Infect Chemother.
2006 Jun;38(3):174-178.
A Case of Rhabdomyolysis in a Patient with Plasmidium vivax Malaria Treated with Hydroxychloroquine
- Affiliations
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- 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. seran@yumc.yonsei.ac.kr
- 2AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Abstract
- Rhabdomyolysis is a potentially life-threatening syndrome resulting form the breakdown of skeletal muscle fibers with leakage of muscle contents into the circulation. Rhabdomyolysis may complicate many disease states. In some cases, patients with malaria may be complicated with rhabdomyolysis. Also hydroxychloroquine may induce myopathy and rhabdomyolysis. But there is no case report of rhabdomyolysis after use of hydroxychloroquine in a Korean patient with Plasmodium vivax malaria. Recently we experienced a patient who developed rhabdomyolysis 20 days after starting therapy with hydroxychloroquine for the treatment of P. vivax malaria. We report the case with the review of the literature.
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