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Novel Molecules Regulating Energy Homeostasis: Physiology and Regulation by Macronutrient Intake and Weight Loss

Gavrieli A, Mantzoros

Excess energy intake, without a compensatory increase of energy expenditure, leads to obesity. Several molecules are involved in energy homeostasis regulation and new ones are being discovered constantly. Appetite regulating...
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Letter: Association between Serum Dipeptidyl Peptidase-4 Concentration and Obesity-Related Factors in Health Screen Examinees (J Obes Metab Syndr 2017;26:188-96)

Koh G

No abstract available.
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Response: Association between Serum Dipeptidyl Peptidase-4 Concentration and Obesity-Related Factors in Health Screen Examinees (J Obes Metab Syndr 2017;26:188-96)

Lee JY, Jang BK, Song MK, Kim HS, Kim MK

No abstract available.
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A Case of AVP Dependent Bilateral Macronodular Adrenal Hyperplasia

Kim HJ, Kim SH, Rhee YM, Kim SE, Ahn CW, Cha BS, Kim KR, Lee HC, Huh KB, Lim SK

  • KMID: 2200008
  • J Korean Soc Endocrinol.
  • 2002 Aug;17(4):603-609.
Adrenocorticotropin (ACTH) independent bilateral macronodular adrenal hyperplasia (AIMAH) is a rare form of Cushing's syndrome, in which unique endocrinological, clinical and histopathological features have been described. In AIMAH, cortisol secretion...
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Factors Related to Blood Intact Incretin Levels in Patients with Type 2 Diabetes Mellitus

Yoo S, Yang EJ, Koh G

BACKGROUND: We performed this study to identify factors related to intact incretin levels in patients with type 2 diabetes mellitus (T2DM). METHODS: We cross-sectionally analyzed 336 patients with T2DM. Intact glucagon-like...
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The Role of the Sweet Taste Receptor in Enteroendocrine Cells and Pancreatic beta-Cells

Kojima I, Nakagawa Y

The sweet taste receptor is expressed in taste cells located in taste buds of the tongue. This receptor senses sweet substances in the oral cavity, activates taste cells, and transmits...
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Correlation of Glypican-4 Level with Basal Active Glucagon-Like Peptide 1 Level in Patients with Type 2 Diabetes Mellitus

Lee SA, Koh G, Cho SJ, Yoo SY, Chin SO

BACKGROUND: Previous studies have reported that glypican-4 (GPC4) regulates insulin signaling by interacting with insulin receptor and through adipocyte differentiation. However, GPC4 has not been studied with regard to its...
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Glucose-Dependent Insulinotropic Peptide Level Is Associated with the Development of Type 2 Diabetes Mellitus

Suh S, Kim MY, Kim SK, Hur KY, Park MK, Kim DK, Cho NH, Lee MK

BACKGROUND: Incretin hormone levels as a predictor of type 2 diabetes mellitus have not been fully investigated. Therefore, we measured incretin hormone levels to examine the relationship between circulating incretin...
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Treatment of Type 1 Diabetes through Genetically Engineered K-cell Transplantation in a Mouse Model

Sim JY, Kim JH, Ahn YB, Song KH, Han JH, Cha BY, Lee SK, Moon SD

BACKGROUND: K-cells function as targets for insulin gene therapy. In a previous study, we constructed EBV-based plasmids expressing rat preproinsulin controlled by glucose-dependent insulinotropic polypeptide promoters. In the present study,...
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Calcium-sensing receptor-mediated L-tryptophan-induced secretion of cholecystokinin and glucose-dependent insulinotropic peptide in swine duodenum

Zhao X, Xian Y, Wang C, Ding L, Meng X, Zhu W, Hang S

This study aimed to elucidate the effect of tryptophan (Trp) on gut hormone secretion as well as the roles of the calcium-sensing receptor (CaSR) and its downstream signaling pathway in...
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Improving Effect of the Acute Administration of Dietary Fiber-Enriched Cereals on Blood Glucose Levels and Gut Hormone Secretion

Kim EK, Oh TJ, Kim LK, Cho YM

Dietary fiber improves hyperglycemia in patients with type 2 diabetes through its physicochemical properties and possible modulation of gut hormone secretion, such as glucagon-like peptide 1 (GLP-1). We assessed the...
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Glucose-dependent Insulin Secretion from Genetically Engineered K-cells Using EBV-based Episomal Vector

Kim JH, Moon SD, Ko SH, Ahn YB, Song KH, Lim HS, Lee SK, Yoo SJ, Son HS, Yoon KH, Cha BY, Son HY, Kim SJ, Han JH

BACKGROUND: Type 1 diabetes mellitus is an autoimmune disease resulting in destruction of the pancreatic beta cells. Insulin gene therapy for these patients has been vigorously researched. The strategy for...
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