- Therapeutic effect of gabexate mesilate as therapy for childhood DIC
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Jung JW, Park SH, Kang SH, Lyu CJ, Yang CH, Kim KY
- KMID: 1688083
- Korean J Hematol.
- 1991 Jun;26(1):93-101.
No abstract available. -
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- Inhibition of prostaglandin F2 and thromboxane B2 synthesis in electrically injured tissue by flurbiprofen, prednisolone and gabexate mesilate
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Cho BC, Kim IK, Byun JS, Baik BS
- KMID: 2119218
- J Korean Soc Plast Reconstr Surg.
- 1991 Jan;18(1):75-87.
No abstract available. -
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- Effect of Gabexate Mesilate on Exocrine Secretion of Pancreas in Rats
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Choi SK, Kim GT, Park CH, Rew JS, Kim SJ, Yoon CM
- KMID: 2275045
- Chonnam Med J.
- 1997 Jun;33(1):47-54.
Gabexate mesilate is a synthetic compound of 417 daltons that is not antigenic and diffuse easily. Gabexate is a serine protease inhibitor, with effect on trypsin, kallikrein, plasmin and thrombin.... -
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- Nafamostat for Prophylaxis against Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis Compared with Gabexate
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Chang JH, Lee IS, Kim HK, Cho YK, Park JM, Kim SW, Choi MG, Chung IS
- KMID: 2284064
- Gut Liver.
- 2009 Sep;3(3):205-210.
BACKGROUND/AIMS: The protease inhibitors, nafamostat and gabexate, have been used to prevent pancreatitis related to endoscopic retrograde cholangiopancreatography (ERCP). In vitro, nafamostat inhibits the pancreatic protease activities 10-100 times more... -
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- Gabexate for the Prevention of Pancreatic Complications Following Endoscopic Retrograde Cholangiopancreatography
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Cho JH, Kang SJ, Jung UT
- KMID: 2014244
- Korean J Gastrointest Endosc.
- 2000 Sep;21(3):730-734.
BACKGROUND/AIMS: Gabexate, a protease inhibitor, has been known to prevent pancreatic damage following ERCP. We conducted a prospective and randomized study to assess the preventive effect of gabexate. Methods: Of... -
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- Effect of Gabexate Mesilate on Exocrine Pancreatic Secreation in Rats
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Kim SJ, Yoon CM, Choi SK, Kim HS, Cho CY, Rew JS
- KMID: 2304703
- Korean J Gastroenterol.
- 1998 Sep;32(3):376-382.
BACKGROUND AND AIMS: Gabexate mesilate, a serine protease inhibitor, is a synthetic compound which is not antigenic and diffuses easily. We have investigated the effect of gabexate mesilate on exocrine... -
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- Could Nafamostat or Gabexate Prevent the Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis?
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Kwon YH, Kim JY, Lee SJ, Jang SY, Park HW, Yang HM, Jung MK, Jeon SW, Cho CM, Tak WY, Kweon YO, Kim SK
- KMID: 1245208
- Korean J Gastroenterol.
- 2012 Mar;59(3):232-238.
- doi: 10.4166/kjg.2012.59.3.232
BACKGROUND/AIMS: ERCP is the most common procedure for the diagnosis and treatment of bile duct and pancreatic disease, but Post-ERCP pancreatitis makes poor outcome in some cases. The protease inhibitors,... -
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- Risk Factors for Post-ERCP Pancreatitis after Needle Knife Sphincterotomy following Repeated Probing
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Lee JK, Park JK, Lee SH, Yoon WJ, Lee KH, Ryu JK, Kim YT, Yoon YB
- KMID: 2244063
- Korean J Gastrointest Endosc.
- 2006 Apr;32(4):266-270.
BACKGROUND/AIMS: Needle knife sphincterotomy (NKS) following repeated probing due to difficult cannulation during ERCP increase the risk of post-ERCP pancreatitis. However, the risk factors for post-ERCP pancreatitis are not well-known.... -
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- The Use of Gabexate Mesylate and Ulinastatin for the Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis
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Yoo YW, Cha SW, Kim A, Na SY, Lee YW, Kim SH, Lee HI, Lee YJ, Yang HW, Jung SH
- KMID: 2284273
- Gut Liver.
- 2012 Apr;6(2):256-261.
BACKGROUND/AIMS: Acute pancreatitis is a common complication of endoscopic retrograde cholangiopancreatography (ERCP). Only a few pharmacologic agents have been shown to have potential efficacy for the prophylactic treatment of post-ERCP... -
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- The Effects of Gabexate Mesilate on the Ishemia-Reperfusion Injury in the Rabbit Liver
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Shin YD, Lee SM, Ko YG, Lee KH, Koh SH, Hong SW, Oh SM
- KMID: 1895788
- J Korean Surg Soc.
- 2001 Dec;61(6):553-559.
PURPOSE: Ischemia-reperfusion is an important pathologic process that leads to impairment of the liver after major surgery. Ischmia-reperfusion injury includes both hypoxia and an inflammatory response associated with reperfusion; the... -
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- A Study on the Effect of Combination Therapy with Anti - Thrombin III and Gabexate Mesilate in Premature Infants for Disseminated Intravascular Coagulation
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Jung JA, Lee YA, Lee YH, Choi AH
- KMID: 2188762
- J Korean Soc Neonatol.
- 1999 May;6(1):71-77.
PURPOSE: Both antithrombin III(ATIII) and Gabexate mesilate(Foy) are effective for the treatment of disseminated intravascular coagulation(DIC). However, their mechanisms of action are slightly different, and combined effect of ATIII and... -
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- Effect of Protease Inhibitor on the Ischemia-reperfusion Injury to the Rat Liver
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Jung SE, Yun IJ, Youn YK, Lee JE, Ha J, Noh DY, Lee KK, Kim SJ, Oh SK, Choe KJ
- KMID: 1940346
- J Korean Surg Soc.
- 1998 May;54(5):613-620.
BACKGROUND: Liver failure due to ischemia-reperfusion injury is a serious problem in liver transplantation and radical wide resection of the liver. This injury is believed to be closely related to... -
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- Effects of Gabexate Mesilate (Foy(R)) on Endotoxin-Induced Acute Lung Injury in Rabbit
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Kwak SH, Jung G, Choi CH, Kim CM, Bae HB, Chung ST, Jeong CY
- KMID: 1894344
- Korean J Anesthesiol.
- 2005 Dec;49(6):S26-S34.
- doi: 10.4097/kjae.2005.49.6.S26
BACKGROUND: This study was to clarify the effects of gabexate mesilate (Foy(R)), a synthetic protease inhibitor, on endotoxin induced acute lung injury in rabbit. METHODS: Animals were randomly assigned to one... -
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- Changing patterns of Pancreatic enzyme after Distal Gastrectomy and the Effect of Protease Inhibitor Treatment
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Oh ST, Kim WS, Kim BS
- KMID: 2206235
- J Korean Surg Soc.
- 1997 Jun;52(6):846-851.
We have reported that serum amylase and lipase level elevate immediately after total gastrectomy independent to whether the pancreas is manipulated or not. Although we found high levels of amylase... -
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- Effects of Gabexate Mesilate for the Prevention of Pancreatic Damage Related to ERCP
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Jeen YT, Chun HJ, Lee JW, Hur BW, Lee HS, Song CW, Um SH, Lee SW, Choi JH, Kim CD, Ryu HS, Hyun JH, Kang CD
- KMID: 1865461
- Korean J Gastrointest Endosc.
- 2000 Jul;21(1):534-542.
BACKGROUND/AIMS: Recent studies reported that 1g of gabexate mesilate (GM) was effective in preventing endoscopic retrograde cholangiopancreatography (ERCP)-related pancreatic damage. The aim of this study was to evaluate the effectiveness... -
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- The Effect of Gabexate Mesylate in vivo Model of Intimal Hyperplasia on the Activity of Matrix Metalloproteinase and Proliferation of Smooth Muscle Cell
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Yang HC, Kwun WH, Suh BY, Kwun KB
- KMID: 1941116
- J Korean Soc Vasc Surg.
- 2003 May;19(1):13-21.
PURPOSE: Migration and proliferation of vascular smooth muscle cells (VSMCs) are important for neointimal formation after arterial injury. Migration of VSMCs requires the degradation of basement membrane and extracellular matrix... -
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- Effects of Propofol and Gabexate Mesilate (Foy) on Endotoxin-induced Acute Lung Injury in Rabbit
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Chung SS, Bae HB, Kim SJ, Jeong CW, Chung HJ, Li M, Kwak SH
- KMID: 2172297
- Chonnam Med J.
- 2008 Dec;44(3):169-176.
- doi: 10.4068/cmj.2008.44.3.169
This study was to clarify the effects of propofol and gabexate mesilate (foy), a synthetic protease inhibitor, on endotoxin induced-acute lung injury in rabbit. Animals were randomly assigned to one... -
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- Pancreaticopleural Fistula with Hemothorax
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Sul YH, Shin HS, Lee KH, Chun KS, Song IS
- KMID: 2096542
- J Korean Surg Soc.
- 2009 Mar;76(3):187-191.
- doi: 10.4174/jkss.2009.76.3.187
Pancreaticopleural fistula is an uncommon complication of chronic pancreatitis. We report a case of pancreaticopleural fistula that was presented with right-sided hemothorax. A 49-year-old male with a history of chronic... -
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- Application of Gabexate Mesylate IC against MMP - 9 Using ex vivo Model in Gastric Cancer: Prognostic Factor and Selection Criteria for Anti - MMP Treatment
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Moon YW, Yang H, Jung HC, Rha SY, Kim TS, Yoo NC, Noh SH, Roh JK, Min JS, Kim BS, Chung HC
- KMID: 2137106
- J Korean Cancer Assoc.
- 2000 Feb;32(1):7-18.
PURPOSE: Among the many biological characteristics of cancer, matrix metalloproteinases(MMPs) are essential for tumor invasion and metastasis. The correction of the imbalance between MMPs and tissue inhibitors of matrix metalloproteinase... -
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- Appropriate Premedication for Prevention on Post-ERCP Pancreatitis: A Randomized and Prospective Study
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Yi SY
- KMID: 1964006
- Ewha Med J.
- 2006 Sep;29(2):89-97.
- doi: 10.12771/emj.2006.29.2.89
OBJECTIVES: Pancreatitis is the most common and serious complication of ERCP. On the basis of several reports, corticosteroid, octreotide, or calcium channel blocker might be effective in this regard. The... -
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