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Discrepancy Between Ischemic Changes Observed on Non-Enhanced Computed Tomography and Perfusion Imaging: Implications for Decision-Making in Treatment

Broocks G, Fiehler J, Meyer L

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Ischemic Lesion Water Uptake in Acute Stroke: Is Blood Glucose Related to Cause and Effect?

Broocks G, Kemmling A, Aberle J, Kniep H, Bechstein , Flottmann , Leischner , Faizy TD, Nawabi J, Schön G, Sporns P, Thomalla G, Fiehler J, Hanning U

No abstract available.
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Venous Outflow Profiles Are Linked to Clinical Outcomes in Ischemic Stroke Patients with Extensive Baseline Infarct

Winkelmeier L, Broocks G, Kniep H, Geest V, Reinwald J, Meyer L, van Horn N, Guenego A, Zeleňák K, Albers GW, Lansberg M, Sporns P, Wintermark M, Fiehler J, Heit JJ, Faizy TD

Background and Purpose The benefit of endovascular thrombectomy (EVT) treatment is still unclear in stroke patients presenting with extensive baseline infarct. The use of additional imaging biomarkers could improve clinical...
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Simplified Assessment of Lesion Water Uptake for Identification of Patients within 4.5 Hours of Stroke Onset: An Analysis of the MissPerfeCT Study

Sporns PB, Höhne M, Meyer L, Krogias C, Puetz V, Thierfelder KM, Duering M, Kaiser D, Langner S, Brehm A, Rotkopf LT, Kunz WG, Fiehler J, Heindel W, Schramm P, Wiendl H, Minnerup H, Psychogios MN, Kemmling A, Minnerup J

Background and Purpose Many patients with stroke cannot receive intravenous thrombolysis because the time of symptom onset is unknown. We tested whether a simple method of computed tomography (CT)-based quantification...
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Bridging Thrombolysis versus Direct Mechanical Thrombectomy in Stroke Due to Basilar Artery Occlusion

Siow I, Y.Q. Tan B, Lee KS, Ong N, Toh E, Gopinathan A, Yang C, Bhogal P, Lam E, Spooner O, Meyer L, Fiehler J, Papanagiotou P, Kastrup A, Alexandrou M, Zubel S, Wu Q, Mpotsaris A, Maus V, Anderson T, Gontu V, Arnberg F, Lee TH, Chan BP, Seet RC, Teoh HL, Sharma VK, Yeo LL

Background and Purpose Mechanical thrombectomy (MT) is an effective treatment for patients with basilar artery occlusion (BAO) acute ischemic stroke. It remains unclear whether bridging intravenous thrombolysis (IVT) prior to...
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Cost-Effectiveness of Endovascular Thrombectomy in Childhood Stroke: An Analysis of the Save ChildS Study

Kunz WG, Sporns PB, Psychogios MN, Fiehler J, Chapot R, Dorn F, Grams A, Morotti A, Musolino P, Lee S, Kemmling A, Henkes H, Nikoubashman O, Wiesmann M, Jensen-Kondering U, Möhlenbruch M, Schlamann M, Marik W, Schob S, Wendl C, Turowski B, Götz F, Kaiser D, Dimitriadis K, Gersing A, Liebig T, Ricke J, Reidler P, Wildgruber M, Mönch S, for the Save ChildS Investigators

Background and Purpose The Save ChildS Study demonstrated that endovascular thrombectomy (EVT) is a safe treatment option for pediatric stroke patients with large vessel occlusions (LVOs) with high recanalization rates....
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Safety and Angiographic Efficacy of Intra-Arterial Fibrinolytics as Adjunct to Mechanical Thrombectomy: Results from the INFINITY Registry

Kaesmacher J, Abdullayev N, Maamari B, Dobrocky T, Vynckier J, Piechowiak EI, Pop R, Behme D, Sporns PB, Styczen H, Virtanen P, Meyer L, Meinel TR, Cantré D, Kabbasch C, Maus V, Pekkola J, Fischer S, Hasiu A, Schwarz A, Wildgruber M, Seiffge DJ, Langner S, Martinez-Majander N, Radbruch A, Schlamann M, Mihoc D, Beaujeux R, Strbian D, Fiehler J, Mordasini P, Gralla J, Fischer U

Background and Purpose Data on safety and efficacy of intra-arterial (IA) fibrinolytics as adjunct to mechanical thrombectomy (MT) are sparse. Methods INtra-arterial FIbriNolytics In ThrombectomY (INFINITY) is a retrospective multi-center observational...
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Mechanical Thrombectomy Versus Intravenous Thrombolysis in Distal Medium Vessel Acute Ischemic Stroke: A Multinational Multicenter Propensity Score-Matched Study

Salim HA, Yedavalli V, Musmar B, Adeeb N, Essibayi MA, Naamani KE, Henninger N, Sundararajan SH, Kühn AL, Khalife J, Ghozy S, Scarcia L, Tan BY, Pulli B, Heit JJ, Regenhardt RW, Cancelliere NM, Bernstock JD, Rouchaud A, Fiehler J, Sheth S, Puri AS, Dyzmann C, Colasurdo M, Barreau X, Renieri L, Filipe JP, Harker P, Radu RA, Marotta TR, Spears J, Ota T, Mowla A, Jabbour P, Biswas A, Clarençon F, Siegler JE, Nguyen TN, Varela R, Baker A, Altschul D, Gonzalez NR, Möhlenbruch MA, Costalat V, Gory B, Stracke CP, Aziz-Sultan MA, Hecker C, Shaikh H, Liebeskind DS, Pedicelli A, Alexandre AM, Tancredi I, Faizy TD, Kalsoum E, Lubicz B, Patel AB, Pereira VM, Guenego A, Dmytriw AA, the MAD MT Investigators

Background and Purpose The management of acute ischemic stroke (AIS) due to distal medium vessel occlusion (DMVO) remains uncertain, particularly in comparing the effectiveness of intravenous thrombolysis (IVT) plus mechanical...
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