- Optimization of Extraction Condition of Hesperidin in Citrus unshiu Peels using Response Surface Methodology
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Lee J, Park S, Jeong JY, Jo YH, Lee MK
- KMID: 2312886
- Nat Prod Sci.
- 2015 Jun;21(2):141-145.
- doi: 10.0000/nps.2015.21.2.141
Hesperidin, which is the most abundant flavonoid of Citrus unshiu (Rutaceae), has been reported to possess diverse activities and widely used as functional foods and cosmetics. For the development of... -
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- Maximization of Extracted Condition of Pro-angiogenic Components in Citrus unshiu Peels using Dimethyl Sulfoxide
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Lee J, Kim M, Kim JH
- KMID: 2366698
- Nat Prod Sci.
- 2016 Dec;22(4):287-292.
- doi: 10.20307/nps.2016.22.4.287
Aqueous extraction of Citrus unshiu peels (AECUP) is mainly comprised with pro-angiogenichesperidin and narirutin. In this study, we report approaches to increasing the yields of extracted hesperidin and narirutinfrom Citrus... -
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- Hesperetin Stimulates Cholecystokinin Secretion in Enteroendocrine STC-1 Cells
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Kim HY, Park M, Kim K, Lee YM, Rhyu MR
- KMID: 1502513
- Biomol Ther.
- 2013 Mar;21(2):121-125.
Hesperetin (3',5,7-trihydroxy 4'-methoxyflavanone) and its glycoside hesperidin (hesperetin 7-rhamnoglucoside) in oranges have been reported to possess pharmacological effects related to anti-obesity. However, hesperetin and hesperidin have not been studied on... -
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- Hesperidin Suppresses Melanosome Transport by Blocking the Interaction of Rab27A-Melanophilin
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Kim B, Lee JY, Lee HY, Nam KY, Park J, Lee SM, Kim JE, Lee JD, Hwang JS
- KMID: 2048304
- Biomol Ther.
- 2013 Sep;21(5):343-348.
We investigated the inhibitory effects of hesperidin on melanogenesis. To find melanosome transport inhibitor from natural products, we collected the structural information of natural products from Korea Food and Drug... -
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- Hesperidin Attenuates Ultraviolet B-Induced Apoptosis by Mitigating Oxidative Stress in Human Keratinocytes
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Hewage SR, Piao MJ, Kang KA, Ryu YS, Han X, Oh MC, Jung U, Kim IG, Hyun JW
- KMID: 2164224
- Biomol Ther.
- 2016 May;24(3):312-319.
- doi: 10.4062/biomolther.2015.139
Human skin cells undergo pathophysiological processes via generation of reactive oxygen species (ROS) upon excessive exposure to ultraviolet B (UVB) radiation. This study investigated the ability of hesperidin (C28H34O15) to... -
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- Benefits of hesperidin in central nervous system disorders: a review
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Kim J, Wie MB, Ahn M, Tanaka A, Matsuda H, Shin T
- KMID: 2466688
- Anat Cell Biol.
- 2019 Dec;52(4):369-377.
- doi: 10.5115/acb.19.119
Citrus species contain significant amounts of flavonoids that possess antioxidant activities; furthermore, dietary citrus is not associated with adverse effects or cytotoxicity in healthy individuals. Hesperidin, which is an abundant... -
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- Clinical Effects of Venitol(R) on Complications after Hemorrhoidectomy Prospective Randomized and Placebo-controlled Trial
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Lee HW, Lee WY, Chun HK
- KMID: 1835115
- J Korean Soc Coloproctol.
- 1998 Dec;14(4):761-766.
Fifty four patients who received closed hemorrhoidectomy were randomized into two parallel groups and treated with Venitol(R)(a micronized flavonoidic fraction containing diosmin 450 mg and hesperidin 50 mg) (group 1)... -
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- Inhibitory Effects of Yuzu and Its Components on Human Platelet Aggregation
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Kim TH, Kim HM, Park SW, Jung YS
- KMID: 2380348
- Biomol Ther.
- 2015 Mar;23(2):149-155.
- doi: 10.4062/biomolther.2015.011
Our previous study demonstrated that yuzu has an anti-platelet effect in rat blood. In the present study, we examined whether the anti-platelet effect of yuzu can be extended to human... -
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- Composition of Flavonoids and Antioxidative Activity from Juice of Jeju Native Citrus Fruits during Maturation
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Kim YD, Ko WJ, Koh KS, Jeon YJ, Kim SH
- KMID: 2264727
- Korean J Nutr.
- 2009 Apr;42(3):278-290.
- doi: 10.4163/kjn.2009.42.3.278
This study aims to evaluate the changes of flavonoid contents and antioxidants activity of Jeju native citrus fruits juice according to the harvest date. Flavonoids such as quercatagetin, narirutin, hesperidin... -
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- The relaxing effect of Poncirus fructus and its flavonoid content on porcine coronary artery
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Yu DJ, Jun JH, Kim TJ, Suh DK, Youn DH, Kim TW
- KMID: 1787649
- Lab Anim Res.
- 2015 Mar;31(1):33-39.
- doi: 10.5625/lar.2015.31.1.33
Coronary artery disease is a common occurrence in human, and causes enormous social cost. Poncirus fructus (PF), the dried immature fruits of Poncirus trifoliata Rafinesquem, is used in the treatment... -
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- Pull-out bond strength of a self-adhesive resin cement to NaOCl-treated root dentin: effect of antioxidizing agents
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Khoroushi , Kachuei M
- KMID: 2316878
- Restor Dent Endod.
- 2014 May;39(2):95-103.
OBJECTIVES: This study evaluated the effect of three antioxidizing agents on pull-out bond strengths of dentin treated with sodium hypochlorite. MATERIALS AND METHODS: Root canals of 75 single-rooted human teeth were... -
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- Effect of antioxidants on push-out bond strength of hydrogen peroxide treated glass fiber posts bonded with two types of resin cement
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Khoroushi , Mazaheri H, Tarighi P, Samimi P, Khalighinejad N
- KMID: 2316912
- Restor Dent Endod.
- 2014 Nov;39(4):303-309.
- doi: 10.5395/rde.2014.39.4.303
OBJECTIVES: Hydrogen peroxide (H2O2) surface treatment of fiber posts has been reported to increase bond strength of fiber posts to resin cements. However, residual oxygen radicals might jeopardize the bonding... -
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- Antioxidant Activities and Tyrosinase Inhibitory Effects of Different Extracts from Pleurotus ostreatus Fruiting Bodies
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Alam N, Yoon KN, Lee KR, Shin PG, Cheong JC, Yoo YB, Shim JM, Lee MW, Lee UY, Lee TS
- KMID: 2312593
- Mycobiology.
- 2010 Dec;38(4):295-301.
We evaluated the antioxidant activity and tyrosinase inhibitory effects of Pleurotus ostreatus fruiting bodies extracted with acetone, methanol, and hot water. The antioxidant activities were tested against beta-carotene-linoleic acid, reducing... -
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- Assessment of Antioxidant and Phenolic Compound Concentrations as well as Xanthine Oxidase and Tyrosinase Inhibitory Properties of Different Extracts of Pleurotus citrinopileatus Fruiting Bodies
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Alam N, Yoon KN, Lee KR, Kim HY, Shin PG, Cheong JC, Yoo YB, Shim MJ, Lee MW, Lee TS
- KMID: 2312605
- Mycobiology.
- 2011 Mar;39(1):12-19.
Cellular damage caused by reactive oxygen species has been implicated in several diseases, thus establishing a significant role for antioxidants in maintaining human health. Acetone, methanol, and hot water extracts... -
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