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Platelet-Derived Growth Factor Receptor-α Subunit Targeting Suppresses Metastasis in Advanced Thyroid Cancer In Vitro and In Vivo

Lin CL, Tsai ML, Chen Yh, Liu WN, Lin CY, Hsu KW, Huang CY, Chang YJ, Wei PL, Chen SH, Huang LC, Lee CH

Thyroid cancer is the most common endocrine malignancy. Patients with well-differentiated thyroid cancers, such as papillary and follicular cancers, have a favorable prognosis. However, poorly differentiated thyroid cancers, such as...
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Cilostazol ameliorates diabetic nephropathy by inhibiting highglucose- induced apoptosis

Chian CW, Lee YS, Lee YJ, Chen YH, Wang CP, Lee WC, Lee HJ

Diabetic nephropathy (DN) is a hyperglycemia-induced progressivedevelopment of renal insufficiency. Excessive glucose can increase mitochondrialreactive oxygen species (ROS) and induce cell damage, causing mitochondrial dysfunction.Our previous study indicated that cilostazol...
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Hepatocyte and mesenchymal stem cell co-transplantation in rats with acute liver failure

Ho CM, Chen YH, Chien CS, Ho SL, Chen HL, Hu RH, Lee PH

Background: Cell therapy is considered a potential alternative to liver transplantation in acute liver failure (ALF). We aimed to evaluate the add-on therapeutic benefit of hepatocyte and mesenchymal stem cell...
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Prior uterine myoma and risk of ovarian cancer: a population-based case-control study

Tseng JJ, Huang CC, Chiang HY, Chen YH, Lin CH

OBJECTIVE: Uterine myoma which results in the magnitude of ovarian cancer remains uncertain. This study aimed to assess the association between women with previous uterine myoma and the risk of...
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Dexamethasone Downregulates Expressions of 14-3-3β and γ-Isoforms in Mice with Eosinophilic Meningitis Caused by Angiostrongylus cantonensis Infection

Tsai HC, Chen YH, Yen CM, Chung LY, Wann SR, Lee SS, Chen YS

Steroids are commonly used in patients with eosinophilic meningitis caused by A. cantonensis infections. The mechanism steroids act on eosinophilic meningitis remains unclear. In this mouse experiments, expressions of 14-3-3...
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Increased risk of breast cancer in women with uterine myoma: a nationwide, population-based, case-control study

Tseng JJ, Chen YH, Chiang HY, Lin CH

OBJECTIVE: To evaluate if uterine myoma is associated with breast cancer. METHODS: This case-control study used a nationwide database in Taiwan. We identified 24,315 patients with newly diagnosed breast cancer as...
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A Small Case Series of Intravascular Large B-Cell Lymphoma with Unexpected Findings: Subset of Cases with Concomitant Extravascular Central Nervous System (CNS) Involvement Mimicking Primary CNS Lymphoma

Poropatich K, Dittmann D, Chen YH, Raparia K, Wolniak K, Gao J

BACKGROUND: Intravascular large B-cell lymphoma (IVLBCL) is a rare type of extranodal lymphoma with growth mainly in the lumina of vessels. We studied a small series of IVLBCL and focused...
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Does Spore Count Matter in Fungal Allergy?: The Role of Allergenic Fungal Species

Lin WR, Chen YH, Lee MF, Hsu LY, Tien CJ, Shih FM, Hsiao SC, Wang PH

PURPOSE: Fungi have been known to be important aeroallergens for hundreds of years. Most studies have focused on total fungal concentration; however, the concentration of specific allergenic fungi may be...
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IgE-Binding Epitope Mapping and Tissue Localization of the Major American Cockroach Allergen Per a 2

Lee MF, Chang CW, Song PP, Hwang GY, Lin SJ, Chen YH

PURPOSE: Cockroaches are the second leading allergen in Taiwan. Sensitization to Per a 2, the major American cockroach allergen, correlates with clinical severity among patients with airway allergy, but there...
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Analysis of Spatial and Temporal Protein Expression in the Cerebral Cortex after Ischemia-Reperfusion Injury

Chen YH, Chiang YH, Ma HI

BACKGROUND AND PURPOSE: Hypoxia, or ischemia, is a common cause of neurological deficits in the elderly. This study elucidated the mechanisms underlying ischemia-induced brain injury that results in neurological sequelae. METHODS:...
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N-Acetylcysteine Improves Pancreatic Microcirculation and Alleviates the Severity of Acute Necrotizing Pancreatitis

Du BQ, Yang YM, Chen YH, Liu XB, Mai G

BACKGROUND/AIMS: To investigate the beneficial effect of N-Acetylcysteine (NAC) on pancreatic microvascular perfusion in acute necrotizing pancreatitis (ANP). METHODS: Fifty-four rats were divided into a control group, an ANP group and...
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Job Stress, Heart Rate Variability and Metabolic Syndrome

Chang SJ, Koh SB, Choi HR, Woo JM, Cha BS, Park JK, Chen YH, Chung HK

  • KMID: 2028289
  • Korean J Occup Environ Med.
  • 2004 Mar;16(1):70-81.
OBJECTIVE: A growing body of literature has documented that job stress is associated with the development of cardiovascular disease. Nevertheless, the pathophysiological mechanism of this association remains unclear. Therefore, we...
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