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Curcumin attenuates the middle cerebral artery occlusion-induced reduction in gamma-enolase expression in an animal model

Gim SA, Lee SR, Shah FA, Koh PO

Curcumin exerts a protective effect in cerebral ischemia through its anti-oxidant and anti-inflammatory activities. gamma-enolase is a glycolytic enzyme expressed in neurons that is known to exerts a neuroprotective effect....
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Focal cerebral ischemic injury decreases calbindin expression in brain tissue and HT22 cells

Ouh IO, Kim YM, Gim SA, Koh PO

  • KMID: 2312108
  • Lab Anim Res.
  • 2013 Sep;29(3):156-161.
Calbindin is a calcium binding protein that controls intracellular calcium levels and has a neuroprotective function against apoptotic stimuli. We investigated the expression of calbindin in ischemic brain injury. Focal...
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Ferulic acid prevents the injury-induced decrease of gamma-enolase expression in brain tissue and HT22 cells

Gim SA, Koh PO

  • KMID: 2312114
  • Lab Anim Res.
  • 2014 Mar;30(1):8-13.
Ferulic acid is known to act as a protective agent in cerebral ischemia through its anti-oxidant activity. gamma-Enolase is a neuron-specific enolase that also exerts a neuroprotective effect. Here, we...
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Curcumin treatment recovery the decrease of protein phosphatase 2A subunit B induced by focal cerebral ischemia in Sprague-Dawley rats

Shah FA, Park DJ, Gim SA, Koh PO

Curcumin provides various biological effects through its anti-inflammatory and antioxidant properties. Moreover, curcumin exerts a neuroprotective effect against ischemic condition-induced brain damage. Protein phosphatase 2A (PP2A) is a ubiquitous serine...
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Ferulic acid regulates the AKT/GSK-3beta/CRMP-2 signaling pathway in a middle cerebral artery occlusion animal model

Gim SA, Sung JH, Shah FA, Kim MO, Koh PO

Ferulic acid, a component of the plants Angelica sinensis (Oliv.) Diels and Ligusticum chuanxiong Hort, exerts a neuroprotective effect by regulating various signaling pathways. This study showed that ferulic acid...
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Ginkgo biloba extract (EGb 761) prevents the ischemic brain injury-induced decrease in parvalbumin expression

Sung JH, Shah FA, Cho EH, Gim SA, Jeon SJ, Kim KM, Kim YM, Kim MO, Koh PO

Ginkgo biloba extract (EGb 761) exerts a neuroprotective effect against ischemic brain injury through an anti-apoptotic mechanism. Parvalbumin is a calcium buffering protein that plays an important role in modulating...
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