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Status of group B streptococcal vaccine development

Lin SM, Zhi Y, Ahn KB, Lim S, Seo HS

Streptococcus agalactiae (group B streptococcus, GBS) is a leading causal organism of neonatal invasive diseases and severe infections in the elderly. Despite significant advances in the diagnosis and treatment of...
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Efficacy of inactivated variant porcine epidemic diarrhea virus vaccines in growing pigs

Lee SH, Yang DK, Kim HH, Cho IS

PURPOSE: The first aim of this study was to develop a novel inactivated porcine epidemic diarrhea virus (PEDV) vaccine using the recently isolated Korean PEDV QIAP1401 strain and to evaluate...
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Distinct features of dendritic cell-based immunotherapy as cancer vaccines

Lee C, Lee M, Rhee I

Dendritic cells (DCs) are the most professional antigen presenting cells that play important roles in connection between innate and adaptive immune responses. Numerous studies revealed that the functions of DCs...
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Calcium-dependent protein kinases are potential targets for Toxoplasma gondii vaccine

Foroutan M, Ghaffarifar F

Toxoplasma gondii belongs to the Apicomplexa phylum that caused a widespread zoonotic infection in wide range of intermediate hosts. Over one-third of the world's population are latently infected with T....
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Anti-infective potential of catechins and their derivatives against viral hepatitis

Song JM

Polyphenols including catechins from green tea (Camellia sinensis) have been reported to have anti-infective activities against a broad spectrum of viruses and other pathogens. During the last two decades, antiviral...
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Epidemiology of severe fever and thrombocytopenia syndrome virus infection and the need for therapeutics for the prevention

Robles NJ, Han HJ, Park SJ, Choi YK

Over the past ten years there has been a marked increase in cases of severe fever and thrombocytopenia syndrome in East Asia. This tick-borne hemorrhagic fever presents along with clinical...
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Challenges of influenza A viruses in humans and animals and current animal vaccines as an effective control measure

Yoo SJ, Kwon T, Lyoo YS

Influenza A viruses (IAVs) are genetically diverse and variable pathogens that share various hosts including human, swine, and domestic poultry. Interspecies and intercontinental viral spreads make the ecology of IAV...
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Evaluation of two different enzyme-linked immunosorbent assay for severe fever with thrombocytopenia syndrome virus diagnosis

Yu MA, Jeong HW, Park SJ, Kim YI, Kwon HI, Kim EH, Si YJ, Yu KM, Robles NJ, Han HJ, Choi YK

To develop the large scale serological assay for severe fever with thrombocytopenia syndrome virus (SFTSV) infection, we evaluated two different enzyme-linked immunosorbent assay (ELISA) methods using nucleocapsid protein (NP) and...
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Immunogenicity of the nanovaccine containing intimin recombinant protein in the BALB/c mice

Hosseini Z, Amani J, Baghbani Arani F, Nazarian S, Motamedi M, Shafighian F

PURPOSE: Escherichia coli O157:H7 is one of the most important pathogens which create hemorrhagic colitis and hemolytic uremic syndrome in human. It is one of the most prevalent causes of...
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Outbreak investigation of pertussis in an elementary school: a case-control study among vaccinated students

Ryu S, Kim JJ, Chen MY, Jin H, Lee HK, Chun BC

PURPOSE: A pertussis patient from an elementary school, in Gyeonggi Province, Korea, was notified to public health authority on July 25, 2017. Epidemiologic investigation was conducted to identify the magnitude,...
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