- The Role of Cyclosporine and Mycophenolate in an Orthotopic Porcine-to-Rat Corneal Xenotransplantation
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Lee HI, Kim MK, Oh JY, Ko JH, Lee HJ, Wee WR, Lee JH
- KMID: 1786890
- J Korean Med Sci.
- 2008 Jun;23(3):492-501.
- doi: 10.3346/jkms.2008.23.3.492
We performed this study to investigate the feature of rejection in porcine-to-rat corneal orthotopic transplantation and to evaluate the effect of cyclosporine and mycophenolate on the xeno-rejection. Orthotopic corneal transplantation... -
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- Effects of interleukin-10 on chemokine KC gene expression by mouse peritoneal macrophages in response to Candida albicans
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Kim HS, Shin DH, Kim SK
- KMID: 646014
- J Korean Med Sci.
- 1999 Oct;14(5):480-486.
- doi: 10.3346/jkms.1999.14.5.480
Chemokine KC has been considered to be a murine homologue of human GRO/MGSA and was identified as chemoattractant for monocytes and neutrophils. This study examined the expression of KC mRNA... -
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- Regulatory B Cells Are Inversely Associated with Disease Activity in Rheumatoid Arthritis
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Kim J, Lee HJ, Yoo IS, Kang SW, Lee JH
- KMID: 1799502
- Yonsei Med J.
- 2014 Sep;55(5):1354-1358.
- doi: 10.3349/ymj.2014.55.5.1354
PURPOSE: The function of regulatory B lymphocytes is known to be abnormal in inflammatory diseases. However, a recent study indicates that IL-10+ B cells seem to be expanded in rheumatoid... -
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- Inhibition of hepatic stellate cells by bone marrow-derived mesenchymal stem cells in hepatic fibrosis
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Jang YO, Jun BG, Baik SK, Kim MY, Kwon SO
- KMID: 2164364
- Clin Mol Hepatol.
- 2015 Jun;21(2):141-149.
- doi: 10.3350/cmh.2015.21.2.141
BACKGROUND/AIMS: Therapies involving bone-marrow-derived mesenchymal stem cells (BM-MSCs) have considerable potential in the management of hepatic disease. BM-MSCs have been investigated in regenerative medicine due to their ability to secrete... -
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- Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10
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Yang SH, Park MJ, Yoon IH, Kim SY, Hong SH, Shin JY, Nam HY, Kim YH, Kim B, Park CG
- KMID: 1123805
- Exp Mol Med.
- 2009 May;41(5):315-324.
- doi: 10.3858/emm.2009.41.5.035
Mesenchymal stem cells (MSCs) can inhibit T cell proliferation; however, the underlying mechanisms are not clear. In this study, we investigated the mechanisms of the immunoregulatory activity of MSCs on... -
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- Recent Advances in the Concept and Pathogenesis of IgG4-Related Disease in the Hepato-Bilio-Pancreatic System
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Okazaki K, Yanagawa M, Mitsuyama , Uchida K
- KMID: 2070055
- Gut Liver.
- 2014 Sep;8(5):462-470.
- doi: 10.5009/gnl14107
Recent studies have proposed nomenclatures of type 1 autoimmune pancreatitis (AIP) (IgG4-related pancreatitis), IgG4-related sclerosing cholangitis (IgG4-SC), IgG4-related cholecystitis, and IgG4-related hepatopathy as IgG4-related disease (IgG4-RD) in the hepato-bilio-pancreatic system.... -
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- Angiopoietin-1 Modified Human Umbilical Cord Mesenchymal Stem Cell Therapy for Endotoxin-Induced Acute Lung Injury in Rats
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Huang ZW, Liu N, Li D, Zhang HY, Wang Y, Liu Y, Zhang LL, Ju XL
- KMID: 2374208
- Yonsei Med J.
- 2017 Jan;58(1):206-216.
- doi: 10.3349/ymj.2017.58.1.206
PURPOSE: Angiopoietin-1 (Ang1) is a critical factor for vascular stabilization and endothelial survival via inhibition of endothelial permeability and leukocyte- endothelium interactions. Hence, we hypothesized that treatment with umbilical cord... -
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- Attenuation of Peripheral Regulatory T-Cell Suppression of Skin-Homing CD8+T Cells in Atopic Dermatitis
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Zhang BX, Lyu JC, Liu HB, Feng DQ, Zhang DC, Bi XJ, Duan ZW, Ding G
- KMID: 2352807
- Yonsei Med J.
- 2015 Jan;56(1):196-203.
- doi: 10.3349/ymj.2015.56.1.196
PURPOSE: Cutaneous lymphocyte-associated antigen (CLA)-expressing CD8+T cells have been known to play an important role in the pathogenesis of atopic dermatitis (AD). However, the mechanisms underlying the loss of self-tolerance... -
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- B cell-associated immune profiles in patients with end-stage renal disease (ESRD)
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Kim KW, Chung BH, Jeon EJ, Kim BM, Choi BS, Park CW, Kim YS, Cho SG, Cho ML, Yang CW
- KMID: 1387357
- Exp Mol Med.
- 2012 Aug;44(8):465-472.
Most of the previous studies on immune dysregulation in end-stage renal disease (ESRD) have focused on T cell immunity. We investigated B cell subpopulations in ESRD patients and the effect... -
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- Clinical Significance of Monitoring Circulating CD4+CD25+ Regulatory T Cells in Kidney Transplantation during the Early Posttransplant Period
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Kim SH, Oh EJ, Ghee JY, Song HK, Han DH, Yoon HE, Choi BS, Yoon SK, Choi JY, Moon IS, Kim DG, Yang CW
- KMID: 1778153
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S135-S142.
- doi: 10.3346/jkms.2009.24.S1.S135
The CD4+CD25+ T regulatory cells (Tregs) play an important role in immune tolerance in experimental transplantation but the clinical significance of circulating Tregs in the peripheral blood is undetermined. In... -
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