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Ubiquitination of Aquaporin: in the kidney

Lee YJ, Kwon TH

Ubiquitination is known to be important for endocytosis and lysosomal degradation of aquaporin-2 (AQP2). Ubiquitin (Ub) is covalently attached to the lysine residue of the substrate proteins and activation and...
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Role of Pendrin in Acid: base Balance

Chang JH, Kim S

Pendrin (SLC26A4) is a Na+-independent Cl-/HCO3- exchanger which is expressed in the apical membranes of type B and non-A, non-B intercalated cells within the distal convoluted tubule, the connecting tubule,...
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Acquired Gitelman Syndrome

Kim YK, Song HC, Kim YS, Choi EJ

Acquired renal tubular disorder can be observed in various disease processes, especially autoimmune diseases. Gitelman syndrome is an autosomal recessive disease characterized by hypokalemic metabolic alkalosis, hypomagnesemia, and hypocalciuria. This...
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Expression of Rh Glycoproteins in the Mammalian Kidney

Han KH, Kim HY, Weiner D

Ammonia metabolism is a fundamental process in the maintenance of life in all living organisms. Recent studies have identified ammonia transporter family proteins in yeast (Mep), plants (Amt), and mammals...
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Renal Handling of Ammonium and Acid Base Regulation

Kim HY

Renal ammonium metabolism is the primary component of net acid excretion and thereby is critical for acid - base homeostasis. Briefly, ammonium is produced from glutamine in the proximal tubule...
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Comparison of Icodextrin and 2.5% Glucose in Potassium Metabolism by Acute K+oad via Dialysate in Continuous Ambulatory Peritoneal Dialysis Patients

Yi JH, Yun YW, Han SW, Kim HJ

This study aimed to compare the increment in plasma potassium concentration ([K+]) as well as the role of internal K+ balance for its changes following acute K+ supplementation between conventional...
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