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Chronic Spontaneous Urticaria: Pathogenesis and Treatment Considerations

Kaplan AP

The treatment of chronic spontaneous urticaria begins with antihistamines; however, the dose required typically exceeds that recommended for allergic rhinitis. Second-generation, relatively non-sedating H1-receptor blockers are typically employed up to...
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Potentially Inappropriate Medications by Beers Criteria in Older Outpatients: Prevalence and Risk Factors

Lim YJ, Kim HY, Choi J, Lee JS, Ahn AL, Oh EJ, Cho DY, Kweon HJ

BACKGROUND: Prescription of inappropriate medicine to elderly patients is a major public health care concern. The Beers criteria have been commonly employed as a screening tool to identify the use...
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Generalized Eosinophilic Pustular Folliculitis of Infancy Responding to Hydroxyzine

Lee JH, Kang JH, Cho BK, Park HJ

No abstract available.
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Considerations for submucosal midazolam administration in combination with oral and inhaled medications for sedation of pediatric dental patients

Baek K

  • KMID: 2310710
  • J Dent Anesth Pain Med.
  • 2015 Jun;15(2):47-52.
Sedation allows patients to maintain their airway independently and respond appropriately to physical stimulation and verbal command while maintaining a minimum depressed level of consciousness. Drugs commonly used for sedation...
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A retrospective study of deep sedation with concomitant administration of sedative agents in children undergoing surgical removal of a mesiodens

Lee SJ, Baek K

  • KMID: 2310744
  • J Dent Anesth Pain Med.
  • 2015 Dec;15(4):213-220.
BACKGROUND: Pediatric dentists face challenges when young patients require a mesiodens extraction. General anesthesia may be a burden to the child as well as the parent due to dental fears...
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A case of levocetirizine-induced fixed drug eruption and cross-reaction with piperazine derivatives

Kim MY, Jo EJ, Chang YS, Cho SH, Min KU, Kim SH

Fixed drug eruption is an uncommon adverse drug reaction caused by delayed cell-mediated hypersensitivity. Levocetirizine is an active (R)-enatiomer of cetirizine and there have been a few reports of fixed...
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Co-Administration of Subeffective Anxiolytic Doses of Diazepam and Hydroxyzine in Elevated Zero-Maze in Mice

Naghibi B, Rayatnia F

  • KMID: 2316050
  • Psychiatry Investig.
  • 2011 Jun;8(2):169-173.
OBJECTIVE: Benzodiazepines are from the most common drugs which are used for treatment of anxiety disorders. There are other drugs with antianxiety properties including antihistamines such as hydroxyzine, too. Body...
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A Case of Chlorpheniramine Maleate-Induced Hypersensitivity With Aspirin Intolerance

Kim MH, Lee SM, Lee SH, Kwon HS, Kim SH, Cho SH, Min KU, Kim YY, Chang YS

Antihistamines are commonly used to treat allergic disease, such as allergic rhinitis, urticaria, and angioedema. Although several previous reports describe hypersensitivity to antihistamines such as cetirizine and hydroxyzine, documented cases...
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A Case of Chronic Urticaria Presenting with Double Primary Malignancies in the Stomach and the Colon

  • KMID: 2299567
  • Korean J Asthma Allergy Clin Immunol.
  • 2009 Sep;29(3):208-211.
Chronic urticaria is a common disabling skin condition. Neoplasm has been case-reported as a comorbid disease with urticaria, although there is no reliable evidence suggesting a strong association between these...
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Two Cases of Urticaria Induced by Ebastine

  • KMID: 2299580
  • Korean J Asthma Allergy Clin Immunol.
  • 2009 Mar;29(1):64-68.
Ebastine (ebastel(R)) is one of the most frequently used antihistamines for allergic diseases. It is a long-acting H1 receptor antagonist belonging to the family of piperidines. Recently, we experienced 2...
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Sedative Effect of Sublingual Midazolam after Oral Chloral Hydrate or Hydroxyzine in Children

Lee H, Baek K, Jung S

Recently combining regimen of minimal doses of chloral hydrate, hydroxyzine and midazolam is good in sedation of children. Midazoalm, water soluble benzdiazepine, has rapid onset and relatively short duration of...
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The Comparison of Behavioral Response of Additional Submucosal Midazolam with Oral Chloral Hydrate, Hydroxyzine and Nitrous Oxide for Pediatric Conscious Sedation

Park H, Baek K, Jung S

No abstract available in English.
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Safety and Efficacy of Submucosal Midazolam When Combined with Oral Chloral Hydrate, Hydroxyzine and Nitrous Oxide Sedation by using Houpt's Scale

Park M, Kim Y, Jung S, Beak K

BACKGROUND: The purpose of this study was to compare the clinical safety and effect with and without additional submucosal midazolam to oral chloral hydrate and hydroxyzine when used for pediatric...
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Effect of Submucosal Midazolam on Percutaneous Saturation Percentage of Oxygen (SpOâ‚‚), End-tidal Carbon Dioxide (EtCOâ‚‚) and Physiologic Response When Combined with Chloral Hydrate, Hydroxyzine and Nitrous Oxide Sedation

Yu J, Kim Y, Jung S, Baek K

BACKGROUND: The aim of this study was to examine the difference of SpOâ‚‚, PR, EtCOâ‚‚, RR with submucosal injection of midazolam to oral chloral hydrate and hydroxyzine for pediatric patients METHODS:...
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The Sedative Effects of Submucosal Midazolam in Children

Lee YE, Park MK, Kim YH, Jung SH, Baek KW

PURPOSE: This retrospective study assessed the effectiveness of submucosal (SM) midazolam (M), oral chloral hydrate (CH), hydroxyzine (H), and nitrous oxide (N) 99 uncooperative pediatric dental patients over 182 sedation...
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Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense

Shin EH, Kim TH, Hong SJ, Park JH, Guk SM, Chai JY

The effects of anti-allergic drugs on intestinal mastocytosis and the expulsion of Neodiplostomum seoulense were observed in Sprague-Dawley rats, after oral infection with 500 metacercariae. The drugs used were hydroxyzine...
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Effects of Histamine and Hydroxyzine on the Bladder Contraction of Rat

Hong SK, Park EC, Oh SJ, Choi H

  • KMID: 1582910
  • Korean J Urol.
  • 2000 Mar;41(3):435-443.
No abstract available.
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A Case of Hydroxyzine Induced Torsades de Pointes

Kwon JW, Kang WC, Lee MH, Ahn SK, Kim SS

Torsades de pointes is a polymorphic ventricular tachycardia associated with prolonged QT interval and increased U wave amplitude. It has been found to be induced by various drugs, electrolyte imbalances,...
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A case of idiopathic anaphylaxis

Lee JK, Kim SH, Lim YJ, Park JK, Kim C, Cho YS, Yoo B, Moon HB

  • KMID: 1543171
  • Korean J Allergy.
  • 1997 Jun;17(2):192-197.
Idiopathic anaphylaxis is a life-threatening systemic reaction of unknown cause. The pathophysiology has not been established, although it has been postulated that the clinical manifestations of idiopathic anaphylaxis may result...
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The Therapeutic Effect of Anti - inflammatory Agents on the Lethal Effect of Toxemia Evoked by Vibrio vulnificus Cytolysin

Park JH, Park SD

  • KMID: 1891534
  • Korean J Dermatol.
  • 1996 Aug;34(4):561-571.
BACKGROUND: Many pathophysiological derangements associated with Vibrio vulnificus sepsis result from the release of toxins and enzymes into the circulation. Its effects are mediated via complex interaction of many endogenous...
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