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Cancer Stem Cells: Biological Features and Targeted Therapeutics

Song SY, Seo D

Advance in stem cells (SCs) has become significant by the isolation of the tissue-specific SCs in a tissue, because it is the beginning of using SC utility for regenerative medicine....
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Current Concepts in Stem Cell Therapy for Cardiovascular Diseases: What We Know and Don't Know

Jeon KH

Medical therapies and mechanical interventions for the treatment of myocardial infarction (MI) and ischemic heart failure have seen great progress. However, current therapies only slow the progression to heart failure,...
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Adult Stem Cell Therapy in Chronic Liver Diseases

Eom YW, Baik SK

The transplantation of mesenchymal stem cells (MSCs) represents a potentially effective therapy for chronic liver diseases. The potential of MSCs in the treatment of chronic liver disease is based on...
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Stem Cell Therapy for Neurodegenerative Diseases

Yee JZ, Oh KW, Kim SH

Neurodegenerative diseases are the hereditary and sporadic conditions which are characterized by progressive neuronal degeneration. Neurodegenerative diseases are emerging as the leading cause of death, disabilities, and a socioeconomic burden...
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Recent Advances in Skeletal Muscle Stem Cells for Duchenne Muscular Dystrophy Treatment

Yang JY, Jeong J

Muscle stem cells, which are known as satellite cells have heterogeneous components of committed myogenic progenitors, non-committed satellite cells, and mesenchymal stem cells. This distinguishing organization of self-renewal and differentiation...
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The Current Status of Directed Differentiation Technology

Lee SE, Choi D

The direct reprogramming of a terminally differentiated cell into another lineage using defined combinations of factors has fundamentally changed traditional concepts of the inalterability of differentiated cells. Many studies have...
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Advanced Research on Stem Cell Therapy for Hepatic Diseases: Potential Implications of a Placenta-derived Mesenchymal Stem Cell-based Strategy

Kim GJ

The category of chronic liver diseases comprise one of the most common medical diagnoses worldwide. Currently, orthotopic liver transplantation is the only effective treatment for end-stage hepatic disease, but this...
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Recent Advances for Enhancing Drug Metabolizing Functions of Hepatocyte-like Cells Derived from Human Pluripotent Stem Cells

Han J, Kim JH

Hepatocyte-like cells (HLCs) derived from human pluripotent stem cells are a promising cell source for drug screening and toxicity tests. Thus, various hepatic differentiating protocols have been developed, leading to...
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Induced Pluripotent Stem Cells: Next Generation Stem Cells to Clinical Applications

Cha J, Park S, Lee SB

Induced pluripotent stem cells (iPSC) are specially manipulated cells from somatic cells by the introduction of four factors that are reprogrammed. The properties of iPSC are similar to embryonic stem...
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New Horizons in Stem Cell Research

Choi D

No abstract available.
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