits developmental neurotoxicity when exposure occurs during early or late pregnancy, resulting in various conditions ranging from neural tube defects to... -
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- Stem Cell-Based Approaches in Parkinson’s Disease Research
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Kim MS, Yoon S, Choi J, Kim YJ, Lee G
- KMID: 2565194
- Int J Stem Cells.
- 2025 Feb;18(1):21-36.
- doi: 10.15283/ijsc23169
Parkinson’s disease (PD) is a neurodegenerative condition characterized by the loss of midbrain dopaminergic neurons, leading to motor symptoms. While current treatments provide limited relief, they don’t alter disease progression.... -
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- Assessment of the Therapeutic Effectiveness of Glutathione-Enhanced Mesenchymal Stem Cells in Rat Models of Chronic Bladder Ischemia-Induced Overactive Bladder and Detrusor Underactivity
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Shin JH, Yu HY, Kwon H, Yun HD, Ryu CM, Shin DM, Choo MS
- KMID: 2565198
- Int J Stem Cells.
- 2025 Feb;18(1):72-86.
- doi: 10.15283/ijsc23147
Overactive bladder (OAB) and detrusor underactivity (DUA) are representative voiding dysfunctions with a chronic nature and limited treatment modalities, and are ideal targets for stem cell therapy. In the present... -
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- Applications of Single-Cell Omics Technologies for Induced Pluripotent Stem Cell-Based Cardiovascular Research
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Kim H, Choi S, Heo H, Cho SH, Lee Y, Kim D, Jung KO, Rhee S
- KMID: 2565195
- Int J Stem Cells.
- 2025 Feb;18(1):37-48.
- doi: 10.15283/ijsc23183
Single-cell omics technologies have transformed our investigation of genomic, transcriptomic, and proteomic landscapes at the individual cell level. In particular, the application of single-cell RNA sequencing has unveiled the complex... -
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- The Effect of Nerve Growth Factor on Cartilage Fibrosis and Hypertrophy during In Vitro Chondrogenesis Using Induced Pluripotent Stem Cells
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Jung SI, Choi SH, Kim JW, Lim J, Rim YA, Ju JH
- KMID: 2565197
- Int J Stem Cells.
- 2025 Feb;18(1):59-71.
- doi: doi.org/10.15283/ijsc24097
Nerve growth factor (NGF) is a neurotrophic factor usually involved in the survival, differentiation, and growth of sensory neurons and nociceptive function. Yet, it has been suggested to play a... -
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- Lung Cancer Organoid System to Evaluate the Cytotoxicity of Natural Killer Cells
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Oh B, Kim J, Kim N, Jeong Y
- KMID: 2565200
- Int J Stem Cells.
- 2025 Feb;18(1):99-106.
- doi: 10.15283/ijsc24021
Natural killer (NK) cells are gaining growing attention due to their promise for immunotherapy. A fast and accurate system is needed to test NK cell biology and their therapeutic application.... -
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- Immune-Epithelial Cell Interactions during Epidermal Regeneration, Repair, and Inflammatory Diseases
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Schmitter-Sánchez AD, Park S
- KMID: 2565192
- Int J Stem Cells.
- 2025 Feb;18(1):1-11.
- doi: 10.15283/ijsc23107
The multiple layers of the skin cover and protect our entire body. Among the skin layers, the epidermis is in direct contact with the outer environment and serves as the... -
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