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Interaction of the mec Regulator Genes in Methicillin Resistant Staphylococcus

Choi Y, Lim IS, Shim TS, Lee MK, Park AJ

  • KMID: 2207820
  • J Korean Pediatr Soc.
  • 1998 Sep;41(9):1224-1233.
PURPOSE: Low-affinity penicillin-binding protein PBP 2a encoded by mecA is closely related to methicillin resistance in staphylococci, and the expression of PBP 2a is controlled by regulator elements encoded by...
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Distribution of mec Regulator Genes in Methicillin - Resistant Staphylococci

Cho DT, Lim DG, Kim JM

  • KMID: 1540522
  • J Korean Soc Microbiol.
  • 1997 Jun;32(3):275-284.
In order to understand the role of mec regulator genes in the evolution of methicillin-resistant S. aureus (MRSA), the distribution of the mec regulator genes among the 66 clinical isolates...
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Analysis of X irradiation related genes in HL60 cells using cDNA microarray

Park KU, Hwang MS, Suh SI, Suh MH, Kwon TK, Park JW, Cho JW, Choi EJ, Baek WK

  • KMID: 2146874
  • J Korean Soc Microbiol.
  • 2000 Aug;35(4):299-308.
Recently developed cDNA microarray or DNA chip technology allows expression monitoring of expression of hundreds and thousands of genes simultaneously and provides a format for identifying genes as well as changes in their...
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Localization of Nur77 mRNA in mouse Tests by in Situ Hybridization

Kim SJ, Chung DY, Kim YS, Niederberger CS, Lamb DJ

  • KMID: 2058571
  • J Korean Androl Soc.
  • 1995 Jan;13(1):1-5.
By identifying the mRNA products of stage-and cell-specific gene expression directly in histologic specimens, in hybridization provides a powerful tool to demonstrate the cellular mechanisms regulating spermatogenesis. Nur77 is...
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Expression Change of Complement Regulator Genes of the Human Astrocytoma Cell Line after A beta1-42 and Interferon Gamma Administration

Choi YS, Kim SH

  • KMID: 2338935
  • J Korean Geriatr Soc.
  • 2008 Dec;12(4):235-245.
BACKGROUND: We determined the changes of complement regulator gene expression in the amyloid-beta1-42(A beta1-42) and interferon-gamma(IFN-gamma)-stimulated human astrocytoma cell line. METHODS: The human astrocytoma cell line, U373MG, was stimulated with IFN-gamma(62.5-1,000U/ml)...
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Clonal analysis of methicillin-resistant Staphylococcus aureus strains in Korea

Kim J, Seol SY, Cho DT

  • KMID: 2146878
  • J Korean Soc Microbiol.
  • 2000 Jun;35(3):215-224.
In this study, the distribution of the mec regulator genes and the presence of the mutation in mecI gene and mec promoter region among 50 MRSA clinical isolates derived from a single...
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Changes of RAD50 and p53 Expression in Ultraviolet B-Irradiated Skin

Lee SC, Pyo WS, Lee JE, Won YH

  • KMID: 2086329
  • Korean J Dermatol.
  • 2000 Feb;38(2):213-220.
BACKGROUND: Ultraviolet irradiation causes various changes in cells or tissues including DNA damage, which results in changes of cell cycling, mutation and cell death such as apoptosis or necrosis. p53 has been...
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Cystic Fibrosis: Case Report

Park SH, Lee HJ, Kim JH, Park CH

Cystic fibrosis is a autosomal recessive genetic disease. Among Caucasians, it is the most common cause of pulmonary insufficiency during the first three decades of life. The prevalence of cystic...
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Estimation of the Genetic Substitution Rate of Hanwoo and Holstein Cattle Using Whole Genome Sequencing Data

Lee YS, Shin D

Despite the importance of mutation rate, some difficulties exist in estimating it. Next-generation sequencing (NGS) data yields large numbers of single-nucleotide polymorphisms, which can make it feasible to estimate substitution...
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High-concentration Epigallocatechin Gallate Treatment Causes Endoplasmic Reticulum Stress-mediated Cell Death in HepG2 Cells

Ahn JI, Jeong KJ, Ko MJ, Shin HJ, Chung HJ, Jeong HS

  • KMID: 2053228
  • Genomics Inform.
  • 2009 Jun;7(2):97-106.
Epigallocatechin gallate (EGCG), a well-known antioxidant molecule, has been reported to cause hepatotoxicity when used in excess. However, the mechanism underlying EGCG-induced hepatotoxicity is still unclear. To better understand the...
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Expression of Complement Regulator Genes in Abeta1-42 Stimulated Human Neuroblastoma Cell

Choi YS, Lee KS, Kim SH

  • KMID: 2343063
  • J Korean Neurol Assoc.
  • 2003 Oct;21(5):513-520.
BACKGROUND: Endogenous complement inhibitors in the brain may protect against the neuroinflammation in Alzheimer's disease. Human neuroblastoma cells were stimulated by Abeta1 - 4 2 to investigate whether the expression...
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A case of cystic fibrosis presented with meconium ileus in a female neonate

Hwang IO, Lee ES

Meconium ileus (MI) is the earliest clinical manifestation of cystic fibrosis (CF) in infants. It arises from the intraluminal accumulation of highly viscid, protein-rich meconium, typically present in the terminal...
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Molecular perspective of iron uptake, related diseases, and treatments

Shokrgozar N, Golafshan

Iron deficiency anemia and anemia of chronic disorders are the most common types of anemia. Disorders of iron metabolism lead to different clinical scenarios such as iron deficiency anemia, iron...
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Cystic fibrosis of pancreas and nephrotic syndrome: a rare association

Kelekci S, Karabel M, Ece A, Sen V, Gunes A, Yolbas I, Sahin C

Cystic fibrosis (CF) is a genetic disease with autosomal recessive inheritance and is common in Caucasian people. The prevalence of this disease is between 1/2,000 and 1/3,500 live births, and...
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Genetic syndromes associated with overgrowth in childhood

Ko JM

Overgrowth syndromes comprise a diverse group of conditions with unique clinical, behavioral and molecular genetic features. While considerable overlap in presentation sometimes exists, advances in identification of the precise etiology...
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Hemolytic uremic syndrome

Park HW

The hemolytic uremic syndrome (HUS) is a rare disease of microangiopathic hemolytic anemia, low platelet count and renal impairment. HUS usually occurs in young children after hemorrhagic colitis by shigatoxin-producing...
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Reactive Oxygen Species Production, Expression of Complement Regulator Genes and Phagocytosis in the Murine Microglial Cell after Administration of Beta-Amyloid(A beta1-42) Protein

Choi YS, Lee KS, Kim SH

  • KMID: 1626985
  • J Korean Neurol Assoc.
  • 2005 Feb;23(1):88-95.
BACKGROUND: Microglia is a primary cellular component of neuritic plaques in Alzheimer's disease. Beta amyloid deposits attract microglia and activate them to produce inflammatory mediators. The objectives of this study...
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Optimized Internal Control and Gene Expression Analysis in Epstein-Barr Virus-Transformed Lymphoblastoid Cell Lines

Nam HY, Kim HR, Shim SM, Lee JE, Kim JW, Park HK, Han BG, Jeon JP

  • KMID: 1806238
  • Genomics Inform.
  • 2011 Sep;9(3):127-133.
The Epstein-Barr virus-transformed lymphoblastoid cell line (LCL) is one of the major genomic resources for human genetics and immunological studies. Use of LCLs is currently extended to pharmacogenetic studies to...
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Gene-expression profiling of titanium-cell interaction

Kim CS, Hwang JW, Ryu JJ, Shin SW, Sohn SH, Kim KN, Kim MK

  • KMID: 2000734
  • J Korean Acad Prosthodont.
  • 2005 Jun;43(3):393-408.
STATEMENT OF PROBLEM: In the process of bone formation, titanium (Ti) surface roughness is an important factor modulating osteoblastic function. PURPOSE: This study was carried out to determine the effect...
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Expression of CDK inhibitor (CDI) p57 and bcl-2 mRNA during follicular development and follicular atresia in the rat ovary

Cho GJ, Koh PO, Kwak SD, Kim MO, Lee BH, Choi WS, Baik SH

  • KMID: 1530096
  • Korean J Anat.
  • 1998 Jun;31(3):361-370.
In mammals, the ovary proceeds follicular development and atresia during the reproductive cycle. Follicular atresia occurs through apoptosis, programmed cell death (PCD) which is mediated by gene controlling apoptosis and...
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