- Expression and Packaging of a Human Endogenous Retrovirus-K Genomic DNA Clone
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Ha-Lee YM
- KMID: 2055032
- J Bacteriol Virol.
- 2006 Dec;36(4):237-245.
- doi: 10.4167/jbv.2006.36.4.237
Human contains large number of human endogenous retroviruses (HERVs) in its genome. One of the HERV families, HERV-K, entered human genome most recently and includes many members with full-length intact... -
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- Transposable Elements: No More 'Junk DNA'
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Kim YJ, Lee J, Han K
- KMID: 2053301
- Genomics Inform.
- 2012 Dec;10(4):226-233.
- doi: 10.5808/GI.2012.10.4.226
Since the advent of whole-genome sequencing, transposable elements (TEs), just thought to be 'junk' DNA, have been noticed because of their numerous copies in various eukaryotic genomes. Many studies about... -
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- Comparison of the age-related porcine endogenous retrovirus (PERV) expression using duplex RT-PCR
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Moon HJ, Kim HK, Park SJ, Lee CS, Song DS, Kang BK, Park BK
- KMID: 1726904
- J Vet Sci.
- 2009 Dec;10(4):317-322.
- doi: 10.4142/jvs.2009.10.4.317
Porcine endogenous retroviruses (PERVs) are members of family Retroviridae, genus Gamma retrovirus, and transmitted by both horizontally and vertically like other endogenous retroviruses (ERVs). PERV was initially described in the... -
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- Genomic Features of Retroelements and Implications for Human Disease
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Kim HS
- KMID: 2284672
- Genomics Inform.
- 2005 Dec;3(4):133-141.
Most of the endogenous retroviral genes integrated into the primate genome after the split of New World monkeys in the Oligocene era, approximately 33 million years ago. Because they can... -
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- No expression of porcine endogenous retrovirus after pig to monkey xenotransplantation
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Hwang S, Jung YD, Cho K, Ock SA, Oh KB, Kim HS, Yun IJ, Ahn C, Park JK, Im S
- KMID: 1707449
- Lab Anim Res.
- 2014 Jun;30(2):90-93.
- doi: 10.5625/lar.2014.30.2.90
This study was performed to investigate the expression of two porcine endogenous retrovirus (PERV) elements, PERV gag and full-length conserved PERV, in blood cells collected periodically from organ-recipient monkeys that... -
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- Regulation of porcine endogenous retrovirus by dual LTR1+2 (Long Terminal Region) miRNA in primary porcine kidney cells
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Chung HC, Nguyen VG, Moon HJ, Park YH, Park BK
- KMID: 2464096
- J Vet Sci.
- 2019 Sep;20(5):e50.
- doi: 10.4142/jvs.2019.20.e50
Porcine endogenous retroviruses (PERVs) integrate into germline DNA as proviral genome that enables vertical transmission from parents to their offspring. The provirus usually survives as part of the host genome... -
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- Analysis of env Subtypes of Porcine Endogenous Retrovirus in SNU Miniature Pigs
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Sa M, Park CG, Hwang ES
- KMID: 2135360
- J Bacteriol Virol.
- 2014 Mar;44(1):75-83.
- doi: 10.4167/jbv.2014.44.1.75
All xenografts from pigs impose infection risk by porcine endogenous retrovirus (PERV). The purpose of this study was to investigate the env constructs with the comparison of the ratio of... -
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- Characterization of Clones of Human Cell Line Infected with Porcine Endogenous Retrovirus (PERV) from Porcine Cell Line, PK-15
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Kim JH, Choi EY, Jung ES, Kwon Y, Lee DS, Hwang DY, Hwang ES
- KMID: 2170243
- Infect Chemother.
- 2009 Feb;41(1):1-8.
- doi: 10.3947/ic.2009.41.1.1
BACKGROUND: Porcine endogenous retroviruses (PERVs) form part of the chromosomes of all pigs. Since they can be produced as infectious virion and infect human cells, safety issues on PERVs infection... -
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- Construction of the Porcine Endogenous Retrovirus Envelope Glycoprotein A and B Specific Antibody
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Lee JE, Kim GW, Kim YB, Park HY
- KMID: 1474174
- J Bacteriol Virol.
- 2009 Jun;39(2):137-143.
- doi: 10.4167/jbv.2009.39.2.137
Xenotransplantation using porcine organs could potentially associate with the risk of pathogenic infections, because human tropic porcine endogenous retrovirus (PERV) particles could be released from pig cells or organs. While... -
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- Detection of Human Cytomegalovirus (HCMV) and Porcine Endogenous Retrovirus (PERV) with One Step Extraction Method
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Kim JH, Jung ES, Hwang ES
- KMID: 2170274
- Infect Chemother.
- 2010 Feb;42(1):12-16.
- doi: 10.3947/ic.2010.42.1.12
BACKGROUND: Xenotransplantation is thought to be one of the alternative methods to overcome the shortage of human organs for transplantation. Recipients should be immunosuppressed for graft survival, and thus, there... -
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- No Evidence of the Productive Replication of Porcine Endogenous Retrovirus (PERV) from SNU Miniature Pigs in Human Cell Line
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Kim JH, Jung ES, Park CG, Kim SJ, Hwang ES
- KMID: 2170306
- Infect Chemother.
- 2010 Jun;42(3):175-180.
- doi: 10.3947/ic.2010.42.3.175
BACKGROUND: The presence of porcine endogenous retrovirus (PERV) has been considered as one of the main hurdles to transplant pig's organs or tissues to human beings. There has been no... -
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- Analysis of swine leukocyte antigen class I gene profiles and porcine endogenous retrovirus viremia level in a transgenic porcine herd inbred for xenotransplantation research
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Matczyńska D, Sypniewski D, Gałka S, Sołtysik , Loch T, Nowak E, Smorąg Z, Bednarek I
- KMID: 2412129
- J Vet Sci.
- 2018 May;19(3):384-392.
- doi: 10.4142/jvs.2018.19.3.384
Molecular characterization of swine leukocyte antigen (SLA) genes is important for elucidating the immune responses between swine-donor and human-recipient in xenotransplantation. Examination of associations between alleles of SLA class I... -
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- Molecular Characterization of Porcine Endogenous Retrovirus gag Genes from Pigs in Korea
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Lee J, Lee D, Yoo JY, Kim GW, Park HY, Lee HT, Kim YB
- KMID: 2055026
- J Bacteriol Virol.
- 2006 Sep;36(3):185-194.
- doi: 10.4167/jbv.2006.36.3.185
Xenotransplantation, as a potential solution to the shortage of human organs, is associated with a number of concerns including immunologic rejection and xenogenic infection. While the pigs are considered the... -
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- Current Status and Future Perspectives of Xenotransplantation
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Park CG, Kim JS, Shin JS, Kim YH, Kim SJ
- KMID: 1819842
- J Korean Soc Transplant.
- 2009 Dec;23(3):203-213.
- doi: 10.4285/jkstn.2009.23.3.203
Xenotransplantation using pigs as the transplant source holds great promise to resolve the severe shortage of human organ donors. Although stem-cell-derived organ and tissue regeneration have a potential to solve... -
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