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Mucosal dendritic cells shape mucosal immunity

Chang SY, Ko HJ, Kweon MN

Dendritic cells (DCs) are key modulators that shape the immune system. In mucosal tissues, DCs act as surveillance systems to sense infection and also function as professional antigen-presenting cells that...
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Expression of TNF-alpha and IL-1beta in Splenic Dendritic Cells and Their Serum Levels in Mouse Sparganosis

Yang HJ

Sparganosis is a tissue invading helminthiasis infecting intermediate hosts, including humans. Strong immune responses are expected to occur in early phases of infection. Thus, we investigated cytokine expressions in splenic...
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Active Immunization Using Dendritic Cells Mixed With Tumor Cells Inhibits The Growth Of Lymphomas

Park J, Suh C, Yang J, Park JS, Park KU, Min YJ, Kim HJ, Kim YH, Kim SH

Dendritic cells (DCs) are potent antigen-presenting cells for the induction and activation of cytotoxic T lymphocytes. We tested whether bone marrow derived DCs are capable of inducing protective immunity against...
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BCG-Induced Dendritic Cell Responses and Suppression of Interleukin-5 Production from T Cells in Atopic Asthmatics

Choi IS, Lin XH, Koh YA, Cui Y

Bacille Calmette-Guerin (BCG) induces potent Th1 responses with the help of interleukin (IL)-10 and IL-12 released from dendritic cells (DCs), and suppresses Th2- associated allergic reactions. However, there are still...
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Relationship between Dendritic Cells and Activated Eosinophils in Induced Sputum of Asthmatics

Koh YI, Lee JB, Lee SR, Ji SG, Choi IS

It has been suggested that dendritic cells (DCs) are critical antigen presenting cells for eosinophilic airway inflammation in a mouse model of asthma, and cysteinyl leukotrienes may play a role...
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Increased Expression of Intracellular HLA-DM but Not on the Surface of Blood Monocyte-derived Dendritic Cells During Maturation

Kang JM, Chung HG, Oh SJ, Song SY, Lee TH, Lee MG

Cutaneous dendritic cells (DCs), Langerhans cells (LCs) and dermal dendritic cells (DDCs), are present in an immature state. The maturation of DCs is crucial for initiating an immune response. Since...
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Identification of Pancreatic Cancer-Associated Tumor Antigen from HSP-Enriched Tumor Lysate-Pulsed Human Dendritic Cells

Kim HS, Kang D, Moon MH, Kim HJ

PURPOSE: Vaccine strategies utilizing dendritic cells (DCs) to elicit anti-tumor immunity are the subject of intense research. Although we have shown that DCs pulsed with heat-treated tumor lysate (HTL) induced...
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Strategies to Improve Dendritic Cell-based Immunotherapy against Cancer

Song SY, Kim HS

Dendritic cells (DCs) play a pivotal role in T cell-mediated immunity and have been shown to induce strong antitumor immune responses in vitro and in vivo. Various approaches utilizing different...
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