- Nomogram for predicting overall survival in children with neuroblastoma based on SEER database
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Liang SW, Chen G, Luo YG, Chen P, Gu JH, Xu QQ, Dang YW, Qin LT, Lu HP, Huang WT, Huang ZG, Gao L, Chen JB
- KMID: 2504824
- Ann Surg Treat Res.
- 2020 Aug;99(2):118-126.
- doi: 10.4174/astr.2020.99.2.118
Purpose: This study was performed to establish and validate a nomogram for predicting the overall survival in children with neuroblastoma. Methods: The latest clinical data of neuroblastoma in Surveillance, Epidemiology, and... -
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- Comparative Evaluation of Hepatoprotective Activities of Geniposide, Crocins and Crocetin by CCl4-Induced liver Injury in Mice
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Chen P, Chen Y, Wang Y, Cai S, Deng L, Liu J, Zhang H
- KMID: 2170527
- Biomol Ther.
- 2016 Mar;24(2):156-162.
- doi: 10.4062/biomolther.2015.094
Iridoid glycosides (mainly geniposide) and crocetin derivatives (crocins) are the two major active constituents in Gardenia jasminoides Ellis. In the present study, geniposide, crocins, crocin-1 and crocetin were separated from... -
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- Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice
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Hu J, Luo H, Wang J, Tang W, Lu J, Wu S, Xiong Z, Yang G, Chen Z, Lan T, Zhou H, Nie J, Jiang Y, Chen P
- KMID: 2389298
- Exp Mol Med.
- 2017 Aug;49(8):e370.
- doi: 10.1038/emm.2017.122
Chronic high-salt diet-associated renal injury is a key risk factor for the development of hypertension. However, the mechanism by which salt triggers kidney damage is poorly understood. Our study investigated... -
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- Host-Microbiome Interactions in Alcoholic Liver Disease
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Chen P, Schnabl B
- KMID: 1774555
- Gut Liver.
- 2014 May;8(3):237-241.
Alcoholic liver disease is a leading cause of morbidity and liver-related death worldwide. Intestinal bacterial overgrowth and dysbiosis induced by ethanol ingestion play an important role in the pathogenesis of... -
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- Clinical Evidence of Chemotherapy or Endocrine Therapy Maintenance in Patients with Metastatic Breast Cancer: Meta-Analysis of Randomized Clinical Trials and Propensity Score Matching of Multicenter Cohort Study
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Ren W, Yu Y, Hong H, Wang Y, Gao Q, Chen Y, Chen P, Zhao J, Ou Q, Lin D, Fu T, Tan Y, Li C, Xie X, Ye G, Tang J, Yao H
- KMID: 2534183
- Cancer Res Treat.
- 2022 Oct;54(4):1038-1052.
- doi: 10.4143/crt.2021.698
Purpose This study aims to comprehensively evaluate the clinical efficacy of chemotherapy or endocrine therapy maintenance in metastatic breast cancer (MBC) patients. Materials and Methods The meta-analysis of randomized clinical trials... -
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- Hospitalization Due to Asthma Exacerbation: A China Asthma Research Network (CARN) Retrospective Study in 29 Provinces Across Mainland China
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Lin J, Xing B, Tang H, Yang L, Yuan Y, Gu Y, Chen P, Liu X, Zhang J, Liu H, Wang C, Zhou W, Sun D, Chen Y, Chen Z, Huang M, Lin Q, Hu C, Yang X, Huo J, Ye X, Zhou X, Jiang P, Zhang W, Huang Y, Dai L, Liu R, Cai S, Xu J, Zhou J, on behalf of China Asthma Research Network
- KMID: 2471231
- Allergy Asthma Immunol Res.
- 2020 May;12(3):485-495.
- doi: 10.4168/aair.2020.12.3.485
PURPOSE: Details of patients hospitalized for asthma exacerbation in mainland China are lacking. To improve disease control and reduce economic burden, a large sample survey among this patient population is... -
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- Peiminine inhibits myocardial injury and fibrosis after myocardial infarction in rats by regulating mitogen-activated protein kinase pathway
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Chen P, Zhou D, Liu Y, Wang P, Wang W
- KMID: 2526728
- Korean J Physiol Pharmacol.
- 2022 Mar;26(2):87-94.
- doi: 10.4196/kjpp.2022.26.2.87
Myocardial infarction promotes cardiac remodeling and myocardial fibrosis, thus leading to cardiac dysfunction or heart failure. Peiminine has been regarded as a traditional anti-fibrotic Chinese medicine in pulmonary fibrosis. However,... -
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- The Association of SERPINE2 Gene with COPD in a Chinese Han Population
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Wang A, Yin Y, Chen P, Liu Q, Yu Q, Xiao W
- KMID: 1058815
- Yonsei Med J.
- 2011 Nov;52(6):953-960.
- doi: 10.3349/ymj.2011.52.6.953
PURPOSE: Polymorphisms of several candidate genes have been studied and associated with the development of chronic obstructive pulmonary disease (COPD). One such candidate is the SERPINE2 (Serpin peptidase inhibitor, clade... -
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- Prolactin Inhibits BCL6 Expression in Breast Cancer Cells through a MicroRNA-339-5p-Dependent Pathway
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Yan H, Zhao M, Huang S, Chen P, Wu WY, Huang J, Wu ZS, Wu Q
- KMID: 2176318
- J Breast Cancer.
- 2016 Mar;19(1):26-33.
- doi: 10.4048/jbc.2016.19.1.26
PURPOSE: Prolactin (PRL) plays a critical role in breast cancer progression by activating its cognate receptor and promotes the growth and differentiation of breast cancer cells. Studies have shown that... -
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- Internal Mammary Sentinel Lymph Node Biopsy after Neoadjuvant Chemotherapy in Breast Cancer
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Bi Z, Chen P, Liu J, Liu Y, Qiu P, Yang Q, Zheng W, Wang Y
- KMID: 2429823
- J Breast Cancer.
- 2018 Dec;21(4):442-446.
- doi: 10.4048/jbc.2018.21.e49
PURPOSE: The definition of nodal pathologic complete response (pCR) after a neoadjuvant chemotherapy (NAC) just included the evaluation of axillary lymph node (ALN) without internal mammary lymph node. This study... -
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- Risk Factors for Duodenal Stump Leakage after Laparoscopic Gastrectomy for Gastric Cancer
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Gu L, Zhang K, Shen Z, Wang X, Zhu H, Pan J, Zhong X, Khadaroo P, Chen P
- KMID: 2471928
- J Gastric Cancer.
- 2020 Mar;20(1):81-94.
- doi: 10.5230/jgc.2020.20.e4
PURPOSE: Duodenal stump leakage (DSL) is a potentially fatal complication that can occur after gastrectomy, but its underlying risk factors are unclear. This study aimed to investigate the risk factors... -
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- Gut Microbiota Dysbiosis Correlates With Long COVID-19 at One-Year After Discharge
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Zhang D, Zhou Y, Ma Y, Chen P, Tang J, Yang B, Li H, Liang M, Xue Y, Liu Y, Zhang J, Wang X
- KMID: 2541558
- J Korean Med Sci.
- 2023 Apr;38(15):e120.
- doi: 10.3346/jkms.2023.38.e120
Background: Long coronavirus disease 2019 (COVID-19) in recovered patients (RPs) is gradually recognized by more people. However, how long it will last and the underlining mechanism remains unclear. Methods: We conducted... -
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- Inhibition of MicroRNA-15a/16 Expression Alleviates Neuropathic Pain Development through Upregulation of G Protein-Coupled Receptor Kinase 2
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Li T, Wan Y, Sun L, Tao S, Chen P, Liu C, Wang K, Zhou C, Zhao G
- KMID: 2455097
- Biomol Ther.
- 2019 Jul;27(4):414-422.
- doi: 10.4062/biomolther.2018.073
There is accumulating evidence that microRNAs are emerging as pivotal regulators in the development and progression of neuropathic pain. MicroRNA-15a/16 (miR-15a/16) have been reported to play an important role in... -
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- Add-on Tiotropium in Chinese Patients With Moderate Asthma: A Pooled Subgroup Analysis of MezzoTinA-Asthma 1 and 2
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Lin J, Wan H, Kang J, Ma Q, Chen P, Jin M, Wang H, Liu S, Hao Q, Lin Y, Su L, Hu N
- KMID: 2448754
- Allergy Asthma Immunol Res.
- 2019 Jul;11(4):519-528.
- doi: 10.4168/aair.2019.11.4.519
PURPOSE: Asthma affects approximately 30 million patients in China; however, tiotropium data for Chinese patients is limited. This study aimed to assess the efficacy and safety of tiotropium in Chinese... -
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