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Interleukin-32 in Inflammatory Autoimmune Diseases

Kim S

Interleukin-32 (IL-32) is a cytokine inducing crucial inflammatory cytokines such as tumor necrosis factor-alpha (TNFalpha) and IL-6 and its expression is elevated in various inflammatory autoimmune diseases, certain cancers, as...
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MicroRNA Regulation in Systemic Lupus Erythematosus Pathogenesis

Yan S, Yim LY, Lu L, Lau CS, Chan VS

MicroRNAs (miRNAs) are endogenous small RNA molecules best known for their function in post-transcriptional gene regulation. Immunologically, miRNA regulates the differentiation and function of immune cells and its malfunction contributes...
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Reduced Interleukin-17 and Transforming Growth Factor Beta Levels in Peripheral Blood as Indicators for Following the Course of Bladder Cancer

Baharlou R, Vasmehjani AA, Dehghani A, Ghobadifar MA, Khoubyari

Interleukin (IL) 17 is produced by T-helper (Th) 17 with a vigorous effect on cells of the immune system playing important roles in pathogenesis of immune-mediated diseases, including autoimmune disorders...
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Differential Roles of Lung Dendritic Cell Subsets Against Respiratory Virus Infection

Kim TH, Lee HK

Respiratory viruses can induce acute respiratory disease. Clinical symptoms and manifestations are dependent on interactions between the virus and host immune system. Dendritic cells (DCs), along with alveolar macrophages, constitute...
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Insulin Resistance and Serum Levels of Interleukin-17 and Interleukin-18 in Normal Pregnancy

Jahromi AS, Shojaei M, Ghobadifar MA

We performed this study to evaluate the role of Interleukin-17 (IL-17) and Interleukin-18 (IL-18) in insulin resistance during normal pregnancy. This descriptive cross sectional study was carried out on 97...
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Characterization of Two Novel mAbs Recognizing Different Epitopes on CD43

Kim S, Hong JW, Cho WD, Moon YR, Yoon SS, Kim MY, Hong KP, Lee YM, Yi JH, Ham YJ, Rah HC, Kim SR, Song HG

JL1, a specific epitope on CD43, is a potential biomarker for the diagnosis of acute leukemia. Although qualitative assays for detecting leukemia-specific CD43 exist, there is a need to develop...
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