- Change of mechanical properties in Nitinol by fatigue load
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Ha KB, Shon WS
- KMID: 2271363
- Korean J Orthod.
- 1993 Dec;23(4):725-734.
Nitinol wires are now widely used in the orthodontic field because of their unique shape memory effect and superelasticity. But sometimes Nitinol wires are deformed in clinical use. Fatigue load... -
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- Effects of estrogen and progesterone on the proliferation and activity of osteoblastic cells
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Ha KB, Son WS, Kim SW
- KMID: 2271880
- Korean J Orthod.
- 2001 Apr;31(2):237-248.
Biomechanical reactions of tooth movement are the combination of bone formation and resorption, in which many paracrine factors are involved. The sex hormone is one of the paracrine factors and... -
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- DA-6034 ameliorates hepatic steatosis and inflammation in high fat diet-induced obese mice
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Kim HM, Kwon MH, Lee ES, Ha KB, Chung CH
- KMID: 2554771
- J Yeungnam Med Sci.
- 2024 Apr;41(2):103-112.
- doi: 10.12701/jyms.2023.01389
Background: Nonalcoholic fatty liver disease (NAFLD) is characterized by an increase in hepatic triglyceride content and increased inflammatory macrophage infiltration through the C-C motif chemokine receptor (CCR) 5 pathway in... -
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- Umbelliferone Ameliorates Hepatic Steatosis and Lipid-Induced ER Stress in High-Fat Diet-Induced Obese Mice
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Park NW, Lee ES, Ha KB, Jo SH, Kim HM, Kwon MH, Chung CH
- KMID: 2541126
- Yonsei Med J.
- 2023 Apr;64(4):243-250.
- doi: 10.3349/ymj.2022.0354
Purpose: Among the characteristics of non-alcoholic fatty liver disease (NAFLD), hepatic steatosis is due to excessive fat accumulation and causes liver damage and lipotoxicity, which are associated with insulin resistance,... -
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- Beneficial Effects of a Curcumin Derivative and Transforming Growth Factor-β Receptor I Inhibitor Combination on Nonalcoholic Steatohepatitis
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Ha KB, Lee ES, Park NW, Jo SH, Shim S, Kim DK, Ahn CM, Chung CH
- KMID: 2544729
- Diabetes Metab J.
- 2023 Jul;47(4):500-513.
- doi: 10.4093/dmj.2022.0110
Background: Curcumin 2005-8 (Cur5-8), a derivative of curcumin, improves fatty liver disease via AMP-activated protein kinase activation and autophagy regulation. EW-7197 (vactosertib) is a small molecule inhibitor of transforming growth... -
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- EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation
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Ha KB, Sangartit W, Jeong AR, Lee ES, Kim HM, Shim S, Kukongviriyapan U, Kim DK, Lee EY, Chung CH
- KMID: 2527141
- Endocrinol Metab.
- 2022 Feb;37(1):96-111.
- doi: 10.3803/EnM.2021.1305
Background: Diabetic nephropathy (DN) is characterized by albuminuria and accumulation of extracellular matrix (ECM) in kidney. Transforming growth factor-β (TGF-β) plays a central role in promoting ECM accumulation. We aimed... -
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- Tetrahydrocurcumin Ameliorates Kidney Injury and High Systolic Blood Pressure in High-Fat Diet-Induced Type 2 Diabetic Mice
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Sangartit W, Ha KB, Lee ES, Kim HM, Kukongviriyapan U, Lee EY, Chung CH
- KMID: 2519669
- Endocrinol Metab.
- 2021 Aug;36(4):810-822.
- doi: 10.3803/EnM.2021.988
Background: Activation of the intrarenal renin-angiotensin system (RAS) is implicated in the pathogenesis of kidney injury and hypertension. We aimed to investigate the protective effect of tetrahydrocurcumin (THU) on intrarenal... -
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- DWN12088, A Prolyl-tRNA Synthetase Inhibitor, Alleviates Hepatic Injury in Nonalcoholic Steatohepatitis
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Lee DK, Jo SH, Lee ES, Ha KB, Park NW, Kong DH, Park SI, Park JS, Chung CH
- KMID: 2551266
- Diabetes Metab J.
- 2024 Jan;48(1):97-111.
- doi: 10.4093/dmj.2022.0367
Background: Nonalcoholic steatohepatitis (NASH) is a liver disease caused by obesity that leads to hepatic lipoapoptosis, resulting in fibrosis and cirrhosis. However, the mechanism underlying NASH is largely unknown, and... -
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