- Platelet-Derived Growth Factor Receptor-α Subunit Targeting Suppresses Metastasis in Advanced Thyroid Cancer In Vitro and In Vivo
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Lin CL, Tsai ML, Chen Yh, Liu WN, Lin CY, Hsu KW, Huang CY, Chang YJ, Wei PL, Chen SH, Huang LC, Lee CH
- KMID: 2519621
- Biomol Ther.
- 2021 Sep;29(5):551-561.
- doi: 10.4062/biomolther.2020.205
Thyroid cancer is the most common endocrine malignancy. Patients with well-differentiated thyroid cancers, such as papillary and follicular cancers, have a favorable prognosis. However, poorly differentiated thyroid cancers, such as... -
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- Cilostazol ameliorates diabetic nephropathy by inhibiting highglucose- induced apoptosis
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Chian CW, Lee YS, Lee YJ, Chen YH, Wang CP, Lee WC, Lee HJ
- KMID: 2505775
- Korean J Physiol Pharmacol.
- 2020 Sep;24(5):403-412.
- doi: 10.4196/kjpp.2020.24.5.403
Diabetic nephropathy (DN) is a hyperglycemia-induced progressivedevelopment of renal insufficiency. Excessive glucose can increase mitochondrialreactive oxygen species (ROS) and induce cell damage, causing mitochondrial dysfunction.Our previous study indicated that cilostazol... -
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- Hepatocyte and mesenchymal stem cell co-transplantation in rats with acute liver failure
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Ho CM, Chen YH, Chien CS, Ho SL, Chen HL, Hu RH, Lee PH
- KMID: 2503886
- Korean J Transplant.
- 2020 Jun;34(2):100-108.
- doi: 10.4285/kjt.2020.34.2.100
Background: Cell therapy is considered a potential alternative to liver transplantation in acute liver failure (ALF). We aimed to evaluate the add-on therapeutic benefit of hepatocyte and mesenchymal stem cell... -
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- Prior uterine myoma and risk of ovarian cancer: a population-based case-control study
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Tseng JJ, Huang CC, Chiang HY, Chen YH, Lin CH
- KMID: 2457151
- J Gynecol Oncol.
- 2019 Sep;30(5):e72.
- doi: 10.3802/jgo.2019.30.e72
OBJECTIVE: Uterine myoma which results in the magnitude of ovarian cancer remains uncertain. This study aimed to assess the association between women with previous uterine myoma and the risk of... -
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- Dexamethasone Downregulates Expressions of 14-3-3β and γ-Isoforms in Mice with Eosinophilic Meningitis Caused by Angiostrongylus cantonensis Infection
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Tsai HC, Chen YH, Yen CM, Chung LY, Wann SR, Lee SS, Chen YS
- KMID: 2453313
- Korean J Parasitol.
- 2019 Jun;57(3):249-256.
- doi: 10.3347/kjp.2019.57.3.249
Steroids are commonly used in patients with eosinophilic meningitis caused by A. cantonensis infections. The mechanism steroids act on eosinophilic meningitis remains unclear. In this mouse experiments, expressions of 14-3-3... -
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- Increased risk of breast cancer in women with uterine myoma: a nationwide, population-based, case-control study
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Tseng JJ, Chen YH, Chiang HY, Lin CH
- KMID: 2413446
- J Gynecol Oncol.
- 2017 May;28(3):e35.
- doi: 10.3802/jgo.2017.28.e35
OBJECTIVE: To evaluate if uterine myoma is associated with breast cancer. METHODS: This case-control study used a nationwide database in Taiwan. We identified 24,315 patients with newly diagnosed breast cancer as... -
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- A Small Case Series of Intravascular Large B-Cell Lymphoma with Unexpected Findings: Subset of Cases with Concomitant Extravascular Central Nervous System (CNS) Involvement Mimicking Primary CNS Lymphoma
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Poropatich K, Dittmann D, Chen YH, Raparia K, Wolniak K, Gao J
- KMID: 2392595
- J Pathol Transl Med.
- 2017 May;51(3):284-291.
- doi: 10.4132/jptm.2017.02.16
BACKGROUND: Intravascular large B-cell lymphoma (IVLBCL) is a rare type of extranodal lymphoma with growth mainly in the lumina of vessels. We studied a small series of IVLBCL and focused... -
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- Does Spore Count Matter in Fungal Allergy?: The Role of Allergenic Fungal Species
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Lin WR, Chen YH, Lee MF, Hsu LY, Tien CJ, Shih FM, Hsiao SC, Wang PH
- KMID: 2295149
- Allergy Asthma Immunol Res.
- 2016 Sep;8(5):404-411.
- doi: 10.4168/aair.2016.8.5.404
PURPOSE: Fungi have been known to be important aeroallergens for hundreds of years. Most studies have focused on total fungal concentration; however, the concentration of specific allergenic fungi may be... -
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- IgE-Binding Epitope Mapping and Tissue Localization of the Major American Cockroach Allergen Per a 2
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Lee MF, Chang CW, Song PP, Hwang GY, Lin SJ, Chen YH
- KMID: 2166685
- Allergy Asthma Immunol Res.
- 2015 Jul;7(4):376-383.
- doi: 10.4168/aair.2015.7.4.376
PURPOSE: Cockroaches are the second leading allergen in Taiwan. Sensitization to Per a 2, the major American cockroach allergen, correlates with clinical severity among patients with airway allergy, but there... -
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- Analysis of Spatial and Temporal Protein Expression in the Cerebral Cortex after Ischemia-Reperfusion Injury
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Chen YH, Chiang YH, Ma HI
- KMID: 2287525
- J Clin Neurol.
- 2014 Apr;10(2):84-93.
- doi: 10.3988/jcn.2014.10.2.84
BACKGROUND AND PURPOSE: Hypoxia, or ischemia, is a common cause of neurological deficits in the elderly. This study elucidated the mechanisms underlying ischemia-induced brain injury that results in neurological sequelae. METHODS:... -
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- N-Acetylcysteine Improves Pancreatic Microcirculation and Alleviates the Severity of Acute Necrotizing Pancreatitis
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Du BQ, Yang YM, Chen YH, Liu XB, Mai G
- KMID: 1431355
- Gut Liver.
- 2013 May;7(3):357-362.
- doi: 10.5009/gnl.2013.7.3.357
BACKGROUND/AIMS: To investigate the beneficial effect of N-Acetylcysteine (NAC) on pancreatic microvascular perfusion in acute necrotizing pancreatitis (ANP). METHODS: Fifty-four rats were divided into a control group, an ANP group and... -
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- Job Stress, Heart Rate Variability and Metabolic Syndrome
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Chang SJ, Koh SB, Choi HR, Woo JM, Cha BS, Park JK, Chen YH, Chung HK
- KMID: 2028289
- Korean J Occup Environ Med.
- 2004 Mar;16(1):70-81.
OBJECTIVE: A growing body of literature has documented that job stress is associated with the development of cardiovascular disease. Nevertheless, the pathophysiological mechanism of this association remains unclear. Therefore, we... -
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