- Thapsigargin Increases IL-2 Production in T Cells at Nanomolar Concentrations
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Kim KH, Kim SH, Jung HH, Moon JH, Jeong SU, Yu K, Lee CK
- KMID: 2419771
- Immune Netw.
- 2018 Aug;18(4):e26.
- doi: 10.4110/in.2018.18.e26
Thapsigargin (TGN) is a potent and selective inhibitor of sarco-endoplasmic Ca²âº-ATPase, leading to rapid elevation of cytoplasmic Ca2+ concentration. Previous reports have shown that TGN increases the production of various... -
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- Neolignan Derivatives from the Flower of Magnolia biondii Pamp. and their Effects on IL-2 expression in T-cells
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Nguyen TT, Nguyen TT, Lee HS, Jun CD, Min BS, Kim JA
- KMID: 2387062
- Nat Prod Sci.
- 2017 Jun;23(2):119-124.
- doi: 10.20307/nps.2017.23.2.119
The isolation of the MeOH extract from the flower bud of Magnolia biondii Pamp. using various column chromatographies and HPLC led to eleven neoglignan derivatives (1 - 11). Their structures... -
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- Anti-GD2 Monoclonal Antibody (dinutuximab) with GM-CSF, Interleukin 2, and Cis-retinoic Acid for the Treatment of High-risk Neuroblastoma
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Jeon IS
- KMID: 2358361
- Clin Pediatr Hematol Oncol.
- 2016 Oct;23(2):71-76.
- doi: 10.15264/cpho.2016.23.2.71
Neuroblastoma, one of the most common solid tumors in early childhood, exhibits aberrant cell-surface glycosylation patterns. In neuroblastoma, disialoganglioside (GD2) is expressed homogeneously and abundantly on 100% of neuroblastoma cells.... -
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- The Efficacy and Safety of an Immunosuppressive Regimen Including the Use of Mycophenolate Mofetil and an Interleukin-2 Monoclonal Antibody in Heart Transplant Patients
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Ahn JM, Kim JJ, Song MG, Kim HY, Lee CH, Song JK, Park SW, Park SJ, Kim IO
- KMID: 2013160
- Korean Circ J.
- 2006 Dec;36(12):794-801.
- doi: 10.4070/kcj.2006.36.12.794
BACKGROUND AND OBJECTIVES: An immunosuppressive regimen including the use of mycophenolate mofetil (MMF) and an interleukin-2 monoclonal antibody (IL2mAb) has shown promise to prevent acute rejection after heart transplantation. There... -
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- A Case of Steroid Refractory Acute GVHD Treated with IL-2 & TNF-alpha Blocker in a Myelodysplastic Syndrome Patient who Underwent Unrelated Allogeneic Stem Cell Transplantation
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Lee HH, Ahn MJ, Choi CU, Park SR, Baek YH, Sohn W, Lee DJ, Chang MH, Choi JH, Lee YY, Kim IS, Park CK
- KMID: 2252328
- Korean J Hematol.
- 2006 Mar;41(1):51-55.
- doi: 10.5045/kjh.2006.41.1.51
Hematopoietic stem cell transplantation has evolved as a central treatment modality for the management of various hematologic malignancies. Despite adequate posttransplantation immunosuppressive therapy, acute GVHD remains a major cause of... -
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- Selective Expansion of Natural Killer Cells from Peripheral Blood Mononuclear Cells by K562 Cell Line and IL-2
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Cho D, Shin SW, Park JS, Kang HK, Kim SK, Pham TN, Zhu XW, Shin MG, Suh SP, Ryang DW, Nam JH, Kim YJ, Lee JJ
- KMID: 2252322
- Korean J Hematol.
- 2006 Mar;41(1):8-15.
- doi: 10.5045/kjh.2006.41.1.8
BACKGROUND: Several attempts have been made to expand human NK cells from peripheral blood mononuclear cells (PBMCs). This study examined the selective expansion of NK cells using interleukin 2 (IL-2)... -
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- Human Activated Lymphocyte Treated with Anti-CD3, CD16, CD56 Monoclonal Antibody and IL-2
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Hong SM, Lee DW, Kang JG, Kim HS, Cho SH
- KMID: 2150584
- Immune Netw.
- 2005 Mar;5(1):11-15.
- doi: 10.4110/in.2005.5.1.11
BACKGROUND: Throughtout the last three decades, the therapy of leukemias and lymphoma has set the stage for curative cancer therapy in systemic malignant disease. This was the result of an... -
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- Effects of Enterococcus faecalis sonicated extracts on IL-2, IL-4 and TGF-beta1 production from human lymphocytes
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Kim HS, Jang SW, Shon WJ, Lee ST, Kim CH, Lee WC, Lim SS
- KMID: 1986990
- J Korean Acad Conserv Dent.
- 2005 Jan;30(1):1-6.
- doi: 10.5395/JKACD.2005.30.1.001
In order to examine the immunoresponse of host cells to Enterococcus faecalis, this in vitro study monitored the production of Interleukin-2 (IL-2), Interleukin-4 (IL-4) and Transforming growth factor-beta1 (TGF-beta1) in... -
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- Inhibition of Graft Versus Host Disease Using CD4+ CD25+ T Cells Induced with Interleukin-2 in Mismatched Allogeneic Murine Hematopoietic Stem Cell Transplantation
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Hyun JH, Jeong DC, Chung NG, Park SJ, Min WS, Kim TG, Choi BO, Kim WI, Han CW, Kim HK
- KMID: 2054233
- Immune Netw.
- 2003 Dec;3(4):287-294.
- doi: 10.4110/in.2003.3.4.287
BACKGROUND: In kidney transplantation, donor specific transfusion may induce tolerance as a result of some immune regulatory cells against the graft. In organ transplantation, the immune state arises from a... -
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- Evaluation of Tuberculosis Activity in Patients with Anthracofibrosis by Use of Serum Levels of IL-2 sRalpha, IFN-gamma and TBGL(Tuberculous Glycolipid) Antibody
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Jeong DY, Cha YJ, Lee BJ, Jung HR, Lee SH, Shin JW, Kim JY, Park IW, Choi BW
- KMID: 2318420
- Tuberc Respir Dis.
- 2003 Sep;55(3):250-256.
BACKGROUND: Anthracofibrosis, a descriptive term for multiple black pigmentation with fibrosis on bronchoscopic examination, has a close relationship with active tuberculosis (TB). However, TB activity is determined in the later... -
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- Chemotherapy and Low Dose Interleukin-2 Therapy for Acute Myeloid Leukemia in Patient with Down Syndrome
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Kim JT, Pai KS, Kim MK, Jung JW, Soh DM
- KMID: 2278233
- Korean J Pediatr Hematol Oncol.
- 2001 Apr;8(1):126-131.
A 4-day-old patient with Down syndrome (DS) visited out patient department (OPD) because of jaundice and VSD. Peripheral blood smear showed 21% of myeloblast. After 4 weeks of observation, WBC... -
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- Effects of B-16 Melanoma Cells and Mycoplasma pneumoniae on the Induction of IL-1 beta, IL-2, IL-6, IL-10, IL-12, and TNF - alpha from Mouse Astrocytes
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Kim TY, Jeon BC, Lee HD, Chang MW
- KMID: 1621372
- J Bacteriol Virol.
- 2001 Mar;31(1):1-10.
No abstract available. -
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- Combination Gene Therapy Using IL-2 and GM-CSF Genes Transferred by a Defective Infectious Single Cycle Herpes Virus (DISC Virus) in Head and Neck Squamous Cell Cancer Model
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Kim SH, Hong WP, Choi EC, Yoon JH, Choi JJ, Yoon HC
- KMID: 2275629
- Korean J Otolaryngol-Head Neck Surg.
- 2001 Jan;44(1):71-79.
BACKGROUND AND OBJECTIVES: The Herpes Simplex type 2 Defective Infectious Single Cycle virus (DISC virus) is an attenuated virus originally produced as a viral vaccine, but it also serves as... -
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- Experimental Otitis Media with Effusion Induced by Interleukin 2
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Kim BG, Park YS, Jung DG, Park SY, Yeo SW, Chae SY
- KMID: 2275620
- Korean J Otolaryngol-Head Neck Surg.
- 2001 Jan;44(1):21-25.
BACKGROUND AND OBJECTIVES: The etiology and pathogenesis of otitis media with effusion (OME) have not been fully elucidated, although multiple theories exist. These pathogenic factors are eustachian tube dysfunction, allergy,... -
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- Serum soluble IL-2 receptor levels following interferon and ribavirin combination therapy with chronic hepatitis C
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Lee JY, Yang JW, Park SH, Park CJ, Seo JS, Lee JH, Kim YB, Kim HY, Yoo JY
- KMID: 2306171
- Korean J Med.
- 2000 Nov;59(5):511-515.
BACKGROUND: To evaluate the cellular immune response to interferon(IFN)-alpha and ribavirin combination therapy in patients with chronic hepatitis C, we monitored serum levels of soluble IL-2 receptor(sIL2R) before and after... -
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- The Levels of Interferon-gamma, Interleukin-2 Receptor, Interleukin-6 and Interleukin-10 in the patients with Malignant Pleural Effusion, Tuberculosis Effusion, Parapneumonic Effusion, and Lung Emphysema?
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Kim MH, Kim SJ, Park YK, Kim SC, Lee SY, Kim YK, Kim KH, Moon HS, Song JS, Park SH
- KMID: 2160291
- Tuberc Respir Dis.
- 2000 Nov;49(5):568-575.
- doi: 10.4046/trd.2000.49.5.568
BACKGROUND: Cytokines are chemical mediators that control and modulate many infalmmatory processes. They work in different fashions in a variety of diseases. Discriminating between malignant effusion, tuberculous effusion, and parapneumonic... -
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- Expression of HLA-DR, ICAM-1, IL-2 and IL-4 in Renal Biopsy of Trasplanted Patient
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Nam ES, Lee HI, Kim DH, Shin HS, Lee S, Kim JS, Kim ST, Chae DW
- KMID: 2003712
- J Korean Soc Transplant.
- 2000 Jun;14(1):65-74.
PURPOSE: We performed this study to evaluate the value as early markers predicting the acute rejection and differential diagnosis with other causes of renal dysfunction. METHODS: Immunohistochemical stains for HLA-DR,... -
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- Effects of Low Dose Interleukin-2 Therapy after High Dose Chemotherapy and Autologous PBSCT in Childhood AML and Stage 4 Neuroblastoma
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Kim MK, Lyu CJ, Park SH, Cho HS, Yang CH, Kim HM, Kang SH, Kim KY
- KMID: 1979927
- Korean J Pediatr Hematol Oncol.
- 2000 Apr;7(1):82-91.
PURPOSE: Interleukin-2 (IL-2) exerts anti-cancer effect by increasing NK cell activity when the tumor burden is low. Earlier study conducted with high dose intravenous IL-2 exhibited significant toxicities such... -
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- Clinical applications of interleukin-2
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Lee HG
- KMID: 1551283
- Korean J Med.
- 1999 Oct;57(4):453-458.
No abstract available. -
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- Immunochemotherapy using Interleukin-2, Interferon-alpha, and 5-fluorouracil for Advanced Renal Cell Carcinoma
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Lim D, Lee SB, Kim DY, Park MS, Lee SE
- KMID: 2290365
- Korean J Urol.
- 1999 Aug;40(8):957-962.
PURPOSE: The role of immunotherapy in the treatment of patients with advanced renal cell carcinoma(RCC) is being evaluated by a number of investigators. In this study, we evaluated the efficacy... -
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