Korean J Anesthesiol.  1987 Apr;20(2):152-158. 10.4097/kjae.1987.20.2.152.

Anesthesia for Thymectomy in Myasthenia Gravis - Report of 9 cases

• Sa HS
• Nam SH
• Bang SO
• Oh HK

• KMID: 1933312
• DOI: http://doi.org/10.4097/kjae.1987.20.2.152

Abstract

We have mnanaged the anesthetic and postoperative care in 9 patients with myasthenia gravis who underwent thymectomy and obtained following resultsa : 1) Premedication was glycoprrrolate 0.004mg/kg or atropine 0.01mg/kg and hydroxyzine 1~2mg/kg, I.M. Anesthetic induction was by thiopental 4~5mg/kg with 7he inhalation of halothane 1~2 % or enflurane 4~5%, and followed by endotracheal intubation. Anesthetic maintanance was done by N2O and halothane or enflurane. 2) Mean duration from the end of operation to intubation was 11.83+/-3.37hrs. 5 patients required reintubation. The mean duration from the extubation to reintubation was 33.11+/- 21.06hrs for these 5 patients. Over all this entire group of patients were placed on the respirator for a mean of 5.33+/-1.46dara. 3) Complication occured were 2 cases of cholinergic crisis, 1 cases of lung abscess, 2 cases of dyspnea and 1 case of tension pneumothorax 4) Abstinence of muscle relaxants, adequate respiratory care and the protection from cholinergic crisis were the most important factora for successful management.

MeSH Terms

Anesthesia*
Atropine
Dyspnea
Enflurane
Halothane
Humans
Hydroxyzine
Inhalation
Intubation
Intubation, Intratracheal
Lung Abscess
Myasthenia Gravis*
Pneumothorax
Postoperative Care
Premedication
Thiopental
Thymectomy*
Ventilators, Mechanical
Atropine
Enflurane
Halothane
Hydroxyzine
Thiopental