- Interferon beta-1b Treatment in a Korean Girl with Multiple Sclerosis
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Kim HJ, Kim HD, Lee JS, Kang HC
- KMID: 2329623
- J Korean Child Neurol Soc.
- 2013 Mar;21(1):28-32.
Here we report a case of pediatric multiple sclerosis treated with interferon beta-1b. Interferon beta is widely used in adult patients with multiple sclerosis (MS). However, its effects and safety... -
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- Interferon-beta Induced Skin Necrosis
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Bae GY, Chung YI, Park KI, Lee MW, Moon KC, Koh JK
- KMID: 2362398
- Ann Dermatol.
- 2003 Sep;15(3):119-121.
- doi: 10.5021/ad.2003.15.3.119
Local cutaneous reactions have been reported at injection sites of interferon therapy, but these are usually erythema or rarely induration. Skin necrosis at the injection site is rare. We describe... -
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- Reduction of Disease Activity in Patient with Relapsing-Remitting Multiple Sclerosis after Switching to Teriflunomide from Interferon Beta
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Shin KS, Park JG, Park MS
- KMID: 2153170
- J Korean Neurol Assoc.
- 2016 Feb;34(1):77-79.
- doi: 10.17340/jkna.2016.1.17
No abstract available. -
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- Sporadic Porphyria Cutanea Tarda in a Patient with Multiple Sclerosis Treated with Interferon Beta 1-a Therapy: A Case Report
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Carrieri P, Petracca M, Montella S, Cerullo G, Cerillo I, Cimmino G
- KMID: 2287559
- J Clin Neurol.
- 2013 Jul;9(3):196-197.
- doi: 10.3988/jcn.2013.9.3.196
No abstract available. -
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- Chronic Inflammatory Demyelinating Polyneuropathy Developed during Interferon-beta Therapy in a Patient with Multiple Sclerosis
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Lee CN, Kim BJ, Park KW, Koh SB, Kim HJ, Lee DH
- KMID: 2065613
- J Korean Neurol Assoc.
- 2006 Oct;24(5):486-490.
Preliminary studies have evaluated the effects of interferon beta formulations in the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP) because of pathogenic similarities between CIDP and multiple sclerosis (MS). However,... -
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- Calcium/Calmodulin-Dependent Protein Kinase is Involved in the Release of High Mobility Group Box 1 Via the Interferon-beta Signaling Pathway
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Ma L, Kim SJ, Oh KI
- KMID: 2424209
- Immune Netw.
- 2012 Aug;12(4):148-154.
Previously, we have reported that high mobility group box 1 (HMGB1), a proinflammatory mediator in sepsis, is released via the IFN-beta-mediated JAK/STAT pathway. However, detailed mechanisms are still unclear. In... -
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- Recombinant Interferon-Beta-1alpha Plus Ribavirin for the Treatment of Chronic HCV Infection: A Prospective, Randomized, Comparative Pilot Study
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Ahn SH, Lee HW, Kim YS, Kim JK, Han KH, Chon CY, Moon YM
- KMID: 1744235
- Gut Liver.
- 2009 Mar;3(1):20-25.
BACKGROUND/AIMS: Interferon beta (IFN-beta) has been shown to have antiviral activity, and thus could be useful in treating viral infections. Therefore, we compared the efficacy and safety of recombinant IFN-beta(IFN-beta-1a)... -
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- Antibodies to Interferon beta in Patients with Multiple Sclerosis Receiving CinnoVex, Rebif, and Betaferon
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Zare N, Zarkesh-Esfahani SH, Gharagozloo M, Shaygannejad V
- KMID: 1779423
- J Korean Med Sci.
- 2013 Dec;28(12):1801-1806.
- doi: 10.3346/jkms.2013.28.12.1801
Treatment with interferon beta (IFN-beta) induces the production of binding antibodies (BAbs) and neutralizing antibodies (NAbs) in patients with multiple sclerosis (MS). NAbs against IFN-beta are associated with a loss... -
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- Inhibitory Effect of IFN-beta, on the Antitumor Activity of Celecoxib in U87 Glioma Model
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Kim EK, Chung DS, Shin HJ, Hong YK
- KMID: 2190207
- J Korean Neurosurg Soc.
- 2009 Dec;46(6):552-557.
- doi: 10.3340/jkns.2009.46.6.552
OBJECTIVE: Interferon-beta, (IFN-beta) has been used in the treatment of cancers. Inhibition of the enzyme cyclooxygenase (COX) with celecoxib had a significantly suppressive effect on tumor growth, angiogenesis, and metastasis... -
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- Combination Therapy for Gliomas Using Temozolomide and Interferon-Beta Secreting Human Bone Marrow Derived Mesenchymal Stem Cells
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Park JH, Ryu CH, Kim MJ, Jeun SS
- KMID: 1881728
- J Korean Neurosurg Soc.
- 2015 May;57(5):323-328.
- doi: 10.3340/jkns.2015.57.5.323
OBJECTIVE: Malignant gliomas are the most common primary tumors of the central nervous system and the prognosis of patients with gliomas is poor. The combination of interferon-bata (IFN-beta) and temozolomide... -
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- Two Cases of Primary Sjogren's Syndrome Presenting as Relapsing-Remitting Multiple Sclerosis
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Cho JH, Kim SM, Kim JH, Chu CK, Lee MH, Shin HW, Doh WY, Sunwoo IN
- KMID: 2343096
- J Korean Neurol Assoc.
- 2004 Aug;22(4):410-413.
Sjogren's syndrome is a slowly progressive autoimmune disorder that predominantly affects major exocrine glands, and may also involve the central nervous system (CNS). It is sometimes very difficult to differentiate... -
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- An Analysis of Combined interferon-beta, BCNU and Radiation in the Treatment of Malignant Glioma
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Kye DK, Park YS, Cho KK, Lee KJ, Park SC, Choi CR
- KMID: 1955058
- J Korean Neurosurg Soc.
- 1995 Dec;24(12):1480-1485.
Prognosis for patients with a malignant glioma of the brain is, up to the present time, very poor. Surgery is unlikely to be curative and the primary goals of the... -
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- Role of Cyclic GMP-AMP Synthase in Sensing Human Immunodeficiency Virus
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Park YS, Kim IH, Koh YS
- KMID: 2168696
- J Bacteriol Virol.
- 2014 Jun;44(2):206-207.
- doi: 10.4167/jbv.2014.44.2.206
Cyclic guanosine monophosphate adenosine monophosphate (cGAMP) synthase (cGAS) detects human immunodeficiency virus (HIV) and produces cGAMP to induce cytokines. Reverse transcribed DNA of HIV is critical for triggering innate immune... -
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- Fluorescence Quenching Causes Systematic Dye Bias in Microarray Experiments Using Cyanine Dye
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Jeon H, Choi S
- KMID: 2166265
- Genomics Inform.
- 2007 Sep;5(3):113-117.
The development of microarray technology has facilitated the understanding of gene expression profiles. Despite its convenience, the cause of dye-bias that confounds data interpretation in dual-color DNA microarray experiments is... -
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- Study of Long Term Follow-up of Interferon Therapy in Chronic Viral Hepatitis: in 222 cases during 127 weeks
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Kim JI, Na JS, Bang CS, Park SH, Han JY, Suh JM, Kim JK, Lee YS, Chung KW, Sun HS
- KMID: 1531717
- Korean J Hepatol.
- 1997 Sep;3(3):241-251.
BACKGROUND/AIMS: To evaluate the therapeutic efficacy of interferon in chrcnic viral hepatitis, interferon was administered to 222 patients with biopsy proven chronic viral hepatitis. METHODS: 32 patients were excluded and the 190 patients was... -
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- Human Rhinovirus-induced Proinflammatory Cytokine and Interferon-beta Responses in Nasal Epithelial Cells From Chronic Rhinosinusitis Patients
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Kim JH, Kim YS, Cho GS, Kim NH, Gong CH, Lee BJ, Jang YJ
- KMID: 2147958
- Allergy Asthma Immunol Res.
- 2015 Sep;7(5):489-496.
- doi: 10.4168/aair.2015.7.5.489
PURPOSE: Asthma exacerbation from human rhinovirus (HRV) infection is associated with deficient antiviral interferon (IFN) secretion. Although chronic rhinosinusitis (CRS), an inflammatory upper airway disease, is closely linked to asthma,... -
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- Adenovirus Expressing Human Interferon Inhibits Replication of Foot and Mouth Disease Virus and Reduces Fatal Rate in Mice
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Chu JQ, Kim SM, Lee KN, Oem JK, Ko YJ, Lee HS, Kim YJ, Park JY, Kim KJ, Parida S, Oh Y, Paton DJ, Joo YS, Kim B, Park JH
- KMID: 1434751
- J Bacteriol Virol.
- 2012 Sep;42(3):224-231.
- doi: 10.4167/jbv.2012.42.3.224
Interferon is an important cytokine that plays a critical role in the initial host defense against viral infection. Recombinant human adenoviruses expressing human interferon-alpha (Ad-HIFNalpha) or pig interferon-beta fused with... -
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- Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling
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Krishnan J, Choi S
- KMID: 1806244
- Genomics Inform.
- 2012 Sep;10(3):153-166.
- doi: 10.5808/GI.2012.10.3.153
A variety of ligands differ in their capacity to bind the receptor, elicit gene expression, and modulate physiological responses. Such receptors include Toll-like receptors (TLRs), which recognize various patterns of... -
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- Long (27-nucleotides) small inhibitory RNAs targeting E6 protein eradicate effectively the cervical cancer cells harboring human papilloma virus
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Cho JS, Lee SW, Kim YM, Kim D, Kim DY, Kim YT
- KMID: 2148933
- Obstet Gynecol Sci.
- 2015 May;58(3):210-216.
- doi: 10.5468/ogs.2015.58.3.210
OBJECTIVE: This study was to identify small inhibitory RNAs (siRNAs) that are effective in inhibiting growth of cervical cancer cell lines harboring human papilloma virus (HPV) and to examine how... -
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- TRIF Deficiency does not Affect Severity of Ovalbumin-induced Airway Inflammation in Mice
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Kim TH, Kim DJ, Park JH, Park JH
- KMID: 2391721
- Immune Netw.
- 2014 Oct;14(5):249-254.
- doi: 10.4110/in.2014.14.5.249
Allergic asthma is a chronic pulmonary inflammatory disease characterized by reversible airway obstruction, hyperresponsiveness and eosinophils infiltration. Toll-like receptors (TLRs) signaling are closely associated with asthma and have emerged as... -
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