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Leukostasis by hyperleukocytic childhood acute leukemia: pathophysiology, clinical presentation, and emergency care

Nam KL, Baek GY, Jeon IS

Hyperleukocytosis (HL), defined by a peripheral white blood cell (WBC) count exceeding 100,000/mm³, is occasionally observed in childhood acute leukemia. The increased viscosity in the micro-circulation by HL and the...
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Thick “Swiss Cheese” Appearance of Uterine Endometrium in Postmenopausal Women with Different Gynecologic Conditions

Ko Y, Chung J, Lee SR, Kim SH, Chae H, Kang BM

OBJECTIVES: To uncover gynecologic conditions with similar transvaginal sonographic findings of thick uterine endometrium with honeycomb appearance in pre-and postmenopausal women. METHODS: We retrospectively reviewed cases of patients with endometrial tissue...
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Peritoneal Fluid Cytology of Disseminated Large Cell Neuroendocrine Carcinoma Combined with Endometrioid Adenocarcinoma of the Endometrium

Lee YM, Yeo MK, Choi SY, Kim KH, Suh KS

No abstract available.
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A case of endometrial glassy cell carcinoma: a rare entity which necessitates of better understanding

Callegari , Algeri P, Buzzi A, Motta T, Manfredini C, Rota SM

Endometrial glassy cell carcinoma (EGCC) is a rare neoplasm, accounting for 0.5% of the carcinomas in the endometrium, composed of cells with granular eosinophilic or amphophilic cytoplasm, giving it a...
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Endometrial thickness cut-off value by transvaginal ultrasonography for screening of endometrial pathology in premenopausal and postmenopausal women

Park YR, Lee SW, Kim Y, Bae IY, Kim HK, Choe J, Kim YM

OBJECTIVE: To assess the clinical usefulness and diagnostic accuracy of ultrasonographic measurement of endometrial thickness (ET) in women with endometrial hyperplasia or cancer (EH+). METHODS: This retrospective cohort study included 29,995...
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Clinicopathologic features, treatment, prognosis and prognostic factors of neuroendocrine carcinoma of the endometrium: a retrospective analysis of 42 cases from the Kansai Clinical Oncology Group/Intergroup study in Japan

Matsumoto , Shimokawa , Nasu K, Shikama A, Shiozaki T, Futagami M, Kai K, Nagano H, Mori T, Yano M, Sugino N, Fujimoto E, Yoshioka N, Nakagawa S, Shimada M, Tokunaga H, Yamada Y, Tsuruta T, Tasaki K, Nishikawa , Kuji S, Motohashi , Ito K, Yamada T, Teramoto N

OBJECTIVE: We conducted a retrospective, multi-institutional, collaborative study to accumulate cases of neuroendocrine carcinoma of the endometrium, to clarify its clinicopathologic features, treatment, prognosis and prognostic factors to collate findings...
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Therapeutic efficacy of Mirena in gynecologic disease

Lee JY

The levonorgestrel-releasing intrauterine system (LNG-IUS) was originally developed as a method of contraception and was first marketed in Finland in 1990. In Korea, the only LNG-IUS approved for non-contraceptive use...
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The significance of sonographically thickened endometrium in asymptomatic postmenopausal women

Ozelci R, Dilbaz B, Akpınar F, Kınay T, Baser E, Aldemir O, Altınbas

OBJECTIVE: To investigate the correlation between sonographic, hysteroscopic, and pathological findings in postmenopausal asymptomatic patients with sonographically thickened endometrium. METHODS: The records of postmenopausal patients who attended the Menopause Outpatient Clinic...
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Combined estrogen-progestin pill is a safe and effective option for endometrial hyperplasia without atypia: a three-year single center experience

Wang Y, Nisenblat , Tao L, Zhang X, Li H, Ma C

OBJECTIVE: To evaluate the effectiveness of oral contraceptive pill (OCP) as therapy for endometrial hyperplasia (EH) without atypia in reproductive-aged women compared with oral progestin. METHODS: A retrospective cohort study was...
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Survival outcomes of adjuvant radiotherapy and chemotherapy in women with stage I serous papillary and clear cell carcinoma of the endometrium: a Korean multicenter study

Kim M, Kwon BS, Chang HK, Lee S, Chang SJ, Choi JY, Park SY, Lee M, Ryu HS, Kim YB

OBJECTIVE: To compare the survival outcomes of adjuvant radiotherapy and chemotherapy in women with uterine-confined endometrial cancer with uterine papillary serous carcinoma (UPSC) or clear cell carcinoma (CCC). METHODS: Medical records...
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Efficient Production of Murine Uterine Damage Model

Kim YY, Choi BB, Lim JW, Kim YJ, Kim SY, Ku SY

BACKGROUND: Thin or damaged endometrium causes uterine factor-derived infertility resulting in a failure of embryonic implantation. Regeneration of endometrium is a major issue in gynecology and reproductive medicine. Various types of cells...
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Six months response rate of combined oral medroxyprogesterone/levonorgestrel-intrauterine system for early-stage endometrial cancer in young women: a Korean Gynecologic-Oncology Group Study

Kim MK, Seong SJ, Kang SB, Bae DS, Kim JW, Nam JH, Lim MC, Lee TS, Kim S, Paek J

OBJECTIVE: To evaluate the efficacy of combined oral medroxyprogesterone acetate (MPA)/levonorgestrel-intrauterine system (LNG-IUS) treatment and to compare the diagnostic accuracy of endometrial aspiration biopsy with dilatation & curettage (D&C) in...
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Clear Cell Adenocarcinoma Originated from Adenomyosis

Park S, Cho A, Park CM

A 66-year-old postmenopausal woman received routine gynecologic check-up. Transvaginal ultrasonography and abdominal and pelvic computed tomography showed about 5-cm cystic mass in uterus with solid component and the patient had...
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Incidence of cervical, endometrial, and ovarian cancer in Korea during 1999–2015

Lim MC, Won YJ, Ko MJ, Kim M, Shim SH, Suh DH, Kim JW

OBJECTIVE: To investigate the incidence and trends of cervical (C53), endometrial (C54.1), and ovarian cancer (C56) among Korean females between 1999 and 2015. METHODS: The incidence of the three major gynecological...
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Clinicopathologic Characteristics and Causes of Postmenopausal Bleeding in Older Patients

Jo HC, Baek JC, Park JE, Park JK, Cho IA, Choi WJ, Sung JH

BACKGROUND: This study aimed to reveal the clinicopathologic features and causes of bleeding in older patients with postmenopausal bleeding (PMB) and to investigate the correlation between the ultrasonographic findings and...
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Bone marrow-derived stem cells contribute to regeneration of the endometrium

Lee YJ, Yi KW

Stem cells are undifferentiated cells capable of self-renewal and differentiation into various cell lineages. Stem cells are responsible for the development of organs and regeneration of damaged tissues. The highly...
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6-Shogaol reduces progression of experimental endometriosis in vivo and in vitro via regulation of VGEF and inhibition of COX-2 and PGE2-mediated inflammatory responses

Wang D, Jiang Y, Yang X, Wei Q, Wang H

Endometriosis (EM) is one of the most common gynaecological disorder affecting women in their reproductive age. Mechanisms involved in the pathogenesis of EM remains poorly understood, however inflammatory responses have...
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Predictive Value of Endometrial Thickness for Anemia in Adolescent Girls with Abnormal Uterine Bleeding

Lee JS, Cho YH, Jeon IS

BACKGROUND: Immaturity of the endocrine system that controls the normal menstrual cycle frequently results in abnormal uterine bleeding (AUB) and elicits anemia in adolescent girls. This study was conducted to...
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The effect of tamoxifen therapy on the endometrium and ovarian cyst formation in patients with breast cancer

Lee S, Kim YH, Kim SC, Joo JK, Seo DS, Kim KH, Lee KS

OBJECTIVE: To evaluate the effect of tamoxifen on female reproductive organs in women with breast cancer. METHODS: We retrospectively reviewed the medical records of 309 women with breast cancer who were...
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Multiple Synchronous Lesions in the Genital Tract of a Female: A Rare Combination with Unrelated Histogenesis

Jayalakshmy PS, Kulath FK, Parambil A, Sideeque N

Presenting a case of endometrioid adenocarcinoma of the endometrium, benign cystic teratoma of one ovary, fibrothecoma in the other ovary and adenomyosis in the uterus. Such a combination of synchronous...
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