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Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor

Seong I, Kim J

BACKGROUND: Melanocortin-1 receptor (Mc1r), a key signaling receptor for melanogenesis, has been reported to mediate migration of B16F10 melanoma cells. Interestingly, this activity appears to be a part of the...
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Regulation of Gene Expression in Oocyte Growth and Maturation

Lee KA

No abstract available.
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Regulation of gonadotropin releasing hormone receptor mRNA expression in cultured rat granulosa cells

Park Y, Kam K, Cheon M, Ryu K

The homologous regulation of pituitary Gonadotropin Releasing Hormone Receptor (GnRH-R) mRNA expression by GnRH has been well demonstrated. However, the regulation of the ovarian GnRH-R is poorly...
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Regulation of Gene Expression in Murine Renal Cell Carcinoma Cells Growing in Ectopic or Orthotopic Organs of Syngenic Mice

Jung YS, Ahn KS, Kim J, Lee H, Yoon SS

  • KMID: 2175028
  • J Korean Cancer Assoc.
  • 2000 Jun;32(3):619-628.
PURPOSE: The biologic behavior of tumor cells is partially controlled by the microenvironment. We investigated the expression levels of several genes involved in metastasis and drug response in RENCA cells growing in...
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Cholera toxin mediated regulation of the expression of Gq alpha and G11 alpha GTP binding proteins

Shah BH

  • KMID: 1029937
  • Exp Mol Med.
  • 1999 Jun;31(2):89-94.
Previously it has been shown that persistent activation of the stimulatory adenylyl cyclase pathway with cholera toxin (CT) downregulates the Gs alpha polypeptide (80%) in a cAMP-independent manner in C6 glioma cells...
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Induction of fibronectin gene expression by inhibitors of protein phosphatase type 2B in normal and transformed fibroblasts

Rhew JH, Shin YA, Lee BH, Park RW, Kim IS

  • KMID: 1029934
  • Exp Mol Med.
  • 1999 Jun;31(2):71-75.
Two intracellular signal pathways mediated by cAMP and protein kinase C (PKC) were involved in the regulation of FN gene expression (Lee et al., Exp. Mol. Med. 30: 240, 1998). In this...
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Regulation of fibronectin gene expression by cyclic AMP and phorbol myristate acetate in HT-1080 human fibrosarcoma cells

Lee BH, Park RW, Kim IS

  • KMID: 755015
  • Exp Mol Med.
  • 1998 Dec;30(4):240-245.
We studied the regulation of fibronectin (FN) gene expression by cAMP and phorbol-12-myristate-13-acetate (PMA) in HT-1080 human fibrosarcoma cells. Dibutyryl cAMP increased FN synthesis and mRNA levels, while PMA inhibited...
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