Korean J Pediatr.  2013 Oct;56(10):456-458. 10.3345/kjp.2013.56.10.456.

Cystic fibrosis of pancreas and nephrotic syndrome: a rare association

• Kelekci S
• Karabel M
• Ece A
• Sen V
• Gunes A
• Yolbas I
• Sahin C

• KMID: 1712454
• DOI: http://doi.org/10.3345/kjp.2013.56.10.456

Abstract

Cystic fibrosis (CF) is a genetic disease with autosomal recessive inheritance and is common in Caucasian people. The prevalence of this disease is between 1/2,000 and 1/3,500 live births, and the incidence varies between populations. Although the CF transmembrane conductance regulator gene is expressed in the kidneys, renal involvement is rare. With advances in the treatment of CF, life expectancy has increased, and some previously unobserved disease associations are now seen in patients with CF. It is important to follow patients with CF for possible abnormalities that may accompany CF. In this paper, we present two rare cases of CF accompanied by nephrotic syndrome.

Keyword

Cystic fibrosis; Nephrotic syndrome; Child

MeSH Terms

Child
Cystic Fibrosis*
Genes, Regulator
Humans
Heredity
Incidence
Kidney
Life Expectancy
Nephrotic Syndrome*
Pancreas*
Prevalence