- Efficacy and Safety of a Pressurized Metered-Dose Inhaler in Older Asthmatics: Comparison to a Dry Powder Inhaler in a 12-Week Randomized Trial
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Woo SD, Ye YM, Lee Y, Lee SH, Shin YS, Park JH, Choi H, Lee HY, Shin HJ, Park HS
- KMID: 2471229
- Allergy Asthma Immunol Res.
- 2020 May;12(3):454-466.
- doi: 10.4168/aair.2020.12.3.454
PURPOSE: Asthma control in older asthmatics is often less effective, which may be attributed to small airway dysfunction and poor inhalation technique. We compared the efficacy of 2 inhalers (fluticasone... -
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- The Effects of Olfactory Training with Intranasal Corticosteroid Spray in Korean Patients with Olfactory Dysfunction
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Jung YD, Kim DS, Kang BJ, Shin SH, Ye MK
- KMID: 2465542
- J Rhinol.
- 2019 Nov;26(2):106-112.
- doi: 10.18787/jr.2019.26.2.106
BACKGROUND AND OBJECTIVES: Olfactory training is an alternative treatment based on modulation of the regeneration process of the olfactory system via repeated exposure to odors. Our study aimed to investigate... -
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- Efficacy and predictors of response to inhaled corticosteroid treatment for chronic cough
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Hong JY, Kim JH, Park S, Hwang YI, Jung KS, Jang SH
- KMID: 2448348
- Korean J Intern Med.
- 2019 May;34(3):559-568.
- doi: 10.3904/kjim.2017.291
BACKGROUND/AIMS: Inhaled corticosteroids (ICS) are a treatment of choice for eosinophilic airway diseases, but their efficacy for other causes of chronic cough is controversial. METHODS: We conducted a prospective observational study... -
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- Pharmacokinetic characteristics of fluticasone, salmeterol and tiotropium after concurrent inhalation
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Sunwoo J, Rhee SJ, Lee S, Lee SW, Jung J, Son H, Jang IJ
- KMID: 2386765
- Transl Clin Pharmacol.
- 2017 Jun;25(2):85-92.
- doi: 10.12793/tcp.2017.25.2.85
Chronic obstructive pulmonary disease (COPD) is a type of progressive, obstructive lung disease characterized by long-term poor airflow. The symptoms of COPD may be relieved and its progression delayed by... -
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- Assessment of leukotriene E4 in exhaled breath condensate as a marker of inflammation and therapeutic effect in allergic rhinitis children
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Kwak BO, Park YM
- KMID: 2368576
- Allergy Asthma Respir Dis.
- 2017 Jan;5(1):47-51.
- doi: 10.4168/aard.2017.5.1.47
PURPOSE: Recent studies have shown that the cysteinyl leukotriene (cysLT) of exhaled breath condensate (EBC) could be predictive of inflammatory status and effectiveness of treatment in allergic disease. The aim... -
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- Different anti-remodeling effect of nilotinib and fluticasone in a chronic asthma model
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Kang HS, Rhee CK, Lee HY, Yoon HK, Kwon SS, Lee SY
- KMID: 2382865
- Korean J Intern Med.
- 2016 Nov;31(6):1150-1158.
- doi: 10.3904/kjim.2015.002
BACKGROUND/AIMS: Inhaled corticosteroids are the most effective treatment currently available for asthma, but their beneficial effect against airway remodeling is limited. The tyrosine kinase inhibitor nilotinib has inhibitory activity against... -
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- Three-month Treatment Response and Exacerbation in Chronic Obstructive Pulmonary Disease
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Lee JS, Rhee CK, Yoo KH, Lee JH, Yoon HI, Kim TH, Kim WJ, Lee J, Lim SY, Park TS, Lee JS, Lee SW, Lee SD, Oh YM
- KMID: 2155447
- J Korean Med Sci.
- 2015 Jan;30(1):54-59.
- doi: 10.3346/jkms.2015.30.1.54
The aim of this study was to investigate relationships between acute exacerbation and Forced Expiratory Volume 1 second (FEV1) improvement after treatment with combined long-acting beta-agonist (LABA) and inhaled corticosteroid... -
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- Suppressive effects of long-term treatment with inhaled steroids on hypothalamic-pituitary-adrenal axis in asthma
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Sim DW, Choi IS, Kim SH
- KMID: 2262397
- Allergy Asthma Respir Dis.
- 2014 Sep;2(4):285-292.
- doi: 10.4168/aard.2014.2.4.285
PURPOSE: Long-term treatment with inhaled steroids (ICS), especially fluticasone that developed lately, may suppress the hypothalamic-pituitary-adrenal (HPA) axis. This study investigated the relationship between ICS use and HPA axis suppression... -
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- Improvement of Eosinophilic Otitis Media by Optimized Asthma Treatment
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Tanaka Y, Nonaka M, Yamamura Y, Tagaya E, Pawankar R, Yoshihara
- KMID: 2260338
- Allergy Asthma Immunol Res.
- 2013 May;5(3):175-178.
- doi: 10.4168/aair.2013.5.3.175
Eosinophilic otitis media (EOM) shows a very high rate of association with asthma, and intractable otitis media involves marked eosinophil infiltration into the middle ear. The middle ear space is... -
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- The Efficacy of Immediate Diet for Reducing Local Adverse Events of Inhaled Corticosteroid: A Pilot Study
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Lee MK, Lee WY, Yong SJ, Shin KC, Kim CW, Lee JH, Jung S, Jung YR, Kim HS, Yu TS, Kim SH
- KMID: 2319898
- Tuberc Respir Dis.
- 2012 Aug;73(2):93-99.
BACKGROUND: Local adverse events associated with inhaled corticosteroid use, including dysphonia, pharyngitis and oral candidiasis, can affect adherence for treatment. 'Mouth rinsing method' has been used for reducing local adverse... -
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- The role of inhaled and/or nasal corticosteroids on the bronchodilator response
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Lee JK, Suh DI, Koh YY
- KMID: 2280908
- Korean J Pediatr.
- 2010 Nov;53(11):951-956.
- doi: 10.3345/kjp.2010.53.11.951
BACKGROUND: To compare the profiles of the bronchodilator response (BDR) among children with asthma and/or allergic rhinitis (AR) and to determine whether BDR in these children is reduced by treatment... -
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- Effects of Smoking Cessation on Airflow Obstruction and Quality of Life in Asthmatic Smokers
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Jang AS, Park SW, Kim DJ, Uh S, Kim YH, Whang HG, Lim GI, Park CS
- KMID: 2260386
- Allergy Asthma Immunol Res.
- 2010 Oct;2(4):254-259.
- doi: 10.4168/aair.2010.2.4.254
PURPOSE: Smoking elicits airway inflammation and airflow obstruction in patients with asthma, even after smoking cessation. The aim of this study was to examine the effects of smoking cessation on... -
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- Comparison for the Effects of Triple Therapy with Salmeterol/Fluticasone Propionate and Tiotropium Bromide versus Individual Components in Patients of Severe COPD Combined with Bronchial Hyperresponsiveness
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Sohn JY, Kim SR, Park SJ, Lee HB, Lee YC, Rhee YK
- KMID: 2319294
- Tuberc Respir Dis.
- 2009 Dec;67(6):536-544.
BACKGROUND: A combination of salmeterol and fluticasone propionate (SFC) and tiotropium bromide (TIO) is commonly prescribed for COPD patients but there is little data on their effectiveness, particularly in COPD... -
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- The Efficacy of Inhaled Corticosteroid on Chronic Idiopathic Cough
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Han B, Jang SH, Kim YJ, Park S, Hwang YI, Kim DG, Kim CH, Hyun IG, Jung KS
- KMID: 2319279
- Tuberc Respir Dis.
- 2009 Nov;67(5):422-429.
BACKGROUND: The discomfort caused by chronic cough, that is persistent for more than 3 weeks, causes a number of patients to seek medical attention. However, the underlying disorder often remains... -
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- An open, Multi center, Randomized, Parallel Group Study to Compare the Effectiveness and Safety of Fluticasone Plus Tulobuterol Versus Twice the Dose of Fluticasone Alone in Asthmatic Children
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Jeon YH, Yang HJ, Yoo Y, Kim YH, Jeong JT, Lee HR, Pyun BY
- KMID: 2314940
- Pediatr Allergy Respir Dis.
- 2009 Jun;19(2):125-136.
PURPOSE: We aim to compare the effectiveness and safety of fluticasone propionate (Flt) plus tulobuterol (Hk) versus high-dose Flt alone in controlling asthma in children. METHODS: Fifty three children aged 4... -
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- Economic Evaluations of Alternative Inhaled Steroid Medications in Patients with Asthma
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- KMID: 2234477
- Korean J Asthma Allergy Clin Immunol.
- 2008 Mar;28(1):26-34.
BACKGROUND: Asthma requires enormous social costs and deteriorates quality of life. Inhaled corticosteroids (ICSs) including budesonide (BUD), fluticasone propionate (FP), and ciclesonide (CIC) are currently considered the standard therapy for... -
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- The Effects of Corticosteroids on IL-6, IL-8 and RANTES Production from RSV-infected Epithelial Cells
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- KMID: 2299655
- Korean J Asthma Allergy Clin Immunol.
- 2005 Dec;25(4):305-312.
BACKGROUND: RSV induces the production of cytokines and chemokines in airway epithelial cells. Corticosteroids (CSs) can inhibit the production. OBJECTIVE: We examined whether the inhibitory effect of CSs on cytokines and... -
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- Effects of Corticosteroids on RANTES Production in Human Bronchial Epithelial Cell with Respiratory Syncytial Virus Infection
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Lee EJ, Jeoun HJ, Yoon JS, Lee Y, Han JW, Lee JS
- KMID: 2314389
- Pediatr Allergy Respir Dis.
- 2005 Sep;15(3):290-299.
PURPOSE: Respiratory syncytial virus (RSV) which is the most common cause of bronchiolitis in infants is an important triggering factor of asthma exacerbation in children. This virus stimulates chemokine such... -
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- The Efficacy and Safety of Inhaled Steroid Therapy for Prevention of Recurrent Wheezing after Bronchiolitis
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Kim SR, Lim KH, Kim MJ, Kim YH, Jung JA, Yang S, Hwang IT, Lee HR
- KMID: 2314352
- Pediatr Allergy Respir Dis.
- 2004 Dec;14(4):392-401.
PURPOSE: The purpose of this study was to evaluate the efficacy and metabolism of inhaled steroids to prevent recurrent wheezing after bronchiolitis. METHODS: Sixty two patients were randomly divided into... -
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- Effect of Intranasal Corticosteroid Therapy for Perennial Nonallergic Rhinitis and Perennial Allergic Rhinitis
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Choi JM, sung MH, Lee SW, Bae YJ, Wang CW, Jung JA
- KMID: 2314335
- Pediatr Allergy Respir Dis.
- 2004 Sep;14(3):199-206.
PURPOSE: The efficacy of intranasal corticosteroids for the treatment of allergic rhinitis has been reported. But the efficacy of intranasal corticosteroids has not been compared between perennial nonallergic rhinitis (PNAR)... -
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