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Twenty-Nail Dystrophy Treated with Hydroxychloroquine in a Patient with Alopecia Areata

Bae SH, Jang SH, Won YH

No abstract available.
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Development and validation of LC-MS/MS for bioanalysis of hydroxychloroquine in human whole blood

Park JY, Song HH, Kwon YE, Kim SJ, Jang S, Joo SS

This study aimed to analyze a high-performance liquid chromatography (HPLC) separation using a pentafluorophenyl column of parent drug hydroxychloroquine (HCQ) and its active metabolite, desethylhydroxchloroquine (DHCQ) applying to determine bioequivalence...
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Peripapillary Retinal Nerve Fiber Layer Thicknesses Did Not Change in Long-term Hydroxychloroquine Users

Lee EJ, Kim SJ, Han JC, Eo DR, Lee MG, Ham DI, Kang SW, Kee C, Lee J, Cha HS, Koh EM

PURPOSE: To evaluate changes in the peripapillary retinal nerve fiber layer (RNFL) thicknesses using spectral-domain optical coherence tomography (SD-OCT) in hydroxychloroquine (HCQ) users. METHODS: The medical records of HCQ users were...
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Hydroxychloroquine Retinopathy Update

Ahn SJ, Lee BR

Hydroxychloroquine (HCQ) has been used widely for the treatment of several rheumatologic and dermatologic conditions, including systemic lupus erythematosus and rheumatoid arthritis. Its toxic effects on the retina, HCQ retinopathy,...
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A Case of Recurrent Steroid-dependent Kikuchi-Fujimoto Disease Successfully Treated with Hydroxychloroquine

Jang KM, Lee JM

Kikuchi-Fujimoto disease (KFD) is known as a self-limiting disease. The most common symptoms include fever, cervical lymphadenopathy, and pain, but nonspecific symptoms such as joint pain, nausea, chills, diaphoresis, and...
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Frequency and Clinical Characteristics of Hydroxychloroquine Retinopathy in Korean Patients with Rheumatologic Diseases

Eo DR, Lee MG, Ham DI, Kang SW, Lee J, Cha HS, Koh E, Kim SJ

This study aimed to evaluate the frequency and clinical characteristics of hydroxychloroquine (HCQ) retinopathy in Korean patients with rheumatologic diseases. We retrospectively reviewed medical records of 310 patients taking HCQ....
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Recurrent Kikuchi's Disease Treated by Hydroxychloroquine

Hyun M, So IT, Kim HA, Jung H, Ryu SY

Kikuchi-Fujimoto disease (KFD) is a benign, self-limiting disease, with a specific histopathology. It can be diagnosed clinically, and specific symptoms include fever and cervical lymphadenopathy. The histological finding of KFD...
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Hydroxychloroquine Retinopathy

Lee J, Lee JY

Hydroxychloroquine (HCQ) has been widely used for treatment of various rheumatic and dermatologic diseases. However, under a high cumulative dose, HCQ may cause retinal toxicity. In this review, we summarize...
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A Case of Recurrent Annular Erythema of Sjogren's Syndrome Treated with Hydroxychloroquine

Lee JH, Kim JH, Sung JY, Lee SH

  • KMID: 2246434
  • Korean J Dermatol.
  • 2014 Jan;52(1):64-66.
No abstract available.
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A Case of Subcutaneous Sarcoidosis Treated with Hydroxychloroquine

Na SY, Lee HY, Baek JO, Lee JR, Kim M, Roh JY

  • KMID: 2014479
  • Korean J Dermatol.
  • 2007 Dec;45(12):1315-1317.
A 54-year-old woman presented with a one-year history of multiple hard non-tender nodules on the trunk and both upper extremities without other accompanying systemic symptoms. Histopathologic findings of this subcutaneous...
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A Case of Rosai-Dorfman Disease Treated with Hydroxychloroquine

Baek JO, Lee HY, Lee JR, Kim M, Roh JY, Kim YC

  • KMID: 2302140
  • Korean J Dermatol.
  • 2007 Oct;45(10):1055-1059.
Rosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy (SMHL) is a benign histiocytic proliferative disorder of unknown etiology. It is accompanied by fever, leukocytosis, elevated erythrocyte sedimentation rate and polyclonal...
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Treatment of Generalized Granuloma Annulare with Low-dose Hydroxychloroquine

Kim CY, Park SY, Oh CW

  • KMID: 2248845
  • Korean J Dermatol.
  • 2007 Sep;45(9):969-972.
Generalized granuloma annulare (GGA) is benign granulomatous dermatosis of unknown causes characterized by a widespread papular eruption on the trunk and limbs. This differs from the localized form as it...
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A Case of Rhabdomyolysis in a Patient with Plasmidium vivax Malaria Treated with Hydroxychloroquine

Jung SJ, Kim YA, Ghil J, Ku NS, Kim JH, Park YS, Kim MS, Kim YK, Shin SY, Choi JY, Kim JM

  • KMID: 2170179
  • Infect Chemother.
  • 2006 Jun;38(3):174-178.
Rhabdomyolysis is a potentially life-threatening syndrome resulting form the breakdown of skeletal muscle fibers with leakage of muscle contents into the circulation. Rhabdomyolysis may complicate many disease states. In some...
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Effects of Hydroxychloroquine Co-administered with Chemotherapeutic Agents on Malignant Glioma Cell Lines: in vitro Study

Park YS, Choi JY, Chang JH, Park YG, Chang JW

  • KMID: 2067201
  • J Korean Neurosurg Soc.
  • 2005 Jul;38(1):47-53.
OBJECTIVE: Anti-malaria drugs may modulate tumor resistance to chemotherapeutic agents, but it has not been proven effective in the treatment of malignant gliomas. The aim of this study was to...
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Effect of Hydroxychloroquine on the Progression of Renal Injury in Chronic Uremic Rats

Yang JH, Choi YJ, Jin DC, Yang CW, Kim YS, Bang BK

  • KMID: 2079198
  • Korean J Nephrol.
  • 2001 Nov;20(6):964-974.
BACKGROUND: Hydroxychloroquine(HCQ) is known to inhibit proinflammatory cytokine production from stimulated mononuclear cells and to have anti-fibrotic effect. The aim of this study was to investigate if HCQ could ameliorate...
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Effects of Hydroxychloroquine on the Metabolism of Fas ligand of T cells

Min JK, Lee HJ, Lee WS, Park SH, Min SY, Cho ML, Cho CS, Kim HY

  • KMID: 2202458
  • J Korean Rheum Assoc.
  • 2000 Jun;7(2):127-139.
OBJECTIVE: Hydroxychloroquine (HCQ) is a drug that has been used to treat autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. However, the specific mechanism for its pharmacologic...
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Two Cases of Generalized Granuloma Annulare Controlled by Hydroxychloroquine

Park JH, Oh CK, Jang HS, Kwon KS, Chung TA

  • KMID: 2086198
  • Korean J Dermatol.
  • 1999 Feb;37(2):234-238.
We report the clinical evolution of two male patients with generalized granulama annulare(GGA) who were controlled with hydroxychloroquine. In the first case, a 3-year-old boy was treated with systemic steroid,...
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Open Clinical Trial of Methotrexate Alone and Combination of Methotrexate and Hydroxychloroquine in the Treatment of Rheumatoid Arthritis

Song CH, Park YB, Lee BK, Lee WK, Lee CW, Suh CH, Lee CH, Lee JS, Lee SK

  • KMID: 2306325
  • Korean J Med.
  • 1999 Jan;56(1):85-90.
OBJECTIVE: To assess the relative efficacy of combination therapy of methotrexate(MTX) and hydroxychloroquine(HCQ) in rheumatoid arthritis, we performed an open clinical trial for 6 months. METHODS: We compared the efficacy of combination...
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The Use of Hydroxychloroquine in Patients with Pemphigus Erythematosus

Kang SG, Lee CW

  • KMID: 2303531
  • Korean J Dermatol.
  • 1996 Dec;34(6):980-983.
Pemphigus erythematosus (PE) is a superficial type of pemphigus, which can be aggravated by sunlight (espicially UV light). Because of the known side effects of corticosteroids, we evaluated the efficacy...
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