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Phylogenetic Status of an Unrecorded Species of Curvularia, C. spicifera, Based on Current Classification System of Curvularia and Bipolaris Group Using Multi Loci

Jeon SJ, Nguyen TT, Lee HB

A seed-borne fungus, Curvularia sp. EML-KWD01, was isolated from an indigenous wheat seed by standard blotter method. This fungus was characterized based on the morphological characteristics and molecular phylogenetic analysis....
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Glucose Oxidation and Production of Reactive Oxygen Species (ROS) in INS-1 Cells and Rat Islet Cells Exposed to High Glucose

Yoon JS, Won KC, Lee HW

BACKGROUND: Chronic exposure of pancreatic islets to supraphysiologic concentrations of glucose causes beta cell dysfunction that is a process known as glucose toxicity. It has been reported that hyperglycemia increases...
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Antioxidative and aldose reductase-inhibitory effects of a fermentation filtrate of Rubus coreanus

Kwon SC, Kim YB

Antioxidative and aldose reductase (AR)-inhibitory effects of a fermentation filtrate of Rubus coreanus (FRC) were investigated using corneal/retinal homogenate and lens cytosol, respectively. Rat corneal/retinal homogenate was treated with 50...
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Comparison of the Effectiveness in the Application of Competitive and Noncompetitive Internal Control for the Laboratory Developed Polymerase Chain Reaction

Shin S, Kang JW, Kang JW, Seo YI, Min H

BACKGROUND: A nucleic acid amplification test was adopted to detect transfusion-transmitted infectious agents. In the case of HTLV, however, there was no internal control (IC) because the laboratory developed polymerase...
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Reduced dihydroxyacetone sensitivity and normal sensitivity to glyceraldehyde and oxidizing agent of ATP-sensitive K+ channels of pancreatic beta cells in NIDDM rats

Song DK, Park WK, Bae JH, Park MK, Kim SJ, Ho WK, Earm YE

The inhibition of ATP-sensitive K+(KATP) channels in pancreatic beta cells is a key step of insulin secretion induced by glucose. Glucose-induced insulin secretion from the beta cells is selectively...
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Acetyl Eburicoic Acid from Laetiporus sulphureus var. miniatus Suppresses Inflammation in Murine Macrophage RAW 264.7 Cells

Saba E, Son Y, Jeon BR, Kim SE, Lee IK, Yun BS, Rhee MH

The basidiomycete Laetiporus sulphureus var. miniatus belongs to the Aphyllophorales, Polyporaceae, and grows on the needleleaf tree. The fruiting bodies of Laetiporus species are known to produce N-methylated tyramine derivatives,...
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Effects of Fixation and Storage of Human Tissue Samples on Nucleic Acid Preservation

Nam SK, Im J, Kwak Y, Han N, Nam KH, Seo AN, Lee HS

  • KMID: 1875756
  • Korean J Pathol.
  • 2014 Feb;48(1):36-42.
BACKGROUND: Because of recent advances in the molecular diagnosis of cancer patients, tissue quality has become more important in daily practice. METHODS: To evaluate the effects of fixative, duration of fixation,...
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Metabolism of Reactive Oxygen Species in Neutrophils from Patients with End-Stage Renal Disease

Choi HJ, Kwon JK, Mun KC, Chang EJ, Kwak CS, Han SY, Hwang EA, Park SB, Kim HC

  • KMID: 2079400
  • Korean J Nephrol.
  • 2004 May;23(3):429-438.
BACKGROUND: The present study was aimed to know the cause of impaired bactericidal activity, especially the metabolism of oxygen free radicals in neutrophils from patients with end-stage renal disease (ESRD)....
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The Developmental Differences of Damage in Rat Brain by Systemic Kainic Acid Injection

Kim CM, Em CS, Jeon YH, Son YH, Kim H

  • KMID: 2224619
  • Korean J Anat.
  • 1997 Aug;30(4):397-410.
Kainic acid[KA], a glutamic acid analogue, has been widely used as a excitotoxin in the study of neurotoxicity due to its ability to induce strong excitation and to increase intracellular...
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Effect of Ginkgo Biloba Extract on N-Methyl-D-Aspartic Acid Receptor Subunit 2B Expression in a Salicylate-Induced Ototoxicity Model

Lee SY, Han SY, Shim YJ, Han JJ, Cho D, Kim JE, Kim YH

OBJECTIVES.: Sodium salicylate (SS) is well known for its ototoxic properties that induce functional and morphological changes in the cochlea and brain. Ginkgo biloba extract (GBE) has been widely used...
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Effects of 1,25-dihydroxyvitamin D₃ on the differentiation of MC3T3-E1 osteoblast-like cells

Kim HS, Zheng M, Kim DK, Lee WP, Yu SJ, Kim BO

PURPOSE: The purpose of this study was to evaluate the effects of 1,25-dihydroxyvitamin D₃ on the proliferation, differentiation, and matrix mineralization of MC3T3-E1 osteoblast-like cells in vitro. METHODS: MC3T3-E1 osteoblastic cells...
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Molecular genetic characterization of alternatively spliced CD44 transcripts in human stomach carcinoma

Kim YS, Chi SG, Kim YW, Park YK, Yoon C

CD44 is a member of cell surface glycoproteins which are involved in cell-matrix adhesion and tumor metastasis. Certain types of tumors express complex CD44 isoforms generated by alternative splicing...
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Enhanced tyrosine hydroxylase expression in PC12 cells co-cultured with feline mesenchymal stem cells

Jin GZ, Yin XJ, Yu XF, Cho SJ, Lee HS, Lee HJ, Kong IK

Mesenchymal stem cells (MSCs) secrete a variety of neuroregulatory molecules, such as nerve growth factor, brain-derived neurotrophic factor, and glial cell-derived neurotrophic factor, which upregulate tyrosine hydroxylase (TH) gene expression...
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