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Quantification of Cell-Free DNA: A Comparative Study of Three Different Methods

Jeon K, Lee J, Lee JS, Kim M, Kim HS, Kang HJ, Lee YK

BACKGROUND: Cell-free DNA (cfDNA) provides unique potential as a biomarker for cancer patients or in the field of prenatal care. Following extraction from plasma, cfDNA should be quantified before downstream...
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Requirement of ERK Activation in Hypoxia Induced Caspase Activation and Apoptosis of Cultured Tubular Cells

Ko GJ, Lee JW, Choi HM, Hyun YY, Ko YS, Jo SK, Cho WY, Kim HK

  • KMID: 2254155
  • Korean J Nephrol.
  • 2006 Mar;25(2):185-194.
BACKGOUND: Renal tubular epithelial cells are primary target for hypoxic injury. Hypoxia induced tubular cell apoptosis has been reported previously and thought to be important mechanism of renal dysfunction in...
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PREFABRICATION OF AURICLE WITH ABDOMINAL FLAP AND CARTILAGE IN RABBIT

Tark KC

  • KMID: 2119333
  • J Korean Soc Plast Reconstr Surg.
  • 1997 Mar;24(2):293-300.
Ear reconstruction with conventional modalities necessitates time consumming, expenses and multi-stage operations, a lot of time, and cost. Although single stage ear reconstruction with vascularized temporoparietal fascia has been developed,...
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Effects of the Immunoglobulins of Amyotrophic Lateral Sclerosis on Intracellular Calcium in PC12 Cells

Kim SH, Jung SJ, Park KS, Kim M, Kim J, Kim HJ, Lee KW

  • KMID: 2342858
  • J Korean Neurol Assoc.
  • 2000 Nov;18(6):728-734.
BACKGROUND: The motor neuronal death in amyotrophic lateral sclerosis (ALS) arise from several mechanisms including excitotoxicity, oxidative stress, immunologic or calcium dysregulation. Though the immunoglobulin mediated neuronal death has been...
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A Phage Display-Identified Peptide Selectively Binds to Kidney Injury Molecule-1 (KIM-1) and Detects KIM-1–Overexpressing Tumors In Vivo

Haque ME, Khan F, Chi L, Gurung S, Vadevoo SM, Park RW, Kim DK, Kim SK, Lee B

PURPOSE: This study was carried out to identify a peptide that selectively binds to kidney injury molecule-1 (KIM-1) by screening a phage-displayed peptide library and to use the peptide for...
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Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic study

Correa CR, Chen CY, Aldini G, Rasmussen , Ronchi CF, Berchieri-Ronchi C, Cho SM, Blumberg J, Yeum KJ

BACKGROUND/OBJECTIVES: Angelica keiskei is a green leafy vegetable rich in plant pigment phytochemicals such as flavonoids and carotenoids. This study examined bioavailability of flavonoids and carotenoids in Angelica keiskei and...
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Nobiletin attenuates neurotoxic mitochondrial calcium overload through K⁺ influx and ΔΨ(m) across mitochondrial inner membrane

Lee JH, Amarsanaa , Wu J, Jeon SC, Cui Y, Jung SC, Park DB, Kim SJ, Han SH, Kim HW, Rhyu IJ, Eun SY

Mitochondrial calcium overload is a crucial event in determining the fate of neuronal cell survival and death, implicated in pathogenesis of neurodegenerative diseases. One of the driving forces of calcium...
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Effects of glucosamine on Ca2+ signaling and K+ channel currents in T lymphocytes

Suh EY, Pang B, Kim SJ, Kim WK

  • KMID: 1458431
  • Korean J Med.
  • 2010 Nov;79(5):536-542.
BACKGROUND/AIMS: Glucosamine is widely taken as a functional food, and some studies reported its anti-inflammatory effects. K+ channels and intracellular signal play important roles in the activation of immune cells...
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Determination of angiotensin I-converting enzyme activity in equine blood: lack of agreement between methods of analysis

Costa MF, Carmona AK, Alves MF, Ryan TM, Davies HM, Anderson G, Slocombe R

Angiotensin-I converting enzyme (ACE) is a key regulator of blood pressure, electrolytes and fluid homeostasis through conversion of angiotensin I into angiotensin II. Recently, a genetic polymorphism of the ACE...
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Serum Chitotriosidase Activity in Pulmonary Tuberculosis: Response to Treatment and Correlations with Clinical Parameters

Cakir G, Gumus S, Ucar E, Kaya H, Tozkoparan E, Akgul EO, Karaman B, Deniz O, Kurt I, Ozkan M, Bilgic H

BACKGROUND: Chitotriosidase is an accepted marker of macrophage activation. In this study, we investigated serum chitotriosidase levels in pulmonary tuberculosis (PTB). METHODS: Forth-two patients with PTB and 30 healthy subjects were...
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Blocking Interleukin-4 Receptor α Using Polyethylene Glycol Functionalized Superparamagnetic Iron Oxide Nanocarriers to Inhibit Breast Cancer Cell Proliferation

Shaik AP, Shaik AS, Majwal AA, Faraj AA

PURPOSE: The specific targeting of interleukin-4 receptor α (IL4Rα) receptor offers a promising therapeutic approach for inhibition of tumor cell progression in breast cancer patients. In the current study, the...
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