- Regulation of Gene Expression in Oocyte Growth and Maturation
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Lee KA
- KMID: 2200652
- J Korean Soc Endocrinol.
- 2006 Feb;21(1):11-13.
- doi: 10.3803/jkes.2006.21.1.11
No abstract available. -
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- Epigenetic Regulation of Cytokine Gene Expression in T Lymphocytes
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Lee CG, Sahoo A, Im SH
- KMID: 1758557
- Yonsei Med J.
- 2009 Jun;50(3):322-330.
- doi: 10.3349/ymj.2009.50.3.322
The developmental program of T helper and regulatory T cell lineage commitment is governed by both genetic and epigenetic mechanisms. The principal events, signaling pathways and the lineage determining factors... -
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- The upstream sequence of Mycobacterium leprae 18-kDa gene confers transcription repression activity in orientation-independent manner
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Kim HB, You JC
- KMID: 1103317
- Exp Mol Med.
- 2004 Dec;36(6):510-514.
In order to understand the role of the upstream region of the Mycobacterium leprae 18-kDa gene on the gene regulation, the region was divided into two at the -50 position... -
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- Understanding Disease Susceptibility through Population Genomics
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Han S, Lee J, Kim S
- KMID: 2053302
- Genomics Inform.
- 2012 Dec;10(4):234-238.
- doi: 10.5808/GI.2012.10.4.234
Genetic epidemiology studies have established that the natural variation of gene expression profiles is heritable and has genetic bases. A number of proximal and remote DNA variations, known as expression... -
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- DNA Methylation of Gene Expression in Acanthamoeba castellanii Encystation
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Moon EK, Hong Y, Lee HA, Quan FS, Kong HH
- KMID: 2379412
- Korean J Parasitol.
- 2017 Apr;55(2):115-120.
- doi: 10.3347/kjp.2017.55.2.115
Encystation mediating cyst specific cysteine proteinase (CSCP) of Acanthamoeba castellanii is expressed remarkably during encystation. However, the molecular mechanism involved in the regulation of CSCP gene expression remains unclear. In... -
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- Induction of fibronectin gene expression by inhibitors of protein phosphatase type 2B in normal and transformed fibroblasts
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Rhew JH, Shin YA, Lee BH, Park RW, Kim IS
- KMID: 1029934
- Exp Mol Med.
- 1999 Jun;31(2):71-75.
Two intracellular signal pathways mediated by cAMP and protein kinase C (PKC) were involved in the regulation of FN gene expression (Lee et al., Exp. Mol. Med. 30: 240, 1998). In this... -
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- Cytokine regulation of expression of class I MHC antigens
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Raval A, Puri N, Rath PC, Saxena RK
- KMID: 754981
- Exp Mol Med.
- 1998 Mar;30(1):1-13.
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- Alu and L1 Retroelements Are Correlated with the Tissue Extent and Peak Rate of Gene Expression, Respectively
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Kim TM, Jung YC, Rhyu MG
- KMID: 1778557
- J Korean Med Sci.
- 2004 Dec;19(6):783-792.
- doi: 10.3346/jkms.2004.19.6.783
We exploited the serial analysis of gene expression (SAGE) libraries and human genome database in silico to correlate the breadth of expression (BOE; housekeep-ing versus tissue-specific genes) and peak rate... -
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- Transcriptional repression of type I procollagen genes during adipocyte differentiation
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Yi TG, Choi HM, Park RW, Sohn KY, Kim IS
- KMID: 1457541
- Exp Mol Med.
- 2001 Dec;33(4):269-275.
Adipocyte differentiation is a very complex process in which whole-cell changes are accompanied. Among them, type I procollagen gene has been shown to specifically decrease during adipocyte differentiation; however, little... -
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- Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor
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Seong I, Kim J
- KMID: 2169425
- Endocrinol Metab.
- 2014 Jun;29(2):179-184.
- doi: 10.3803/EnM.2014.29.2.179
BACKGROUND: Melanocortin-1 receptor (Mc1r), a key signaling receptor for melanogenesis, has been reported to mediate migration of B16F10 melanoma cells. Interestingly, this activity appears to be a part of the... -
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- Regulation of fibronectin gene expression by cyclic AMP and phorbol myristate acetate in HT-1080 human fibrosarcoma cells
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Lee BH, Park RW, Kim IS
- KMID: 755015
- Exp Mol Med.
- 1998 Dec;30(4):240-245.
We studied the regulation of fibronectin (FN) gene expression by cAMP and phorbol-12-myristate-13-acetate (PMA) in HT-1080 human fibrosarcoma cells. Dibutyryl cAMP increased FN synthesis and mRNA levels, while PMA inhibited... -
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- Down-regulation of human FEN-1 gene expression during differentiation of promyelocytic leukemia cells
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Kim IS
- KMID: 755017
- Exp Mol Med.
- 1998 Dec;30(4):252-256.
Flap endo/exonuclease-1 (FEN-1) recognizes 5'-flap DNA structures that have been proposed to be important intermediates in DNA replication, repair and recombination, and cleaves the double strand-single strand junction of flap ... -
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- Aberrantly expressed microRNAs in the context of bladder tumorigenesis
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Lee JY, Ryu DS, Kim WJ, Kim SJ
- KMID: 2426517
- Investig Clin Urol.
- 2016 Jun;57(Suppl 1):S52-S59.
- doi: 10.4111/icu.2016.57.S1.S52
MicroRNAs (miRNAs), small noncoding RNAs 19-22 nucleotides in length, play a major role in negative regulation of gene expression at the posttranscriptional level. Several miRNAs act as tumor suppressors or... -
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- 14-3-3epsilon protein increases matrix metalloproteinase-2 gene expression via p38 MAPK signaling in NIH3T3 fibroblast cells
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Lee EK, Lee YS, Lee H, Choi CY, Park SH
- KMID: 1058019
- Exp Mol Med.
- 2009 Jul;41(7):453-461.
- doi: 10.3858/emm.2009.41.7.050
One of the 14-3-3 protein isoforms, 14-3-3epsilon, was previously shown to be increased during skin aging. We suggest here a possible role for the 14-3-3epsilon protein in skin aging by... -
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- Epigenetic regulation and chromatin remodeling in learning and memory
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Kim S, Kaang BK
- KMID: 2367527
- Exp Mol Med.
- 2017 Jan;49(1):e281.
- doi: 10.1038/emm.2016.140
Understanding the underlying mechanisms of memory formation and maintenance has been a major goal in the field of neuroscience. Memory formation and maintenance are tightly controlled complex processes. Among the... -
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- Regulation of NFATc1 in Osteoclast Differentiation
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Kim JH, Kim N
- KMID: 2170050
- J Bone Metab.
- 2014 Nov;21(4):233-241.
- doi: 10.11005/jbm.2014.21.4.233
Osteoclasts are unique cells that degrade the bone matrix. These large multinucleated cells differentiate from the monocyte/macrophage lineage upon stimulation by two essential cytokines, macrophage colony-stimulating factor (M-CSF) and receptor... -
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- miR-139 modulates MCPIP1/IL-6 expression and induces apoptosis in human OA chondrocytes
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Makki MS, Haqqi TM
- KMID: 2160620
- Exp Mol Med.
- 2015 Oct;47(10):e189.
- doi: 10.1038/emm.2015.66
IL-6 is an inflammatory cytokine and its overexpression plays an important role in osteoarthritis (OA) pathogenesis. Expression of IL-6 is regulated post-transcriptionally by MCPIP1. The 3' untranslated region (UTR) of... -
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- Interferon-gamma upregulates the stromelysin-1 gene expression by human skin fibroblasts in culture
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Lee KS, Ryoo YW, Song JY
- KMID: 754989
- Exp Mol Med.
- 1998 Jun;30(2):59-64.
The equilibrium between deposition and degradation of extracellular matrix(ECM) is essential to normal tissue development and repair of wound or inflammatory responses. It has recently become apparent that several cytokines and growth factors... -
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- Gene Expression Profiling of Breast Cancers with Emphasis of beta-Catenin Regulation
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Roh MS, Hong SH, Jeong JS, Kwon HC, Kim MC, Cho SH, Yoon JH, Hwang TH
- KMID: 1733489
- J Korean Med Sci.
- 2004 Apr;19(2):275-282.
- doi: 10.3346/jkms.2004.19.2.275
To gain molecular understanding of carcinogenesis of breast cancer, gene expression profiles were analyzed using cDNA microarray representing 4,600 cDNAs in 10 breast cancer samples and the adjacent noncancerous breast... -
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- Regulation of ATP-citrate lyase gene transcription
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Kim KS, Kang JG, Moon YA, Park SW, Kim YS
- KMID: 699895
- Yonsei Med J.
- 1996 Jun;37(3):214-224.
- doi: 10.3349/ymj.1996.37.3.214
It has been suggested that glucose metabolites and insulin are the most important factors inducing ATP-citrate lyase (ACL) by a high carbohydrate diet. We have used a primary culture of... -
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