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A High Frequency of Lobectomy Instead of Total Thyroidectomy to Treat Medullary Thyroid Cancer in Korea: Data from the Korean National Health Insurance Service

Cho SW

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Reference Ranges of Serum Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Protein-3: Results from a Multicenter Study in Healthy Korean Adults

Jeong IK, Byun JK, Noh J, Kim SW, Chung YS, Park TS, Kim SW

Insulin-like growth factor-I (IGF-I) plays a pivotal role in the diagnosis and treatment of growth hormone (GH) excess or deficiency. The GH study group of the Korean Endocrine Society aims...
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Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea

You JH, Lee SA, Chun SY, Song SO, Lee BW, Kim DJ, Boyko EJ

Background: The aim of this study was to evaluate clinical outcomes in coronavirus disease 2019 (COVID-19) positive patients with type 2 diabetes compared to those without diabetes in Korea. Methods: We...
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Coordination of Multiple Cellular Processes by NR5A1/Nr5a1

Morohashi Ki, Inoue M, Baba T

The agenesis of the gonads and adrenal gland in revealed by knockout mouse studies strongly suggested a crucial role for Nr5a1 (SF-1 or Ad4BP) in organ development. In relation to...
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Efficacy and Safety of Pitavastatin in a Real-World Setting: Observational Study Evaluating SaFety in Patient Treated with Pitavastatin in Korea (PROOF Study)

Jeong IK, Kim SR

Background: While randomized controlled trials provide useful information about drug safety and efficacy, they do not always reflect the observed results in the real world. The prospective, observational, non-comparative trial...
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Association of Hyperparathyroidism and Papillary Thyroid Cancer: A Multicenter Retrospective Study

Jeong C, Kwon HI, Baek H, Kim HS, Lim DJ, Baek KH, Ha J, Kang MI

Background: Concomitant papillary thyroid cancer (PTC) and hyperparathyroidism (HPT) have been reported in several studies. Our study aimed to investigate the incidence of concomitant PTC in HPT patients upon preoperative...
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Transcriptome Analysis Identifies an Attenuated Local Immune Response in Invasive Nonfunctioning Pituitary Adenomas

Kim YH, Kim JH

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Changes in Glucose Metabolism after Adrenalectomy or Treatment with a Mineralocorticoid Receptor Antagonist for Primary Aldosteronism

Lin YF, Peng KY, Chang CH, Hu YH, Wu VC, Chung SD, Taiwan Primary Aldosteronism Investigation (TAIPAI) Study Group

Background: Data on the effects of excess aldosterone on glucose metabolism are inconsistent. This study compared the changes in glucose metabolism in patients with primary aldosteronism (PA) after adrenalectomy or...
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Percutaneous Adrenal Radiofrequency Ablation: A Short Review for Endocrinologists

Park BK

Image-guided radiofrequency ablation (RFA) has been accepted as a minimally invasive treatment for adrenal tumors in patients who are unable to undergo adrenalectomy. Accordingly, this treatment has become more readily...
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Trends in the Diagnosis and Treatment of Patients with Medullary Thyroid Carcinoma in Korea

Ahn HY, Chae JE, Moon H, Noh J, Park YJ, Kim SG

Background: Thyroid cancer is becoming increasingly common worldwide, but little is known about the epidemiology of medullary thyroid carcinoma (MTC). This study investigated the current status of the incidence and...
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The Association of Overt and Subclinical Hyperthyroidism with the Risk of Cardiovascular Events and Cardiovascular Mortality: Meta-Analysis and Systematic Review of Cohort Studies

Sohn SY, Lee E, Lee MK, Lee JH

Background: Whether hyperthyroidism is an independent risk factor for cardiovascular events remains controversial. We aimed to evaluate the association of overt and subclinical hyperthyroidism with the risk of ischemic heart...
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Clusterin Protects Lipotoxicity-Induced Apoptosis via Upregulation of Autophagy in Insulin-Secreting Cells

Hong SW, Lee J, Kim MJ, Moon SJ, Kwon H, Park SE, Rhee EJ, Lee WY

Background: There is a great need to discover factors that could protect pancreatic β-cells from apoptosis and thus prevent diabetes mellitus. Clusterin (CLU), a chaperone protein, plays an important role...
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Genetic and Environmental Factors Contributing to Visceral Adiposity in Asian Populations

Williams R, Periasamy M

Obesity-associated metabolic illnesses are increasing at an alarming rate in Asian countries. A common feature observed in the Asian population is a higher incidence of abdominal obesity—the “skinny-fat” Asian syndrome....
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Embryonic Development and Adult Regeneration of the Adrenal Gland

Kim JH, Choi MH

The adrenal gland plays a pivotal role in an organism’s health span by controlling the endocrine system. Decades of research on the adrenal gland have provided multiscale insights into the...
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Sarcopenia and Muscle Aging: A Brief Overview

Dao T, Green AE, Kim YA, Bae SJ, Ha KT, Gariani K, Lee Mr, Menzies KJ, Ryu D

The world is facing the new challenges of an aging population, and understanding the process of aging has therefore become one of the most important global concerns. Sarcopenia is a...
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Insulin Secretion and Insulin Resistance Trajectories over 1 Year after Kidney Transplantation: A Multicenter Prospective Cohort Study

Bang JB, Oh CK, Kim YS, Kim SH, Yu HC, Kim CD, Ju MK, So BJ, Lee SH, Han SY, Jung CW, Kim JK, Lee SH, Jeon JY

Background: We investigated the changing patterns of insulin secretion and resistance and risk factors contributing to the development of post-transplant diabetes mellitus (PTDM) in kidney recipients under tacrolimus-based immunosuppression regimen...
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Tumor Cells and Cancer-Associated Fibroblasts: A Synergistic Crosstalk to Promote Thyroid Cancer

Fozzatti L, Cheng Sy

Thyroid cancer is the most common endocrine malignancy. Although most thyroid cancer patients are successfully treated and have an excellent prognosis, a percentage of these patients will develop aggressive disease...
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In Vivo and In Vitro Quantification of Glucose Kinetics: From Bedside to Bench

Kim IY, Park S, Kim Y, Chang Y, Choi CS, Suh SH, Wolfe RR

Like other substrates, plasma glucose is in a dynamic state of constant turnover (i.e., rates of glucose appearance [Ra glucose] into and disappearance [Rd glucose] from the plasma) while staying...
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Minimally Invasive Adrenal Surgery

Kwak J, Lee KE

Since the introduction of minimally invasive surgery, laparoscopic adrenalectomy has become the main treatment option for adrenal masses. Various studies have reported that laparoscopic adrenalectomy showed fewer postoperative complications and...
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Updates in the Pathologic Classification of Thyroid Neoplasms: A Review of the World Health Organization Classification

Bai Y, Kakudo K, Jung CK

Advances in medical sciences and evidence-based medicine have led to momentous changes in classification and management of thyroid neoplasms. Much progress has been made toward avoiding overdiagnosis and overtreatment of...
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