- Expression of Cyclin B1 and cdc2 in Nodal Non-Hodgkin's Lymphoma and its Prognostic Implications
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Jin YH, Park CK
- KMID: 1101545
- J Korean Med Sci.
- 2002 Jun;17(3):322-327.
- doi: 10.3346/jkms.2002.17.3.322
To investigate the role of cyclin B1 and cdc2 in the pathogenesis and progression of malignant lymphoma, 68 cases of nodal non-Hodgkin's lymphoma were examined about the expression of cyclin... -
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- Expression of Cyclin A, B1, D1, D3, and E in Non-Small Lung Cancers
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Ha SY, Kim HK, Im JS, Cho HY, Chung DH, An J
- KMID: 2199874
- J Lung Cancer.
- 2012 Jun;11(1):33-37.
- doi: 10.6058/jlc.2012.11.1.33
PURPOSE: Cyclins, and their associated cyclin dependent kinases, regulate progression of the cell cycle through the G1 phase and into the S-phase during the DNA replication process. Cyclin E regulation... -
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- Cyclin B1 and D1 expression in invasive cervical cancer
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Kim YT, Zhao M, Kim HY, Kang MH, Kim JW, Kim SH, Kim JH, Kim SW, Yoon BS
- KMID: 1575056
- Korean J Gynecol Oncol.
- 2005 Sep;16(3):256-263.
OBJECTIVE: Cyclin is a family of regulatory proteins that play a key role in controlling the cell cycle. Abnormalities of cell cycle regulators, including cyclins and cyclin dependent kinases (CDKs),... -
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- Relationship between the expression of cyclin B1, D1 and the various prognostic factors in ovarian carcinoma
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Kim HY, Kim JW, Kim YT, Kang MH, Kim JH, Kim SH, Kim SW, Yoon BS
- KMID: 2272740
- Korean J Obstet Gynecol.
- 2005 Nov;48(11):2670-2681.
OBJECTIVE: The objective of this study was to evaluate the relationship between the expression of cyclin B1, D1 and the various prognostic factors in ovarian carcinoma. METHODS: In this study, fresh... -
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- The Influence of Expressions of Cyclin B1 and D1 on Clinicopathologic Prognostic Factors and Survival Rate in Gastric Cancer
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Kang GC, Park US, Park YG, Chi KC, Lee JH, Chang IT, Park SI
- KMID: 1844194
- J Korean Surg Soc.
- 2004 Jul;67(1):25-30.
PURPOSE: Disturbance in normal cell cycles by cell cycle control factors is an important process of cancer carcinogenesis. The aims of this dissertation were identify the influence of cyclin B1... -
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- Prognostic Significance of Cyclin B1 and p53 Expression in Patient with Esophageal Squamous Cell Carcinoma
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Kim CH, Jo BG, Cho SR, Chun BK
- KMID: 2010960
- Korean J Thorac Cardiovasc Surg.
- 2003 Dec;36(12):952-960.
BACKGROUND: It has been reported that p53 regulates the G2-M checkpoint transition through cyclin B1, and it has been suggested that p53 plays an important role in the development and... -
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- Expression of Anaphase Promoting Complex (APC) and APC Regulatory Proteins in Invasive Ductal Carcinoma Associated with Paget's Disease
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Park KH, Yi SY, Yang WI, Kang Y, Lee KG
- KMID: 2073843
- Korean J Pathol.
- 2004 Oct;38(5):319-323.
BACKGROUND: Oncogene expression in Paget's disease of the breast is not well known. To characterize invasive ductal carcinoma associated with Paget's disease, we studied expression of anaphase promoting complex (APC)... -
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- Expression of Cyclins (D1, A, E, and B1) in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced Rat Bladder Carcinogenesis
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Kwon GY, Park ES, Bong SG, Lee TJ, Kim MK, Yoo JH, Song KY
- KMID: 2011752
- Korean J Pathol.
- 2003 Aug;37(4):255-262.
BACKGROUND: Cell cycle deregulation plays a major role in chemical multistage carcinogenesis.Therefore, the evaluation of cell cycle proteins is important. METHODS: In order to induce carcinogenesis in the rat urinary... -
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- Overexpressions of Cyclin B1, cdc2, p16 and p53 in Human Breast Cancer: The Clinicopathologic Correlations and Prognostic Implications
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Chae SW, Sohn JH, Kim DH, Choi YJ, Park YL, Kim K, Cho YH, Pyo JS, Kim JH
- KMID: 1777016
- Yonsei Med J.
- 2011 May;52(3):445-453.
- doi: 10.3349/ymj.2011.52.3.445
PURPOSE: The molecular mechanisms that are responsible for the initiation and progression of breast cancers are largely unknown. This study was to analyze the cyclin B1, cdc2, p53 and p16... -
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- The Expression of Hypoxia Inducible Factor-1alpha and Its Correlation with the Expressions of Cyclin A1 and Cyclin B1 and the Clinicopathologic Factors of Uterine Cervical Carcinoma
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Pyo JY, Cho JH, Kim H, Park JP, Kim YT, Cho NH
- KMID: 1472549
- Korean J Pathol.
- 2009 Feb;43(1):13-19.
- doi: 10.4132/KoreanJPathol.2009.43.1.13
BACKGROUND: Hypoxia inducible factor-1alpha(HIF-1alpha) is a transcription factor for various target genes that are involved in adapting cells to hypoxia. It promotes cell proliferation and survival via modulation of such... -
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- Cellular Effects of Troglitazone on YD15 Tongue Carcinoma Cells
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Ta Thi L, Yoo H
- KMID: 2354198
- Int J Oral Biol.
- 2016 Sep;41(3):113-118.
- doi: 10.11620/IJOB.2016.41.3.113
An FDA approved drug for the treatment of type II diabetes, Troglitazone (TRO), a peroxisome proliferator–activated receptor gamma agonist, is withdrawn due to severe idiosyncratic hepatotoxicity. In the search for... -
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- Effect of Phospholipase C-gamma1 Overexpression on the Protein Level of Waf1, PCNA, and Cyclin B1 Following Ultraviolet C Irradiation
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Shin SY, Lee YH, Baek SH, Kim SY, Kim JR, Kim JH
- KMID: 1804434
- Cancer Res Treat.
- 2001 Oct;33(5):427-432.
PURPOSE: It has been demonstrated that PLC-gamma1 is overexpressed in many tumor cells, and that overexpression of Phospholipase C (PLC)-gamma1 is associated with tumor progression. In order to understand the... -
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- Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma
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Moon SJ, Kim JH, Kong SH, Shin CS
- KMID: 2471729
- Endocrinol Metab.
- 2020 Mar;35(1):132-141.
- doi: 10.3803/EnM.2020.35.1.132
BACKGROUND: Adrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been... -
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- Indole-3-carbinol and genistein inhibit growth of human uterine leiomyoma cells
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Jeong HW, Kim YO, Shin SJ, Kwon SH, Cha SD, Cho CH
- KMID: 2077761
- Korean J Obstet Gynecol.
- 2007 Jun;50(6):880-886.
OBJECTIVE: To determine whether Indole-3-carbinol (I3C) can enhance the inhibitory effect of genistein on a human uterine leiomyoma cells. METHODS: Five uterine leiomyoma tissues were obtained from hysterectomies conducted on... -
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- Treatment with sodium butyrate and rapamycin inhibit growth of human cervical cancer cells
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Jeon YJ, Cho CH, Shin SJ, Kwon SH, Cha SD
- KMID: 2244544
- Korean J Gynecol Oncol.
- 2007 Sep;18(3):165-171.
OBJECTIVE: To evaluate whether mTOR inhibition by rapamycin can enhance the inhibitory effect of sodium butyrate, a histone deacetylase (HDAC) inhibitor on human cervical cancer cell line HeLa. METHODS: Cervical... -
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- Ethanol Elicits Inhibitory Effect on the Growth and Proliferation of Tongue Carcinoma Cells by Inducing Cell Cycle Arrest
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Le TD, Do TA, Yu R, Yoo H
- KMID: 1768004
- Korean J Physiol Pharmacol.
- 2012 Jun;16(3):153-158.
- doi: 10.4196/kjpp.2012.16.3.153
Cellular effects of ethanol in YD-15 tongue carcinoma cells were assessed by MTT assay, caspase activity assay, Western blotting and flow cytometry. Ethanol inhibited the growth and proliferation of YD-15... -
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- Sunitinib Malate Synergistically Potentiates Anti-Tumor Effect of Gemcitabine in Human Bladder Cancer Cells
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Yoon CY, Lee JS, Kim BS, Jeong SJ, Hong SK, Byun SS, Lee SE
- KMID: 2315651
- Korean J Urol.
- 2011 Jan;52(1):55-63.
PURPOSE: Sunitinib malate (Sutent; Pfizer, New York, NY, USA) is a highly selective multi-targeted agent and has been reported to have potent anti-tumor effects against various tumors, including renal cell... -
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- Propofol-induced Immediate Early Gene Expression in Human Neuroblastoma Cell Lines
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Kim DI, Kim JR, Kim SY
- KMID: 2244022
- Korean J Anesthesiol.
- 2008 Feb;54(2):189-196.
- doi: 10.4097/kjae.2008.54.2.189
BACKGROUND: General anesthetics were known to induce expression of immediate early genes (IEGs), including c-fos and c-jun. However, mechanisms of IEG induction by general anesthetics were not fully understood. METHODS: IEG... -
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- Augmentation of Sodium Butyrate-induced Apoptosis by Phosphatidylinositol 3-kinase Inhibition in the Human Cervical Cancer Cell-line
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Park JK, Cho CH, Ramachandran S, Shin SJ, Kwon SH, Kwon SY, Cha SD
- KMID: 2270824
- Cancer Res Treat.
- 2006 Apr;38(2):112-117.
PURPOSE: Sodium butyrate (NaBT) is principally a histone deacetylase (HDAC) inhibitor, and it has the potential to arrest HPV-positive carcinoma cells at the G1 to S phase transition of the... -
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- Helicobacter pylori inhibited cell proliferation in human periodontal ligament fibroblasts through the Cdc25C/CDK1/cyclinB1 signaling cascade
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Li H, Liang D, Hu N, Dai X, He J, Zhuang H, Zhao W
- KMID: 2454084
- J Periodontal Implant Sci.
- 2019 Jun;49(3):138-147.
- doi: 10.5051/jpis.2019.49.3.138
PURPOSE: Several studies have shown that the oral cavity is a secondary location for Helicobacter pylori colonization and that H. pylori is associated with the severity of periodontitis. This study... -
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