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Pathophysiology of copeptin in kidney disease and hypertension

Afsar B

Copeptin is derived from the cleavage of the precursor of arginine vasopressin (AVP), produced in an equimolar ratio in hypothalamus and processed during axonal transport AVP is an unstable peptide...
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Attitudes and preferences for the clinical management of hypertension and hypertension-related cerebrovascular disease in the general practice: results of the Italian hypertension and brain survey

Tocci G, Cicero AF, Salvetti M, Musumeci M, Ferrucci A, Borghi C, Volpe M

BACKGROUND: The aim of this survey was to evaluate attitudes and preferences for the clinical management of hypertension and hypertension-related cerebrovascular diseases (CVD) in Italy. METHODS: A predefined 16-item survey questionnaire...
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Carotid artery intima-media thickness and hypertensive heart disease: a short review

Magnussen

Sustained by its relative ease of assessment, carotid artery intima-media thickness (cIMT) has emerged as an important surrogate marker of target organ damage in hypertensive heart disease over the last...
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Severe carvedilol toxicity without overdose – caution in cirrhosis

Maharaj S, Seegobin K, Perez-Downes J, Bajric B, Chang S, Reddy P

BACKGROUND: Carvedilol is used in the management of hypertension, ischemic heart disease, heart failure and most recently, portal hypertension. It has been associated with improved outcomes regarding variceal bleeding, hepatic...
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Determinants of uncontrolled hypertension among clients on anti-retroviral therapy in Kadoma City, Zimbabwe, 2016

Magande PN, Chirundu D, Gombe NT, Mungati M, Tshimanga

BACKGROUND: Clients on anti-retroviral therapy (ART) are living longer and have risk of hypertension. Side effects of medicines and aging increase this risk. Hypertension prevalence among clients on ART in...
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Hypertensive response to exercise and exercise training in hypertension: odd couple no more

Caldarone , Severi P, Lombardi M, D'Emidio S, Mazza A, Bendini MG, Leggio M

The diagnostic and prognostic implication of exaggerated blood pressure response to exercise has been controversial, with opinions ranging from a benign process to a harbinger of potential cardiovascular morbidity. Nonetheless,...
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Clinical impact of skin autofluorescence on high-sensitivity troponin T in hypertensive patients

Hitsumoto

BACKGROUND: Recent studies have reported the importance of high-sensitivity troponin T (hs-cTnT) or skin autofluorescence (AF) as a cardiovascular risk factor. However, little is known about the relationship between these...
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Identifying treatment response to antihypertensives in patients with obesity-related hypertension

Schrover I, Dorresteijn JAN, Smits JE, Danser AH, Visseren F, Spiering W

BACKGROUND: In patients with obesity-related hypertension (ORH), reaction to antihypertensive medication is likely influenced by patientcharacteristics. METHODS: Effects of aliskiren, moxonidine and hydrochlorothiazide on 24-h blood pressure (BP) were compared to...
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The salt-taste threshold in untreated hypertensive patients

Kim CY, Ye MK, Lee YS

BACKGROUND: The salt-taste threshold can influence the salt appetite, and is thought to be another marker of sodium intake. Many studies have mentioned the relationship between the sodium intake and...
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Association of angiotensinogen gene SNPs and haplotypes with risk of hypertension in eastern Indian population

Purkait P, Halder K, Thakur S, Ghosh Roy , Raychaudhuri P, Bhattacharya S, Sarkar BN, Naidu JM

BACKGROUND: Angiotensinogen (AGT) enzyme comprises a vital module of RAAS system that effectively controls the blood pressure and related cardiovascular functions. Ample association studies have reported the importance of AGT...
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Status of hypertension screening in the Korea National General Health Screening Program: a questionnaire survey on 210 screening centers in two metropolitan areas

Lee SW, Lee HY, Ihm SH, Park SH, Kim TH, Kim HC

BACKGROUND: The purpose of this survey was to evaluate the performance of hypertension screening in medical institutions conducting the national general health screening program of the Republic of Korea. METHODS: We...
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Office orthostatic blood pressure measurements and ambulatory blood pressure monitoring in the prediction of autonomic dysfunction

Alquadan K, Singhania , Koratala A, Ejaz AA

BACKGROUND: In this retrospective analysis we investigated the predictive performance of orthostatic hypotension (OH) and ambulatory blood pressure monitoring (ABP) to predict autonomic dysfunction. METHODS: Statistical associations among the candidate variables...
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Amlodipine Vs. hydrochlorothiazide: is there any disparity in its antihypertensive effect or not?

Jonnalagadda VG, Choudhary , Matety VK

We have read the article “Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic parameters...
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Association between central blood pressure, arterial stiffness, and mild cognitive impairment

Suleman R, Padwal R, Hamilton P, Senthilselvan A, Alagiakrishnan K

BACKGROUND: To determine the relationship between central blood pressure (CBP) indices and mild cognitive impairment (MCI) in adults over the age of 50. METHODS: A cross-sectional study conducted using a non-invasive...
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Blood pressure control and its determinants among diabetes mellitus co-morbid hypertensive patients at Jimma University medical center, South West Ethiopia

Muleta S, Melaku T, Chelkeba L, Assefa D

BACKGROUND: Hypertension is the major contributor to cardiovascular diseases related morbidity and mortality. Blood pressure is not well controlled in the majority of patients with both diabetes and hypertension. The...
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Systolic time ratio measured by impedance cardiography accurately screens left ventricular diastolic dysfunction in patients with arterial hypertension

Nazário Leão R, Marques Silva P, Branco L, Fonseca H, Bento B, Alves M, Virella D, Palma Reis R

BACKGROUND: The use of impedance cardiography (ICG) may play a role in the assessment of cardiac effects of hypertension (HT), especially its hemodynamic features. Hypertensive heart disease involves structural changes...
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Autonomic imbalance captures maternal and fetal circulatory response to pre-eclampsia

Lakhno I

BACKGROUND: Pre-eclampsia (PE) is a gestational disease featured by hypertension, arterial systemic vasculopathy, multiple organ failure and fetal compromise. The aim of the investigation was to determine the role of maternal...
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A multicenter cohort study of primary hypertension in Korea: study design and interim analysis of the Korean registry of target organ damage in hypertension (KorHR)

Choi SW, Han SW, Ok JS, Yoo BS, Shin MS, Park SH, Ryu KH

BACKGROUND: The Korean Registry of Target Organ Damage in Hypertension aims to evaluate the clinical characteristics and prevalence of subclinical target organ damage in Korean hypertensive patients. METHOD: This is a...
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Lifestyle modification practice and associated factors among diagnosed hypertensive patients in selected hospitals, South Ethiopia

Buda ES, Hanfore LK, Fite RO, Buda AS

BACKGROUND: Hypertension is one of the leading causes of disability and death in both developed and developing countries that need urgent strategies to implement interventions that control it. Appropriate lifestyle...
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Differences in left ventricular functional adaptation to arterial stiffness and neurohormonal activation in patients with hypertension: a study with two-dimensional layer-specific speckle tracking echocardiography

Kim D, Shim CY, Hong GR, Park S, Cho I, Chang HJ, Ha JW, Chung N

BACKGROUND: Arterial stiffness increases pressure load to the left ventricle (LV), leading to LV hypertrophy and subendocardial ischemia. Neurohormones stimulate myocardial fibrosis and LV dysfunction. We aimed to explore the...
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