Korean J Parasitol.  1998 Jun;36(2):143-146. 10.3347/kjp.1998.36.2.143.

A relapsed case of imported tertian malaria after a standard course of hydroxychloroquine and primaquine therapy

• Yi KJ
• Chung MH
• Kim HS
• Kim CS
• Pai SH

• KMID: 1715305
• DOI: http://doi.org/10.3347/kjp.1998.36.2.143

Abstract

Resistance of Plasmodium species to antimalarial agents has become increasingly challenging to the management and prevention of malaria. We experienced an imported case of tertian malaria due to Plasmodium vivax relapsed after a seemingly successful treatment with conventional course of hydroxychloroquine and primaquine. A 35-year-old man developed fever three days after return from India and mainland China. After his illness was diagnosed as tertian malaria, he was managed with hydroxychloroquine and then primaquine (primaquine base 15 mg/day for 14 days). Thereafter peripheral blood smears showed no malarial parasites, and there was no relapse of symptom until the 55th post-treatment day, however, six months after the above treatment tertian malaria relapsed. He was managed with the same medications again and malaria did not relapse for 10 months.

MeSH Terms

Adult
Animal
Antimalarials/therapeutic use*
Case Report
Human
Hydroxychloroquine/therapeutic use*
Malaria, Vivax/drug therapy*
Male
Primaquine/therapeutic use*
Recurrence
Time Factors
Travel