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Testosterone and Dehydroepiandrosterone Treatment in Ageing Men: Are We All Set?

Walther A, Seuffert J

Although demographic statistics show that populations around the world are rapidly ageing, this rising life expectancy is accompanied by an increase in the number of people living with age-related chronic...
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The association between serum dehydroepiandrosterone sulfate (DHEAS) levels and job-related stress among female nurses

Cho S, Park WJ, Kang W, Lim HM, Ahn JS, Lim DY, Moon JD

BACKGROUND: Dehydroepiandrosterone sulfate (DHEAS) is an endogenous steroid hormone produced by the adrenal gland. DHEAS has been suggested to play a protective role against psychosocial stress. The aim of this...
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Dehydroepiandrosterone and Erectile Function: A Review

El-Sakka A

To review the contemporary knowledge regarding the dehydroepiandrosterone and erectile function. Medline was reviewed for English-language journal articles spanning the time between January 1990 and December 2017, using the terms...
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Association between Body Mass Index and Serum Dehydroepiandrosterone Sulfate Level in 8-Year-Old Girls

Na JH, Kim YH, Hong SJ, Kim JK

BACKGROUND: Adiposity may play a role as a potential trigger for adrenarche. The purpose of this study was to evaluate the association between body mass index (BMI) and serum dehydroepiandrosterone...
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Dehydroepiandrosterone Sulfate Level Varies Nonlinearly with Symptom Severity in Major Depressive Disorder

Uh D, Jeong HG, Choi KY, Oh SY, Lee S, Kim SH, Joe SH

OBJECTIVE: The pathophysiology of major depressive disorder (MDD) is still not well understood. Conflicting results for surrogate biomarkers in MDD have been reported, which might be a consequence of the...
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Dehydroepiandrosterone and cortisol concentrations in the cerebrospinal fluid of dogs

Mongillo P, Bernardini M, Prana E, Balducci F, Gabai G, Marinelli

Concentrations of cortisol, dehydroepiandrosterone and dehydroepiandrosterone-sulfate were measured by performing radioimmunoassay of the cerebrospinal fluid of 68 dogs diagnosed with idiopathic epilepsy or inflammatory, degenerative, or non-neurological disease. No steroid...
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The Association between Dehydroepiandrosterone Sulfate (DHEA-S) and Bone Mineral Density in Korean Men and Women

Park SG, Hwang S, Kim JS, Park KC, Kwon Y, Kim KC

BACKGROUND: The relationship between dehydroepiandrosterone sulfate (DHEA-S) and bone mineral density (BMD) is controversial. And findings of most studies that have investigated this relationship are restricted to postmenopausal women. In...
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The Relationship between Opioids Use, Cortisol and DHEAS

Jung JH, Choi YS, Kim SM, Lee JY, Kim EH, Kim JE, Kim EY, Park HJ, Yoon DJ

PURPOSE: Fatigue, energy loss, feeling of helplessness, poor appetite, pain besides general weakness are major symptoms presented to terminally ill cancer patients. These symptoms are similar to those that appeared...
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The Effect of Dehydroepiandrosterone on Isoproterenol-induced Cardiomyopathy in Rats

Jeong JH, Kim CW, Yim SH, Shin YK, Park KW, Park ES

  • KMID: 2071624
  • Korean J Physiol Pharmacol.
  • 2006 Apr;10(2):79-83.
We evaluated therapeutic and preventive properties of dehydroepiandrosterone (DHEA), a weak androgenic steroid, against isoproterenol-induced cardiomyopathy. The cardiomyopathy was induced by daily i.p. administration of isoproterenol to rats for five...
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Preventive Effect of Combined Administration of BCG and DHEA against Development of Asthma

  • KMID: 2299653
  • Korean J Asthma Allergy Clin Immunol.
  • 2005 Dec;25(4):291-298.
BACKGROUND: Both Bacille Calmette-Guerin (BCG) vaccine and dehydroepiandrosterone (DHEA) have a suppressive effect on asthma. OBJECTIVE: To evaluate the effect of BCG and DHEA combination against the development of asthma. METHOD:...
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Effects of Vitamin E and Dehydroepiandrosterone on The Formation of Preneoplastic Lesions in Rat Hepatocellular Carcinogenesis

Kim S, Choi H

  • KMID: 2269840
  • Korean J Nutr.
  • 2005 Jun;38(5):364-372.
This study is designed to examine the effects of dietary supplementation with vitamin E and dehydroepiandrosterone (DHEA) on the formation of preneoplastic lesions in diethylnitrosamine (DEN) induced rat hepatocarcinogenesis. All...
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Effect of DHEA Administration on PUFA/SFA Ratio and Lipid Peroxide in Rat Liver Microsome

Kwak CS, Kim MY

  • KMID: 2257565
  • Korean J Nutr.
  • 2005 May;38(4):297-306.
It is known that dehydroepiandrosterone (DHEA) shows a dual effect, prooxidant or antioxidant, depending on the dosage or physiological status of animals. The purpose of this study was to determine...
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cDNA Array Analysis of Genes Expressed in the Rat Polycystic Ovary Induced by Dehydroepiandrosterone

Jeong CH, Kim HC, Kang SG, Kim JR

  • KMID: 2272403
  • Korean J Obstet Gynecol.
  • 2004 Oct;47(10):1931-1939.
OBJECTIVE: Polycystic Ovarian Syndrome (PCOS) is the most common endocrine disorder. Chronic anovulation, hyperandrogenism, hirsutism, obesity, infertility and polycystic ovaries (PCO) are clinical hallmarks of PCOS. PCO can be induced...
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Suppressive effect of dehydroepiandrosterone on the development of asthmatic reaction in BALB/c mice

Cui Y, Choi IS, Koh YI, Koh YA, Lee HC

  • KMID: 2285824
  • J Asthma Allergy Clin Immunol.
  • 2004 Mar;24(1):116-126.
BACKGROUND: Dehydroepiandrosterone (DHEA), an adrenal androgen, may regulate Th1/Th2 cytokines. OBJECTIVE: To determine whether DHEA have a preventive effect against the development of asthma, a Th2-associated disease. MATERIALS AND METHODS: Female BALB/c...
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Effect of DHEA on airway hyperresponsiveness and inflammation in murine model of asthma

Jang AS

  • KMID: 2285818
  • J Asthma Allergy Clin Immunol.
  • 2004 Mar;24(1):75-76.
No abstract available.
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Effect of Dehydroepiandrosterone Sulfate on Cardiovascular Risk Factors

Kim YJ, Park NC, Kim YJ, Lee SY, Choi SH, Min HG

  • KMID: 2227031
  • Korean J Androl.
  • 2003 Dec;21(3):158-163.
PURPOSE: Morbidity and mortality from cardiovascular disease have increased in Korea. Some studies have suggested that dehydroepiandrosterone sulfate(DHEAS) may play an important role in the pathogenesis or prevention of cardiovascular...
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Effect of DHEA Administration before, during and after Dexamethasone Treatment on Body Weight and Mass of TypeI, II Muscles in Rats

Choe MA, Shin GS, An GJ, Lee EJ

  • KMID: 2296844
  • J Korean Acad Nurs.
  • 2002 Oct;32(5):727-734.
PURPOSE: This study was to determine the effect of DHEA administration before, during, and after dexamethasone treatment on body weight and TypeI,II muscle weight of rat receiving dexamethasone treatment. METHOD: Wistar...
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The Relationship between Dehydroepiandrosterone sulfate and Insulin Resistance Syndrome in Women

Kim HJ, Hong ES, Oh JY, Hong YS, Sung YA

  • KMID: 2200047
  • J Korean Soc Endocrinol.
  • 2002 Oct;17(5):675-684.
BACKGROUND: Dehydroepiandrosterone (DHEA) is an androgen precursor, and is known to be decreased by the aging process. DHEA has been known to have a protective effect on insulin resistance and...
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The Effect of Dehydroepiandrosterone on Expression of Elastin in Cultured Skin Fibroblasts

Kim CD, Ryoo YW, Lee KS

  • KMID: 2250813
  • Korean J Dermatol.
  • 2002 Jun;40(6):599-606.
BACKGROUND: Dehydroepiandrosterone(DHEA) and its sulfate ester dehydro- epiandrosterone sulfate(DHEA-S) are the steroids secreted most abdundantly by the human adrenal gland, but the physiologic role remains uncertain. Elastin is one of...
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Dehydroepiandrosterone sulphate (DHEAS) levels in premenopausal women with systemic lupus erythematosus

Yun JH, Ryu SH, Jung WT, Lee SW, An WS, Lee H, Son CH, Kim SE, Kim DG, Chung WT

  • KMID: 1598554
  • J Korean Rheum Assoc.
  • 2002 Jun;9(2):90-96.
OBJECTIVE: Dehydroepiandrosterone sulphate (DHEAS), the major steroidal product of the human adrenal, is abnormally low in patients with SLE. Moreover, a recent study confirms a positive effect of the precursor...
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