- Glucose Metabolism in the Intestine
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Ha E
- KMID: 2328898
- J Metab Bariatr Surg.
- 2016 Jun;5(1):1-3.
- doi: 10.0000/jmbs.2016.5.1.1
Few are familiar with the gluconeogenesis that occurs in the intestine under fasting or the influence of insulin. Recently, however, studies that revealed the function of intestinal gluconeogenesis as a... -
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- Alterations of epinephrine-induced gluconeogenesis in aging
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Kim K, Cho SC, Cova A, Jang IS, Park SC
- KMID: 1123807
- Exp Mol Med.
- 2009 May;41(5):334-340.
- doi: 10.3858/emm.2009.41.5.037
The effects of glucagon and epinephrine on gluconeogenesis in young (4 month) and old (24 month) Fisher 344 rat hepatocytes were compared. In contrast to glucagon, which had a similar... -
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- AMPK Activator AICAR Inhibits Hepatic Gluconeogenesis and Fatty Acid Oxidation
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Kim JY, Koh EH, Lee WJ, Han SM, Youn JY, Park HS, Kim HS, Kim MS, Park JY, Lee KU
- KMID: 2177799
- J Korean Diabetes Assoc.
- 2005 Jan;29(1):6-14.
BACKGROUND: Recent studies have demonstrated that adiponectin and metformin activate AMPK in the liver, and adiponectin and metformin stimulate fatty acid oxidation while inhibiting glucose production in liver. These results... -
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- Roles of Protein Arginine Methyltransferases in the Control of Glucose Metabolism
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Han HS, Choi D, Choi S, Koo SH
- KMID: 2384238
- Endocrinol Metab.
- 2014 Dec;29(4):435-440.
- doi: 10.3803/EnM.2014.29.4.435
Glucose homeostasis is tightly controlled by the regulation of glucose production in the liver and glucose uptake into peripheral tissues, such as skeletal muscle and adipose tissue. Under prolonged fasting,... -
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- The Role of the Kidney in Glucose Metabolism
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Rhee SY
- KMID: 2173884
- J Korean Diabetes.
- 2014 Sep;15(3):142-145.
- doi: 10.4093/jkd.2014.15.3.142
It is well known that the kidney is important for maintaining glucose homeostasis in vivo. However, the physiological role of the kidney in glucose metabolism is typically underestimated. Recently, a... -
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- Adiponectin and thiazolidinedione targets CRTC2 to regulate hepatic gluconeogenesis
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Yoon YS, Ryu D, Lee MW, Hong S, Koo SH
- KMID: 1119323
- Exp Mol Med.
- 2009 Aug;41(8):577-583.
- doi: 10.3858/emm.2009.41.8.063
During fasting periods, hepatic glucose production is enhanced by glucagon to provide fuels for other organs. This process is mediated via cAMP-dependent induction of the CREB regulated transcriptional coactivator (CRTC)... -
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- Insulin Resistance and Intracellular Thyroid Hormone Dysfunction
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Kim EY
- KMID: 2322004
- J Korean Soc Pediatr Endocrinol.
- 2009 Dec;14(2):94-99.
Insulin resistance and diabetes combine to impair mitochondrial oxidative metabolism and cause lipid accumulation in non-adipose tissues such as skeletal muscles and the liver. The thyroid hormone stimulates thermogenesis, mitochondrial... -
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- Regulation of glucose metabolism from a liver-centric perspective
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Han HS, Kang G, Kim JS, Choi BH, Koo SH
- KMID: 2361505
- Exp Mol Med.
- 2016 Mar;48(3):e218.
- doi: 10.1038/emm.2015.122
Glucose homeostasis is tightly regulated to meet the energy requirements of the vital organs and maintain an individual's health. The liver has a major role in the control of glucose... -
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- Gynura procumbens extract improves insulin sensitivity and suppresses hepatic gluconeogenesis in C57BL/KsJ-db/db mice
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Choi SI, Lee HA, Han JS
- KMID: 2434085
- Nutr Res Pract.
- 2016 Oct;10(5):507-515.
- doi: 10.4162/nrp.2016.10.5.507
BACKGROUND/OBJECTIVES: This study was designed to investigate whether Gynura procumbens extract (GPE) can improve insulin sensitivity and suppress hepatic glucose production in an animal model of type 2 diabetes. MATERIALS/METHODS: C57BL/Ksj-db/db... -
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- Sick Day Management in Patients with Diabetes
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Lee HJ
- KMID: 1436187
- J Korean Diabetes.
- 2012 Mar;13(1):44-47.
- doi: 10.4093/jkd.2012.13.1.44
People whose diabetes is under good metabolic control should not experience more illness or infection than people without diabetes. However, when any illness occurs in someone with diabetes, the potential... -
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- Blood Sugar Control in Alcohol-Consuming Diabetics
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Cho DH
- KMID: 2059866
- J Korean Diabetes.
- 2012 Jun;13(2):91-94.
- doi: 10.4093/jkd.2012.13.2.91
Alcohol influences glucose metabolism in both diabetic and non-diabetic individuals. Moderate alcohol consumption significantly decreases fasting glucose levels, but does not affect postprandial glucose levels. However, acute alcohol intake without... -
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- Glycemic Management of Patients Undergoing Dialysis
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Kim MK
- KMID: 2354280
- J Korean Diabetes.
- 2016 Sep;17(3):164-167.
- doi: 10.4093/jkd.2016.17.3.164
Diabetes mellitus is the leading cause of end-stage renal disease in Korea. The management of glycemic control in patients undergoing dialysis is challenging due to the complexity of the treatment... -
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- Role of Pyruvate Dehydrogenase Kinase 4 in Regulation of Blood Glucose Levels
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Jeoung NH, Harris RA
- KMID: 2029884
- Korean Diabetes J.
- 2010 Oct;34(5):274-283.
- doi: 10.4093/kdj.2010.34.5.274
In the well-fed state a relatively high activity of the pyruvate dehydrogenase complex (PDC) reduces blood glucose levels by directing the carbon of pyruvate into the citric acid cycle. In... -
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- Glucose Homeostasis during Fetal and Neonatal Period
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Cho WI, Chung HR
- KMID: 2316286
- Korean J Perinatol.
- 2016 Jun;27(2):95-102.
- doi: 10.14734/kjp.2016.27.2.95
Glucose is essential for energy metabolism in human, especially in brain, and is a source of energy storage in the form of glycogen, fat and protein. During fetal life, the... -
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- Sirt1 as a New Therapeutic Target in Metabolic and Age-Related Diseases
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Lee DH
- KMID: 1730001
- Chonnam Med J.
- 2010 Aug;46(2):67-73.
- doi: 10.4068/cmj.2010.46.2.67
Sirt1 among the mammalian sirtuins has generated intense scientific interest in recent years, mainly because of its effects on longevity, metabolism, and other aging-related processes. Via nicotinamide adenine dinucleotide (NAD)-dependent... -
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- The Impacts of Alcohol Consumption on Glucose Metabolism
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Jang JE, Koh EH
- KMID: 2059864
- J Korean Diabetes.
- 2012 Jun;13(2):81-84.
- doi: 10.4093/jkd.2012.13.2.81
The relationship between alcohol consumption and carbohydrate metabolism is complex and is not fully understood. Alcohol not only increases oxidative stress during metabolism, but also inhibits both gluconeogenesis and glycogenolysis... -
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- Sleep-Disordered Breathing and Metabolic Dysfunction
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Joo S, Shin C
- KMID: 2317417
- Sleep Med Psychophysiol.
- 2005 Jun;12(1):17-22.
Sleep-disordered breathing (SDB) is associated with increased cardiovascular and cerebrovascular morbidity. Epidemiological and clinic-based studies have shown that SDB is related to impaired glucose tolerance and increased insulin resistance, independent... -
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- Effects of Caloric Restriction on the Expression of PGC-1 and PPARs mRNA in Liver of Otsuka Long-Evans Tokushima Fatty Rats
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Kim SY, Kim JH, Bae HY, Lee BR
- KMID: 2177607
- J Korean Diabetes Assoc.
- 2006 May;30(3):161-169.
- doi: 10.4093/jkda.2006.30.3.161
BACKGROUND: Gluconeogenesis is strongly stimulated during fasting and is aberrantly activated in diabetes mellitus. PPARgamma-coactivator 1 (PGC-1) and Peroxisome proliferator -activated receptors (PPARs) costimulate the expression of key enzymes of... -
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- A Journey to Understand Glucose Homeostasis: Starting from Rat Glucose Transporter Type 2 Promoter Cloning to Hyperglycemia
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Ahn YH
- KMID: 2449622
- Diabetes Metab J.
- 2018 Dec;42(6):465-471.
- doi: 10.4093/dmj.2018.0116
My professional journey to understand the glucose homeostasis began in the 1990s, starting from cloning of the promoter region of glucose transporter type 2 (GLUT2) gene that led us to... -
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- Hyperinsulinemic Hypoglycemia Caused by Acute Reduction of Renal Function on an Eldery Patient Without Diabetes
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Yeo JH, Kim JE, Park ES, Park JH, Kim DS, Choi WH, Ahn YH, Kim HJ, Hong SM, Lee CB
- KMID: 1817325
- J Korean Geriatr Soc.
- 2015 Mar;19(1):34-39.
- doi: 10.4235/jkgs.2015.19.1.34
In patient with renal failure, hypoglycemia may develop because of decreased caloric intake, diminished renal insulin degradation and clearance, reduced renal gluconeogenesis and hepatic glucose production, impaired release of counter-regulatory... -
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