- Thiol-actwated Cytolysins from Gram-positive Bacteria as a Possible New Bacterial Modulim : Implication in the Immune Response 35
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Mitsuyama
- KMID: 2099331
- J Korean Soc Microbiol.
- 2000 Oct;35(5):327-329.
No Abstract Available. -
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- Target Therapy for Colorectal Cancer
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Lee KH
- KMID: 2049770
- Yeungnam Univ J Med.
- 2006 Dec;23(2):143-151.
- doi: 10.12701/yujm.2006.23.2.143
In the past decade, the median duration of survival among patients with advanced colorectal cancer has increased from 12 months to about 18 months, primarily as a results of the... -
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- 11 Cases of Aspergillosis
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Hwang HW, Sohn JS, Suh CH
- KMID: 1724102
- Korean J Pathol.
- 1985 Sep;19(3):325-331.
Genus of aspergilli are ubiquitous saprophytic molds in nature, which are recognized about 700 species, at least eight are pathologic for human. Pulmonary aspergillosis is rare disease, most frequent presenting... -
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- Recent treatment of pancreatic cancer
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Kim JW
- KMID: 2305777
- Korean J Med.
- 2009 Dec;77(6):695-702.
Pancreatic cancer has a high mortality rate and short survival as a result of the high incidence of metastatic disease at diagnosis, the fatal clinical course, and the lack of... -
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- A Case of Autoimmune Sensorineural Hearing Loss Responding to Cytotoxic Agent
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Lee YW, Lee J, Kim MB, Chang SO
- KMID: 2457195
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2019 Aug;62(8):470-474.
- doi: 10.3342/kjorl-hns.2018.00549
Autoimmune sensorineural hearing loss is a rare disease characterized by bilateral sensorineural hearing loss, some in a progressive pattern and others in idiopathic or fluctuating pattern, often accompanied by vestibular... -
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- Close Encounter of V. vulnificus with Host Cells is a Prerequisite to the Cytotoxicity of yet Unidentified New Virulence Factor
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Kim YR, Kim CM, Rhee JH
- KMID: 1615421
- J Bacteriol Virol.
- 2003 Mar;33(1):19-26.
Live Vibrio vulnificus is highly cytotoxic to host cells in vivo and in vitro. The two most representative cytotoxins, cytolytic hemolysin and elastolytic protease, have been regarded to play major... -
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- A Case of Cutaneous Plasmacytoma Treated with Thalidomide
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Hwang ES, Son SW, Kim IH
- KMID: 2302798
- Korean J Dermatol.
- 2004 Oct;42(10):1325-1328.
Cutaneous involvement has been reported in all types of malignant plasma cell disorders including multiple myeloma, solitary myeloma of bone, plasma cell leukemia, and extramedullary plasmacytoma. But metastatic plasmacytomas in... -
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- Tumor hypoxia and reoxygenation: the yin and yang for radiotherapy
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Hong BJ, Kim J, Jeong H, Bok S, Kim YE, Ahn GO
- KMID: 2366044
- Radiat Oncol J.
- 2016 Dec;34(4):239-249.
- doi: 10.3857/roj.2016.02012
Tumor hypoxia, a common feature occurring in nearly all human solid tumors is a major contributing factor for failures of anticancer therapies. Because ionizing radiation depends heavily on the presence... -
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- A Case of Prolonged Hypogammaglobulinemia after Rituximab-Containing Chemotherapy in a Patient with Lymphoma
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Noh HJ, Gong BH, Kim YS, Jung YH, Woo IS, Han CW
- KMID: 2269250
- Korean J Med.
- 2014 Sep;87(3):357-362.
- doi: 10.3904/kjm.2014.87.3.357
Rituximab, an anti-CD20 monoclonal antibody, is an effective target agent against the B lymphocytes in B-cell lymphoid malignancies and various lymphoproliferative diseases. Moreover, the toxicity of rituximab is less severe... -
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- Induction of Apoptosis with Moringa oleifera Fruits in HCT116 Human Colon Cancer Cells Via Intrinsic Pathway
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Guon TE, Chung HS
- KMID: 2401572
- Nat Prod Sci.
- 2017 Dec;23(4):227-234.
- doi: 10.20307/nps.2017.23.4.227
Moringa oleifera Lam (M. oleifera, Moringaceae) is a tree of the Moringaceae family that can reach a height of between 5 and 10 m. The current paper presents cytotoxic effect... -
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- New Systemic Treatment for Malignant Melanoma
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Lee SJ, Chae YS
- KMID: 2267785
- Korean J Med.
- 2013 Oct;85(4):357-363.
Although early stage melanoma can be cured by complete resection, the prognosis of the patients with unresectable or metastatic disease is dismal with the overall survival less than 1 year... -
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- Cytotoxic Activity and Three-Dimensional Quantitative Structure Activity Relationship of 2-Aryl-1,8-naphthyridin-4-ones
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Kim YJ, Kim EA, Chung ML, Im C
- KMID: 2285389
- Korean J Physiol Pharmacol.
- 2009 Dec;13(6):511-516.
- doi: 10.4196/kjpp.2009.13.6.511
A series of substituted 2-arylnaphthyridin-4-one analogues, which were previously synthesized in our laboratory, were evaluated for their in vitro cytotoxic activity against human lung cancer A549 and human renal cancer... -
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- Antibody-Drug Conjugates in Head and Neck Cancer
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Kim JW
- KMID: 2386370
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2017 Jul;60(7):331-335.
- doi: 10.3342/kjorl-hns.2017.00031
Antibody-drug conjugates (ADCs) represent a promising therapeutic treatment for cancer patients by combining the antigen-targeting specificity of monoclonal antibodies (mAbs) with the cytotoxic potency of chemotherapeutic drugs. ADCs consist of... -
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- Co-expression of CdtA and CdtC subunits of cytolethal distending toxin from Aggregatibacter actinomycetemcomitans
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Lee SJ, Lee KY, Kim HS
- KMID: 2321649
- J Korean Acad Periodontol.
- 2009 Aug;39(Suppl):231-237.
PURPOSE: Cytolethal distending toxin (CDT) is a family of heat-labile cytotoxins produced by several gram-negative mucosa-associated pathogens, including Aggregatibacter actinomycetemcomitans. CDT is well known to be capable of inducing growth... -
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- A Case of Nonspecific Interstitial Pneumonitis Improved After Cyclosporin Therapy
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Ahn SM, Jo SK, Lim SK, Song YJ, Choi JH, Sheen SS, Oh YJ, Choi YH, Park KJ, Hwang SC
- KMID: 2318459
- Tuberc Respir Dis.
- 2003 Dec;55(6):631-635.
Idiopathic interstitial pneumonia is a group of lung disease classified by clinical, radiological and pathologic findings. Steroid is described in many reports as an effective treatment for the idiopathic interstitial... -
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- Imatinib-Mesylate Induced Interstitial Pneumonitis in Two CML Patients
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Kim TH, Kim BG, Cho SW, Cho SK, Kim HJ, Yuh YJ, Kim SR
- KMID: 2319555
- Tuberc Respir Dis.
- 2011 Sep;71(3):210-215.
Imatinib mesylate, a selective inhibitor of BCR-ABL kinase activity, has demonstrated significant clinical efficacy in the treatment of chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). It has become... -
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- A Clinical Observation on Lupus Nephritis in Children
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Ahn KM, Ko JS, Park HW, Ha IS, Cheong HI, Choi Y, Kim HJ
- KMID: 2142456
- J Korean Pediatr Soc.
- 1994 Jun;37(6):842-849.
We reviewed the clinical features, histrologic patterns and clinical courses of 30 children with lupus nephritis retrospectively, and the results were summerized as follows; 1) The male to female ratio... -
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- A case of interstitial lung diseasec caused by Rituximab in non-Hodgkin lymphoma
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Choi YJ, Jung WJ, Oh SI, Jeon MH, Sohn HJ, Han EM, Suh C
- KMID: 2256603
- Korean J Med.
- 2006 Oct;71(4):449-455.
Rituximab targets CD20+ B cells and has been used increasingly for the treatment of B-cell Non-Hodgkin Lymphoma, alone or in combination with cytotoxic agents. Rituximab can kill CD20+cells by multiple... -
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- The Role of Reactive Oxygen Species in Regulating T Cell-mediated Immunity and Disease
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Yarosz EL, Chang CH
- KMID: 2404896
- Immune Netw.
- 2018 Feb;18(1):e14.
- doi: 10.4110/in.2018.18.e14
T lymphocytes rely on several metabolic processes to produce the high amounts of energy and metabolites needed to drive clonal expansion and the development of effector functions. However, many of... -
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- Anticancer Activity of Cobra Venom Polypeptide, Cytotoxin-II, against Human Breast Adenocarcinoma Cell Line (MCF-7) via the Induction of Apoptosis
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Ebrahim K, Shirazi FH, Vatanpour , zare A, Kobarfard , Rabiei H
- KMID: 2176121
- J Breast Cancer.
- 2014 Dec;17(4):314-322.
- doi: 10.4048/jbc.2014.17.4.314
PURPOSE: Breast cancer is a significant health problem worldwide, accounting for a quarter of all cancer diagnoses in women. Current strategies for breast cancer treatment are not fully effective, and... -
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